Marker Genes

Dataset: FCAv2_malpighian_tubule_10x

  • tissue: Malpighian tubule
  • ontology: Malpighian tubule
  • genotype: W1118; Yw; UAS-UNC84GFP
  • stage: Adult
  • treatment condition: WT
  • cell/nucleus: Nuclei
  • pmid: 9000000003_11
  • subset name: mixed
  • total genes: 12843
  • clustering: Scanpy
  • pseudotime: None
  • link: https://flycellatlas.org/

Rows:2561
dataset id cluster id cluster name cell type name sample id gene symbol entrez geneid species specific geneid
avg log fc (?)
pct 1 pct 2 p value padj
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule hth 41273 FBgn0001235 7.03061437606812 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Scp2 42015 FBgn0020907 6.92053556442261 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule bi 31379 FBgn0000179 6.69415092468262 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Nlg2 33962 FBgn0031866 5.7316107749939 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule NijA 39215 FBgn0036101 5.59510564804077 1.2047283200761e-35
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Debcl 53585 FBgn0029131 5.52141094207764 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule asRNA:CR44018 14462448 FBgn0264788 4.83657836914062 3.70336085144168e-227
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Dh31-R 36475 FBgn0052843 4.80222272872925 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR44150 14462733 FBgn0264999 4.79918050765991 1.40074894574086e-56
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG18095 34823 FBgn0028872 4.74830484390259 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR46208 26067519 FBgn0267927 4.66969442367554 3.74557936001356e-68
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Cyp313a3 41488 FBgn0038007 4.60626125335693 0.000350589906251
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Camta 35974 FBgn0259234 4.5081148147583 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Sr-CIII 44382 FBgn0020376 4.46341800689697 0.01910203742175
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG8547 36586 FBgn0033919 4.38556098937988 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Best2 38727 FBgn0035696 4.36247062683105 3.67552269111238e-177
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Doc1 39039 FBgn0028789 4.33545112609863 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule htl 42160 FBgn0010389 4.32649803161621 1.58973949427667e-122
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule dac 34982 FBgn0005677 4.29355764389038 2.55028313155807e-304
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Pkcdelta 32191 FBgn0259680 4.28738212585449 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule PMCA 43787 FBgn0259214 4.2544322013855 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Amnionless 33199 FBgn0025686 4.19495820999146 4.00597311149232e-37
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule numb 34263 FBgn0002973 4.1888542175293 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG8620 50310 FBgn0040837 4.18649244308472 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Rh50 38589 FBgn0028699 4.16322994232178 7.64476271960319e-24
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule wtrw 40931 FBgn0260005 4.13776206970215 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR44423 19835580 FBgn0265596 4.12322521209717 3.29078652137251e-25
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Ptp10D 32115 FBgn0004370 4.1087212562561 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Ddc 35190 FBgn0000422 4.04818058013916 7.42678200461783e-64
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG7634 40394 FBgn0037101 4.03798532485962 8.82420421282548e-12
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Syt1 33473 FBgn0004242 4.01442623138428 3.55722410268072e-07
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Ace 41625 FBgn0000024 3.96616244316101 5.88833760176444e-238
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR44241 19835609 FBgn0265176 3.94035077095032 8.5016330621748e-06
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Doc2 39038 FBgn0035956 3.91128659248352 1.21380716115266e-189
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG5758 35083 FBgn0032666 3.82896876335144 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CAH1 34786 FBgn0027844 3.82012796401978 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Muc11A 32174 FBgn0052656 3.81846380233765 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Trpm 36694 FBgn0265194 3.74591660499573 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG14246 3772140 FBgn0040608 3.74017286300659 4.58396810814774e-31
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule SLO2 5740325 FBgn0261698 3.71634411811829 2.51974411199576e-06
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Dgk 35738 FBgn0085390 3.70343995094299 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG16762 38310 FBgn0035343 3.68534564971924 4.58727534389782e-242
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule wupA 32794 FBgn0283471 3.65770769119263 2.35248763523792e-268
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG16743 34517 FBgn0032322 3.65731525421143 2.96268770570074e-278
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG14963 38383 FBgn0035409 3.65248966217041 8.09043083322843e-239
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG43102 42137 FBgn0262562 3.58978343009949 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG8837 33545 FBgn0031520 3.56869983673096 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Irk1 42742 FBgn0265042 3.55197668075562 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule betaggt-I 33704 FBgn0015000 3.50654339790344 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule svp 41491 FBgn0003651 3.47868871688843 1.86361361509934e-159
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule ND-51L2 36695 FBgn0034007 3.45520782470703 5.37907236667403e-62
