Transcription Factor 2 Target Gene

» Search for Transcription Factors
Transcription Factor-to-Target Gene (TF2TG) makes it possible to use high-throughput and other transcription factor binding site-related and transcriptomics data sets to predict what TFs might regulate a given gene of interest. The resource is designed to help answer the following questions: What TFs might bind to the promoter region of a given gene? What TF peaks are observed in the promoter region of a given gene and in a certain context, based on ChIP-seq or ChIP-chip data? What are potential long-distance enhancers that might regulate expression of the gene? As such, TF2TG should help you design specific experiments to test transcription factor network control of a given gene of interest.

ChIP & ATAC seq Metadata

**NEW** features:

Preprint of the manuscript is available
New search windows are added (1k and 2k) besides (5k and 10k)
Updated the peak callings of modERN ChIP-seq datasets from 2024 publication
FlyBase release 6.60 (Oct 2024)
RedFly & FlyBase regulatory regions (Oct 2024)
Embedded JBrowse view with summary table
Filter table results + sort by multiple columns
MOODS motif scan results + input PWMs
Annotated TSS distance + relative location
Raw ChIP peaks + annotated peak location tracks

TF Search

Enter a gene to find all potential TFs that might bind to the promoter/intron region

Gene Search

Enter a TF to find all potential target genes

1. Enter TF FBgn or Symbol
Note: Search is case sensitive.

2. Select Motif Source

3. Peak Location Datasets

4. Distance Result (Include Hi-C, RedFly & FlyBase)

5. Select Distance Cutoff

Region Search

Enter coordinates to find the potential TF binding sites

1. Enter Location

Chromosome:

Start:

Stop:

Sequence Search

Enter genomic sequence to find the potential TF binding sites

1. Enter Sequence

Sequence:

Hi-C Search

Enter coordinates to find interacting regions

1. Enter Location

Chromosome:

Start:

Stop: