Marker Genes

Dataset: Single-cell transcriptomic analysis of Alzheimer's disease

  • tissue: Prefrontal cortex
  • ontology: Brain
  • genotype: -
  • stage: Adult
  • treatment condition: WT, Alzheimers
  • cell/nucleus: Nuclei
  • pmid: 31042697
  • subset name: all
  • total genes: 17926
  • clustering: Fishers exact test
  • pseudotime: None
  • link:

Rows:177
dataset id cluster id cluster name cell type name sample id gene symbol entrez geneid species specific geneid
avg log fc (?)
pct 1 pct 2 p value padj
104 16 Ex8 Excitatory neurons all CHN1 1123 1943 1.47 0
104 16 Ex8 Excitatory neurons all MAP1B 4131 6836 2.05 0
104 16 Ex8 Excitatory neurons all TUBA1B 10376 18809 2.23 0
104 16 Ex8 Excitatory neurons all CALM1 801 1442 2.05 0
104 16 Ex8 Excitatory neurons all SNAP25 6616 11132 1.64 0
104 16 Ex8 Excitatory neurons all HSP90AA1 3320 5253 2.56 3.61e-299
104 16 Ex8 Excitatory neurons all GAPDH 2597 4141 2.14 1.14e-225
104 16 Ex8 Excitatory neurons all FTH1 2495 3976 2.09 3.2e-162
104 16 Ex8 Excitatory neurons all ATP1B1 481 804 2.08 9.16e-155
104 16 Ex8 Excitatory neurons all RTN4 57142 14085 1.75 1.07e-154
104 16 Ex8 Excitatory neurons all SPARCL1 8404 11220 1.84 4.07e-150
104 16 Ex8 Excitatory neurons all PEBP1 5037 8630 2.07 1.58e-148
104 16 Ex8 Excitatory neurons all CKB 1152 1991 2.16 1.97e-141
104 16 Ex8 Excitatory neurons all TMSB4X 7114 11881 2.22 1.61e-131
104 16 Ex8 Excitatory neurons all HSP90AB1 3326 5258 1.7 1.09e-118
104 16 Ex8 Excitatory neurons all RTN1 6252 10467 1.48 4e-106
104 16 Ex8 Excitatory neurons all CALM3 808 1449 1.94 7.19e-103
104 16 Ex8 Excitatory neurons all STMN2 11075 10577 2.35 6.12e-101
104 16 Ex8 Excitatory neurons all UCHL1 7345 12513 1.84 4.71e-97
104 16 Ex8 Excitatory neurons all BEX3 27018 13388 2.23 3.49e-91
104 16 Ex8 Excitatory neurons all VSNL1 7447 12722 1.64 2.75e-88
104 16 Ex8 Excitatory neurons all SYT1 6857 11509 0.58 1.97e-83
104 16 Ex8 Excitatory neurons all GNAO1 2775 4389 0.55 4.67e-79
104 16 Ex8 Excitatory neurons all CLU 1191 2095 2.12 3.77e-76
104 16 Ex8 Excitatory neurons all DYNLL1 8655 15476 2.07 1.63e-74
104 16 Ex8 Excitatory neurons all SORL1 6653 11185 0.61 4.6e-70
104 16 Ex8 Excitatory neurons all PRKACB 5567 9381 0.6 4.64e-64
104 16 Ex8 Excitatory neurons all TRIM2 23321 15974 0.74 6.84e-64
104 16 Ex8 Excitatory neurons all THY1 7070 11801 1.96 3.12e-59
104 16 Ex8 Excitatory neurons all MAPT 4137 6893 0.5 1.01e-58
104 16 Ex8 Excitatory neurons all GAS7 8522 4169 0.75 5.34e-58
104 16 Ex8 Excitatory neurons all PCSK1N 27344 17301 2.13 1.2e-55
104 16 Ex8 Excitatory neurons all TUBB2A 7280 12412 2.61 5.54e-54
104 16 Ex8 Excitatory neurons all STMN1 3925 6510 1.87 6.38e-54
104 16 Ex8 Excitatory neurons all BEX1 55859 1036 2.17 2.8e-53
104 16 Ex8 Excitatory neurons all PIK3R1 5295 8979 0.62 2.59e-52
104 16 Ex8 Excitatory neurons all RTN3 10313 10469 1.33 4.53e-52
104 16 Ex8 Excitatory neurons all ENC1 8507 3345 1.67 6.71e-51
104 16 Ex8 Excitatory neurons all NEFL 4747 7739 2.5 2.26e-50