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Prm 39002 FBgn0003149 3.43118739128113 7.33342733653919e-16
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule asRNA:CR45146 19835064 FBgn0266639 3.39951920509338 3.41441753646208e-05
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Skeletor 3772559 FBgn0262717 3.38550925254822 0.020823375409859
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule TpnC73F 39916 FBgn0010424 3.38522839546204 2.44253751903309e-06
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG9717 43636 FBgn0039789 3.38486766815186 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Tim17a2 40632 FBgn0037307 3.37757873535156 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule pum 41094 FBgn0003165 3.37179589271545 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Rpt6R 43635 FBgn0039788 3.30479645729065 8.60280408885246e-31
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG3655 31056 FBgn0040397 3.26379299163818 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule rdgC 40224 FBgn0265959 3.26295495033264 3.283969814482e-71
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lov 38007 FBgn0266129 3.25846314430237 1.22103545418727e-21
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule bnl 42356 FBgn0014135 3.25127696990967 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule vn 38657 FBgn0003984 3.24824023246765 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Ten-a 32183 FBgn0267001 3.22950625419617 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR43717 14462653 FBgn0263870 3.19771337509155 1.03251846828272e-30
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule jp 34274 FBgn0032129 3.17634081840515 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Zip48C 36273 FBgn0033665 3.14842367172241 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Irk3 35131 FBgn0032706 3.14646100997925 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG15096 37170 FBgn0034394 3.14622139930725 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG4928 32682 FBgn0027556 3.12980103492737 5.68960714536574e-211
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG8673 34105 FBgn0031986 3.1222779750824 0.00071920805709
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lama 38610 FBgn0016031 3.10829067230225 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Fur1 47220 FBgn0004509 3.02027583122253 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG13455 39667 FBgn0036498 2.96988677978516 6.89906513375542e-41
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Tsp42Ee 35614 FBgn0029506 2.96061706542969 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG9171 33807 FBgn0031738 2.95929670333862 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule danr 43020 FBgn0039283 2.95852065086365 1.55540405731665e-103
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule dan 43023 FBgn0039286 2.95112133026123 1.07763647710823e-12
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG6125 41882 FBgn0038337 2.9475302696228 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CanA-14F 8674098 FBgn0267912 2.92214226722717 3.76781635364039e-304
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Indy 40049 FBgn0036816 2.91886401176453 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Best1 53431 FBgn0040238 2.91453194618225 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG31248 40853 FBgn0051248 2.90632700920105 5.98273671643709e-55
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG42846 10178831 FBgn0262035 2.88961172103882 7.33833768103272e-134
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule asRNA:CR31912 14462706 FBgn0051912 2.854412317276 4.99280647369019e-44
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule ex 33218 FBgn0004583 2.83099007606506 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG3168 31612 FBgn0029896 2.79298734664917 3.7757423678639e-248
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule olf186-F 37040 FBgn0041585 2.78889393806458 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule NfI 43782 FBgn0042696 2.78293895721436 0.004395239965165
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Pgant8 39715 FBgn0036529 2.76760745048523 3.48834663369122e-09
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule gom 43934 FBgn0029084 2.75161147117615 2.63357325761575e-14
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule GstD10 59240 FBgn0042206 2.74382567405701 2.06586914422347e-35
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Dic61B 38020 FBgn0263988 2.72781705856323 2.67151347959328e-107
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule GILT2 42788 FBgn0039099 2.72046804428101 9.90631941243194e-73
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Bsg 318841 FBgn0261822 2.71243596076965 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CapaR 40393 FBgn0037100 2.70292139053345 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG31019 318558 FBgn0051019 2.68675708770752 1.20593807436419e-59
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG34155 4379867 FBgn0083991 2.67650032043457 0.016580850741421
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG15431 33646 FBgn0031602 2.67636823654175 4.15375046958563e-16
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG14245 3772449 FBgn0039452 2.66859364509583 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule a 43852 FBgn0000008 2.63998460769653 4.90613903134471e-145
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule mtd 45467 FBgn0013576 2.62578701972961 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule kuz 34772 FBgn0259984 2.61942958831787 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Spn31A 34339 FBgn0032178 2.6179027557373 9.2590956380251e-10
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG31538 318790 FBgn0051538 2.60337209701538 5.453203560847e-180
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG43078 38981 FBgn0262508 2.59427928924561 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG3857 2768908 FBgn0023520 2.57797265052795 2.31326993733094e-95
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Swim 37537 FBgn0034709 2.5763099193573 6.95371513830531e-223
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Sr-CI 33621 FBgn0014033 2.57156205177307 0.045728800785107
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG30323 246539 FBgn0050323 2.54320955276489 2.67260672179742e-24
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule ct 44540 FBgn0004198 2.53823256492615 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG43897 39153 FBgn0264489 2.52270770072937 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule IP3K1 34300 FBgn0032147 2.5205192565918 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule meng 33948 FBgn0031855 2.52030515670776 1.50534648928246e-42
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG7912 43561 FBgn0039736 2.50628614425659 3.8676820309025e-08
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG34417 31591 FBgn0085446 2.46798610687256 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule SmydA-3 34502 FBgn0262599 2.45771765708923 0.000139546070624
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lobo 4379864 FBgn0083946 2.45089364051819 0.04569487194304
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CrebA 39682 FBgn0004396 2.43850803375244 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule asRNA:CR45131 19835632 FBgn0266624 2.41665983200073 2.73143470388824e-35
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG1468 31920 FBgn0030157 2.4094398021698 1.79798946135695e-19
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Muc96D 318737 FBgn0051439 2.38960886001587 8.59766253479738e-54
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Gdap2 59173 FBgn0042135 2.38653445243835 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Hmgcr 42803 FBgn0263782 2.37435603141785 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule alrm 43074 FBgn0039332 2.37111759185791 1.69661696957117e-38
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG18746 59142 FBgn0042103 2.36170077323914 1.75300536365686e-17
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Eaat1 34251 FBgn0026439 2.34464192390442 1.20120826310524e-132
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR44973 19835948 FBgn0266308 2.3379921913147 5.38934461162105e-09
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG42329 33312 FBgn0259229 2.33097314834595 0.006629245936879
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule btsz 3346167 FBgn0266756 2.3211088180542 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG31176 42554 FBgn0051176 2.30796790122986 2.92340255877466e-17
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule LpR1 2768687 FBgn0066101 2.30602860450745 2.88534623356064e-128
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule sdt 44861 FBgn0261873 2.29657125473022 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Ziz 34030 FBgn0260486 2.27400875091553 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule olf413 40453 FBgn0037153 2.27266430854797 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG9813 41644 FBgn0038143 2.27115702629089 0.00127310979223
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG31663 33363 FBgn0051663 2.27005863189697 1.76271639475759e-246
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule asRNA:CR43259 12798268 FBgn0262904 2.24392604827881 6.54024224676237e-14
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Idgf5 37104 FBgn0064237 2.2337052822113 0.000719808037698
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG5151 39772 FBgn0036576 2.23249197006226 2.53677486602165e-193
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR42839 10178956 FBgn0262028 2.22044825553894 0
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule out 32926 FBgn0259834 2.21078276634216 9.17804394256448e-148
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG34172 5740746 FBgn0085201 2.20881223678589 0.040193919507108
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG17716 36521 FBgn0000633 2.19965887069702 1.44233017578168e-201
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule C3G 31618 FBgn0259228 2.17507314682007 2.38787926332917e-287
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule mgl 8674055 FBgn0261260 2.16236257553101 3.07825540984117e-233
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Cbs 33081 FBgn0031148 2.15452718734741 3.00213274035292e-08
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule Dab 39866 FBgn0000414 2.14039301872253 1.33896212562747e-305
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG44245 19835749 FBgn0265180 2.13466191291809 2.72564560668028e-271
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG31637 33914 FBgn0051637 2.12891221046448 6.73903762232368e-307
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR46024 26067345 FBgn0267688 2.12853074073792 8.86017143445999e-19
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG43072 12798436 FBgn0262482 2.11958837509155 0.000464419242551
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG8870 41645 FBgn0038144 2.1142361164093 0.026637224754641
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG14490 37041 FBgn0034281 2.09369874000549 1.96505392233886e-06
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG14688 41275 FBgn0037819 2.08711647987366 5.8168069538316e-98
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG3625 33198 FBgn0031245 2.08248019218445 3.07389394796075e-143
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule CG7378 32888 FBgn0030976 2.08044481277466 2.15648313032719e-105
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule lncRNA:CR43461 12797940 FBgn0263415 2.07943391799927 3.62312393005436e-149
133 3 adult Malpighian tubule principal cell of initial segment malphighian_tubule chinmo