DIOPT Ortholog Finder Help

Version Details

Version 8 Details
Version 9 Details

Using the text box option:
Gene and/or protein identifiers should be entered one per line. Different types of identifiers can be entered together.

Example (fly genes):

Nmd3
lace
FBgn0000339
FBgn0032679
CG5110
CG5861
par-1
wg

Using the file upload option:
Please upload a text file with one gene/protein per line.

Tutorial

How To Cite:

• Hu Y, Comjean A, Rodiger J, Liu Y, Gao Y, Chung V, Zirin J, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update. Nucleic Acids Research 2021 Jan 8;
  PubmedID: 33104800;
  

• Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics. 2011 Aug 31 ;
  PubmedID: 21880147;
  

DIOPT API

You can access diopt data through an API call. For details see: https://www.flyrnai.org/tools/diopt/web/api

Versions

• Version 9.0 - 2023-
  • Finalized dataset
• 9.0 (beta) Sept 2021 -
  • Revamped UI
  • added 2 species: Mosquito (Anopheles gambiae) and E. coli
  • added 2 sources of annotation (SGD and ECOCYC) and 2 prediction algorithms (sonicParanoid and Domainid)
• 8.5 August 2021 -
  • Revamped UI
• 8.0- August 2019 -
  • Updated Data Sources
• 7.1- March 2018 -
  • User Feedback on missing relationships
• 7.0- Jan 2018 -
  • Updated Data Sources
  • added 3 new algorithms: OrthoFinder, OrthoInspector, Hieranoid as a sources
  • added new species: Arabidopsis (Thale Cress)
• 6.0.3- Oct 2017 - bug fix to error where in some cases where report fails to generate if certain genes are input
• 6.0.2- June 2017 - fix the ID mapping issue of worm genes to include worm gene related eggNOG predictions
• 6.0.1- Jan 2017 - fixed links to pombebase, column header
• 6.0- Dec 2016 -
  • Updated Data Sources
  • added eggNOG as a source
  • Added paralogs
• 5.5- Oct 2016 - Added multi-sequence alignment from target "All" heatmap
• 5.4- Sept 2016 - Added target species "All" and new filter
• 5.3- May 2016 - Added more prediction tools (Panther, HGNC and ZFIN)
• 5.2.1- April 2016 - Added orthologous rank
  
  • High: best score both ways AND DIOPT score >=2
  • Moderate:
    1. (best score forward or reverse) AND DIOPT score >=2
    2. DIOPT score >=4
  • Low: all others
• 5.2- April 2016 - Added New Species (Rattus norvegicus)
• 5.1.1 - December 2015 - Added Best forward and reverse columns
• 5.1 - November 2015 - Upgraded gene matching algorithm
• 5.0 - November 2015 - Upgraded data sources to version 5