104 16 Ex8 Excitatory neurons all CAP2 10486 20039 0.89 1.04e-49
104 16 Ex8 Excitatory neurons all ATP2B2 491 815 0.63 1.64e-48
104 16 Ex8 Excitatory neurons all CCK 885 1569 1.97 2.71e-47
104 16 Ex8 Excitatory neurons all ALDOA 226 414 2.1 1.6e-45
104 16 Ex8 Excitatory neurons all NRGN 4900 8000 1.48 2.35e-45
104 16 Ex8 Excitatory neurons all YWHAH 7533 12853 1.96 1.1e-44
104 16 Ex8 Excitatory neurons all MARCHF6 10299 30550 1.03 2.6e-44
104 16 Ex8 Excitatory neurons all NUAK1 9891 14311 0.96 6.81e-44
104 16 Ex8 Excitatory neurons all NAP1L1 4673 7637 0.93 1.13e-43
104 16 Ex8 Excitatory neurons all YWHAG 7532 12852 1.88 2.01e-43
104 16 Ex8 Excitatory neurons all TMSB10 9168 11879 2.01 1.04e-42
104 16 Ex8 Excitatory neurons all SCAMP5 192683 30386 0.93 8.09e-40
104 16 Ex8 Excitatory neurons all PSAP 5660 9498 1.87 6.73e-39
104 16 Ex8 Excitatory neurons all GNB1 2782 4396 1.05 2.74e-38
104 16 Ex8 Excitatory neurons all MAPK1 5594 6871 1.01 5.81e-37
104 16 Ex8 Excitatory neurons all SIRPA 140885 9662 1.05 2.4e-36
104 16 Ex8 Excitatory neurons all SYN1 6853 11494 0.94 3.28e-36
104 16 Ex8 Excitatory neurons all ATL1 51062 11231 1.1 3.71e-36
104 16 Ex8 Excitatory neurons all CAMK2N1 55450 24190 0.89 7.15e-36
104 16 Ex8 Excitatory neurons all NEFM 4741 7734 2.94 1.5e-35
104 16 Ex8 Excitatory neurons all SNCG 6623 11141 3.32 2.8e-35
104 16 Ex8 Excitatory neurons all KIF21A 55605 19349 1.1 4.26e-35
104 16 Ex8 Excitatory neurons all HSPH1 10808 16969 1.1 1.5e-34
104 16 Ex8 Excitatory neurons all CYFIP2 26999 13760 1.15 9.85e-32
104 16 Ex8 Excitatory neurons all NUCKS1 64710 29923 0.99 8.43e-31
104 16 Ex8 Excitatory neurons all CAMK2G 818 1463 1.26 1.61e-30
104 16 Ex8 Excitatory neurons all TSPAN7 7102 11854 1.99 1.72e-30
104 16 Ex8 Excitatory neurons all BSG 682 1116 0.98 2.7e-30
104 16 Ex8 Excitatory neurons all ACTB 60 132 1.6 3.11e-30
104 16 Ex8 Excitatory neurons all YWHAZ 7534 12855 1.12 3.95e-30
104 16 Ex8 Excitatory neurons all ENO2 2026 3353 1.79 5.72e-30
104 16 Ex8 Excitatory neurons all PLD3 23646 17158 0.97 1.39e-29
104 16 Ex8 Excitatory neurons all PPP2R1A 5518 9302 1.05 3.49e-29
104 16 Ex8 Excitatory neurons all TMEM130 222865 25429 1.17 3.5e-29
104 16 Ex8 Excitatory neurons all PKM 5315 9021 1.78 2.08e-28
104 16 Ex8 Excitatory neurons all SEC62 7095 11846 1.3 1.16e-27
104 16 Ex8 Excitatory neurons all NUDT3 11165 8050 1.31 7.73e-27
104 16 Ex8 Excitatory neurons all OCIAD1 54940 16074 1.3 2.55e-25
104 16 Ex8 Excitatory neurons all EIF4A2 1974 3284 1.65 3.05e-25
104 16 Ex8 Excitatory neurons all PTMA 5757 9623 1.22 7.33e-25
104 16 Ex8 Excitatory neurons all ELAVL4 1996 3315 1.03 1.48e-23
104 16 Ex8 Excitatory neurons all YWHAB 7529 12849 1.75 1.12e-22
104 16 Ex8 Excitatory neurons all KCNAB2 8514 6229 1.35 1.47e-22
104 16 Ex8 Excitatory neurons all FAIM2 23017 17067 1.64 1.61e-22
104 16 Ex8 Excitatory neurons all KIF1A 547 888 1.26 4.15e-22
104 16 Ex8 Excitatory neurons all SYP 6855 11506 0.99 4.6e-22
104 16 Ex8 Excitatory neurons all TOLLIP 54472 16476 1.39 7.86e-22
104 16 Ex8 Excitatory neurons all DDX24 57062 13266 1.16 1.63e-21
104 16 Ex8 Excitatory neurons all SERINC3 10955 11699 1.37 6.55e-21
104 16 Ex8 Excitatory neurons all NDRG4 65009 14466 1.83 1.5e-19
104 16 Ex8 Excitatory neurons all MORF4L1 10933 16989 1.27 1.53e-19
104 16 Ex8 Excitatory neurons all SELENOW 6415 10752 1.97 2.41e-19
104 16 Ex8 Excitatory neurons all PGM2L1 283209 20898 1.43 5.17e-19
104 16 Ex8 Excitatory neurons all TOMM20 9804 20947 1.41 8.55e-19
104 16 Ex8 Excitatory neurons all CLTC 1213 2092 1.51 1.41e-18
104 16 Ex8 Excitatory neurons all PRNP 5621 9449 1.22 8.51e-18
104 16 Ex8 Excitatory neurons all SLC12A5 57468 13818 1.46 8.52e-18
104 16 Ex8 Excitatory neurons all PPIA 5478 9253 1.79 1.79e-17
104 16 Ex8 Excitatory neurons all PNMA2 10687 9159 1.42 2.37e-17
104 16 Ex8 Excitatory neurons all CAMK2A 815 1460 0.85 3.08e-17
104 16 Ex8 Excitatory neurons all EEF1A1 1915 3189 1.57 6.02e-17
104 16 Ex8 Excitatory neurons all SARAF 51669 28789 1.87 8.87e-17
104 16 Ex8 Excitatory neurons all NSG2 51617 24955 1.49 1.06e-16
104 16 Ex8 Excitatory neurons all TLE5 166 307 1.39 1.23e-16
104 16 Ex8 Excitatory neurons all PHYHIP 9796 16865 0.86 8.94e-16
104 16 Ex8 Excitatory neurons all APLP2 334 598 1.58 9.52e-16
104 16 Ex8 Excitatory neurons all CAMK2B 816 1461 0.73 1.13e-14
104 16 Ex8 Excitatory neurons all SEPTIN7 989 1717 1.16 4.4e-14
104 16 Ex8 Excitatory neurons all DYNLRB1 83658 15468 1.44 5.62e-14
104 16 Ex8 Excitatory neurons all DYNC1H1 1778 2961 1.35 1.08e-13
104 16 Ex8 Excitatory neurons all RAB3A 5864 9777 2.12 1.88e-13
104 16 Ex8 Excitatory neurons all PRKAR1B 5575 9390 1.2 2.51e-13
104 16 Ex8 Excitatory neurons all SCG5 6447 10816 2.12 1.08e-12
104 16 Ex8 Excitatory neurons all SV2A 9900 20566 1.33 1.1e-12
104 16 Ex8 Excitatory neurons all TSPYL1 7259 12382 1 1.28e-12
104 16 Ex8 Excitatory neurons all PSD3 23362 19093 0.79 1.7e-12
104 16 Ex8 Excitatory neurons all CLSTN1 22883 17447 1.53 1.72e-12
104 16 Ex8 Excitatory neurons all NDUFA4 4697 7687 2.19 2.67e-12
104 16 Ex8 Excitatory neurons all CCNI 10983 1595 1.31 3.09e-12
104 16 Ex8 Excitatory neurons all PJA2 9867 17481 1.34 5.35e-12
104 16 Ex8 Excitatory neurons all ATP2A2 488 812 1.52 1.1e-11
104 16 Ex8 Excitatory neurons all RAC1 5879 9801 1.54 1.47e-11
104 16 Ex8 Excitatory neurons all WBP2 23558 12738 1.6 2.81e-11
104 16 Ex8 Excitatory neurons all SNCB 6620 11140 1.69 7.31e-11
104 16 Ex8 Excitatory neurons all RHBDD2 57414 23082 1.33 7.95e-11
104 16 Ex8 Excitatory neurons all DNM1 1759 2972 0.77 8.14e-11
104 16 Ex8 Excitatory neurons all SEZ6L2 26470 30844 1.62 1.16e-10
104 16 Ex8 Excitatory neurons all DIRAS2 54769 19323 1.65 3.07e-10
104 16 Ex8 Excitatory neurons all SLC17A7 57030 16704 1 3.41e-10
104 16 Ex8 Excitatory neurons all SNCA 6622 11138 1.11 2.25e-09
104 16 Ex8 Excitatory neurons all EIF1AX 1964 3250 1.68 8.57e-09
104 16 Ex8 Excitatory neurons all PGRMC1 10857 16090 1.7 1.68e-08
104 16 Ex8 Excitatory neurons all MDH1 4190 6970 2.18 2.74e-08
104 16 Ex8 Excitatory neurons all ATP6V0B 533 861 1.71 4.25e-08
104 16 Ex8 Excitatory neurons all NSF 4905 8016 1.09 4.83e-08
104 16 Ex8 Excitatory neurons all STMN3 50861 15926 1.5 8.78e-08
104 16 Ex8 Excitatory neurons all SULT4A1 25830 14903 1.63 1.5e-07
104 16 Ex8 Excitatory neurons all GDI1 2664 4226 1.23 2.84e-07
104 16 Ex8 Excitatory neurons all BASP1 10409 957 0.77 2.99e-07
104 16 Ex8 Excitatory neurons all TUBA4A 7277 12407 2.34 5.56e-07
104 16 Ex8 Excitatory neurons all RPL13 6137 10303 1.69 6.01e-07
104 16 Ex8 Excitatory neurons all CFL1 1072 1874 1.89 9.88e-07
104 16 Ex8 Excitatory neurons all GNAS 2778 4392 1.35 1.01e-06
104 16 Ex8 Excitatory neurons all ACTG1 71 144 1.87 1.44e-06
104 16 Ex8 Excitatory neurons all SYT11 23208 19239 1.5 1.99e-06
104 16 Ex8 Excitatory neurons all RTL8C 8933 2569 1.83 2.13e-06
104 16 Ex8 Excitatory neurons all GABRA1 2554 4075 1.35 4.3e-06
104 16 Ex8 Excitatory neurons all SPOCK2 9806 13564 1.79 4.62e-06
104 16 Ex8 Excitatory neurons all LY6H 4062 6728 1.43 7.81e-06
104 16 Ex8 Excitatory neurons all ATP6V1E1 529 857 1.75 1.33e-05
104 16 Ex8 Excitatory neurons all ARL6IP5 10550 16937 1.82 1.74e-05
104 16 Ex8 Excitatory neurons all NDFIP1 80762 17592 1.36 3.22e-05
104 16 Ex8 Excitatory neurons all HINT1 3094 4912 2.13 4.51e-05
104 16 Ex8 Excitatory neurons all RPL15 6138 10306 1.9 7.32e-05
104 16 Ex8 Excitatory neurons all NECAB1 64168 20983 0.69 8.34e-05
104 16 Ex8 Excitatory neurons all ARPP19 10776 16967 1.24 9.79e-05
104 16 Ex8 Excitatory neurons all UQCRH 7388 12590 2.08 0.000122599074278
104 16 Ex8 Excitatory neurons all GHITM 27069 17281 2.02 0.000225148335506
104 16 Ex8 Excitatory neurons all SERPINI1 5274 8943 1.3 0.000317723871565
104 16 Ex8 Excitatory neurons all APP 351 620 1.22 0.000352319808003
104 16 Ex8 Excitatory neurons all EID1 23741 1191 1.63 0.000385796974314
104 16 Ex8 Excitatory neurons all RAB6B 51560 14902 1.53 0.000406622517713
104 16 Ex8 Excitatory neurons all ATP5F1B 506 830 1.85 0.000513807728369
104 16 Ex8 Excitatory neurons all SOD1 6647 11179 2.13 0.000581702925414
104 16 Ex8 Excitatory neurons all NAPB 63908 15751 1.61 0.000600239105391
104 16 Ex8 Excitatory neurons all SERINC1 57515 13464 1.76 0.00104775848771
104 16 Ex8 Excitatory neurons all EIF1 10209 3249 1.41 0.001146544976774
104 16 Ex8 Excitatory neurons all BEX4 56271 25475 1.91 0.001172282559733
104 16 Ex8 Excitatory neurons all ARF1 375 652 1.7 0.001655611039163
104 16 Ex8 Excitatory neurons all FTL 2512 3999 1.7 0.00174535873852
104 16 Ex8 Excitatory neurons all SLC25A3 5250 10989 2.03 0.00197123196902
104 16 Ex8 Excitatory neurons all SLC22A17 51310 23095 1.53 0.002044144501428
104 16 Ex8 Excitatory neurons all ATP5IF1 93974 871 2.01 0.002116709320278
104 16 Ex8 Excitatory neurons all PGAM1 5223 8888 2.16 0.003477993685222
104 16 Ex8 Excitatory neurons all GPX4 2879 4556 1.84 0.005182304555254
104 16 Ex8 Excitatory neurons all TUBA1A 7846 20766 1.99 0.005773528842032
104 16 Ex8 Excitatory neurons all TMEM59L 25789 13237 1.44 0.008746160436466
104 16 Ex8 Excitatory neurons all ITM2B 9445 6174 1.79 0.009768766168569