Marker Genes

Dataset: Single-cell transcriptomic analysis of Alzheimer's disease

  • tissue: Prefrontal cortex
  • ontology: Brain
  • genotype: -
  • stage: Adult
  • treatment condition: WT, Alzheimers
  • cell/nucleus: Nuclei
  • pmid: 31042697
  • subset name: all
  • total genes: 17926
  • clustering: Fishers exact test
  • pseudotime: None
  • link:

Rows:231
dataset id cluster id cluster name cell type name sample id gene symbol entrez geneid species specific geneid
avg log fc (?)
pct 1 pct 2 p value padj
104 12 Ex4 Excitatory neurons all CAMK2N1 55450 24190 0.82 0
104 12 Ex4 Excitatory neurons all RASGEF1B 153020 24881 0.81 0
104 12 Ex4 Excitatory neurons all SLC26A3 1811 3018 0.86 0
104 12 Ex4 Excitatory neurons all PHYHIP 9796 16865 0.92 0
104 12 Ex4 Excitatory neurons all GRIN1 2902 4584 0.64 0
104 12 Ex4 Excitatory neurons all LINGO1 84894 21205 0.66 6.99e-297
104 12 Ex4 Excitatory neurons all PTK2B 2185 9612 0.89 5.45e-287
104 12 Ex4 Excitatory neurons all DHFR 1719 2861 1.04 6.95e-271
104 12 Ex4 Excitatory neurons all TSPYL1 7259 12382 0.65 5.66e-269
104 12 Ex4 Excitatory neurons all PRNP 5621 9449 0.55 1.65e-254
104 12 Ex4 Excitatory neurons all CUX2 23316 19347 0.72 1.12e-246
104 12 Ex4 Excitatory neurons all SYNPO 11346 30672 1.07 8.33e-242
104 12 Ex4 Excitatory neurons all VSTM2A 222008 28499 1.08 5.51e-240
104 12 Ex4 Excitatory neurons all BSG 682 1116 0.82 1.35e-237
104 12 Ex4 Excitatory neurons all MTRNR2L12 100463498 37169 1.28 3.85e-235
104 12 Ex4 Excitatory neurons all NRGN 4900 8000 0.59 7.3e-234
104 12 Ex4 Excitatory neurons all LRATD1 151354 20743 1.19 4.9e-231
104 12 Ex4 Excitatory neurons all ACTB 60 132 0.58 3.88e-227
104 12 Ex4 Excitatory neurons all GLIS3 169792 28510 1.05 1.31e-224
104 12 Ex4 Excitatory neurons all HAPLN4 404037 31357 1.36 8.66e-222
104 12 Ex4 Excitatory neurons all FLRT2 23768 3761 0.57 1.73e-211
104 12 Ex4 Excitatory neurons all SLC17A7 57030 16704 0.61 4.66e-210
104 12 Ex4 Excitatory neurons all FAIM2 23017 17067 0.54 9.1e-209
104 12 Ex4 Excitatory neurons all EPHA6 285220 19296 0.6 1.43e-196
104 12 Ex4 Excitatory neurons all ENC1 8507 3345 0.52 3.15e-195
104 12 Ex4 Excitatory neurons all DGKB 1607 2850 0.5 1.61e-192
104 12 Ex4 Excitatory neurons all MAST3 23031 19036 0.79 8.04e-185
104 12 Ex4 Excitatory neurons all PPP2R1A 5518 9302 0.7 6.75e-179
104 12 Ex4 Excitatory neurons all MTRNR2L8 100463486 37165 1.36 2.17e-178
104 12 Ex4 Excitatory neurons all SYN1 6853 11494 0.63 8.93e-178
104 12 Ex4 Excitatory neurons all RP11-618P17.4 NULL 1.03 1.31e-173
104 12 Ex4 Excitatory neurons all RFX3 5991 9984 0.66 8.16e-171
104 12 Ex4 Excitatory neurons all GDI1 2664 4226 0.59 1.06e-168
104 12 Ex4 Excitatory neurons all TESPA1 9840 29109 0.65 5.1e-166
104 12 Ex4 Excitatory neurons all LAMA2 3908 6482 1.2 3e-164
104 12 Ex4 Excitatory neurons all CHD5 26038 16816 0.57 5.9e-161
104 12 Ex4 Excitatory neurons all PDE7B 27115 8792 0.9 4.9e-159
104 12 Ex4 Excitatory neurons all JUND 3727 6206 0.75 3.27e-158
104 12 Ex4 Excitatory neurons all TAFA1 407738 21587 0.54 1.63e-157
104 12 Ex4 Excitatory neurons all ELK1 2002 3321 0.95 3.46e-141
104 12 Ex4 Excitatory neurons all NRXN2 9379 8009 0.64 2.89e-139
104 12 Ex4 Excitatory neurons all CADM3 57863 17601 0.67 1.04e-137
104 12 Ex4 Excitatory neurons all RASD1 51655 15828 0.87 1.25e-134
104 12 Ex4 Excitatory neurons all NPTN 27020 17867 0.56 7.01e-134
104 12 Ex4 Excitatory neurons all MAPK8IP2 23542 6883 0.86 3.48e-133
104 12 Ex4 Excitatory neurons all EEF1A2 1917 3192 0.94 3.07e-131
104 12 Ex4 Excitatory neurons all ITPKA 3706 6178 0.89 6.07e-130
104 12 Ex4 Excitatory neurons all PSD 5662 9507 0.8 4.22e-128
104 12 Ex4 Excitatory neurons all SGCD 6444 10807 0.63 1.26e-126
104 12 Ex4 Excitatory neurons all UBE2M 9040 12491 1 1.34e-123
104 12 Ex4 Excitatory neurons all COL5A2 1290 2210 0.94 6.58e-123
104 12 Ex4 Excitatory neurons all LZTS1 11178 13861 0.91 2e-122
104 12 Ex4 Excitatory neurons all HDAC9 9734 14065 0.57 2.14e-122
104 12 Ex4 Excitatory neurons all PDZD4 57595 21167 0.86 6.05e-122
104 12 Ex4 Excitatory neurons all H1FX 8971 4722 0.8 4.53e-121
104 12 Ex4 Excitatory neurons all CLIP3 25999 24314 0.62 4.1e-120
104 12 Ex4 Excitatory neurons all NCDN 23154 17597 1.07 5.2e-120
104 12 Ex4 Excitatory neurons all CPLX2 10814 2310 0.64 1.85e-119
104 12 Ex4 Excitatory neurons all ARHGEF25 115557 30275 1.02 7.69e-119
104 12 Ex4 Excitatory neurons all SNPH 9751 15931 0.74 7.06e-118
104 12 Ex4 Excitatory neurons all SIRPA 140885 9662 0.53 7.9e-118
104 12 Ex4 Excitatory neurons all TSPYL4 23270 21559 0.65 9.37e-115
104 12 Ex4 Excitatory neurons all GNB2 2783 4398 0.91 4.26e-114
104 12 Ex4 Excitatory neurons all PCDH8 5100 8660 1.05 1.6e-113
104 12 Ex4 Excitatory neurons all MTPN 136319 15667 0.68 4.66e-112
104 12 Ex4 Excitatory neurons all CDIP1 29965 13234 0.63 6.05e-110
104 12 Ex4 Excitatory neurons all BAIAP2 10458 947 0.52 2.82e-108
104 12 Ex4 Excitatory neurons all ZBTB18 10472 13030 0.68 4.18e-108
104 12 Ex4 Excitatory neurons all SERINC3 10955 11699 0.5 2.14e-103
104 12 Ex4 Excitatory neurons all NCS1 23413 3953 0.69 1.45e-101
104 12 Ex4 Excitatory neurons all RNF208 727800 25420 0.89 2.47e-100
104 12 Ex4 Excitatory neurons all BAIAP3 8938 948 0.99 5.8e-99
104 12 Ex4 Excitatory neurons all RANGAP1 5905 9854 0.86 4.12e-98
104 12 Ex4 Excitatory neurons all BTBD3 22903 15854 0.75 2.41e-97
104 12 Ex4 Excitatory neurons all DNAJB2 3300 5228 0.65 3.73e-97
104 12 Ex4 Excitatory neurons all ACTN4 81 166 0.65 4.04e-96
104 12 Ex4 Excitatory neurons all GULP1 51454 18649 0.66 4.79e-96
104 12 Ex4 Excitatory neurons all HSPB1 3315 5246 0.98 4.91e-96
104 12 Ex4 Excitatory neurons all ZBTB7A 51341 18078 0.63 1.33e-94
104 12 Ex4 Excitatory neurons all INA 9118 6057 0.64 2.16e-94
104 12 Ex4 Excitatory neurons all PRAG1 157285 25438 1.02 4.97e-94
104 12 Ex4 Excitatory neurons all FKBP5 2289 3721 0.91 4.49e-93
104 12 Ex4 Excitatory neurons all SMAD2 4087 6768 0.93 1.32e-89
104 12 Ex4 Excitatory neurons all NAT8L 339983 26742 0.64 4.49e-88
104 12 Ex4 Excitatory neurons all SORT1 6272 11186 0.52 6.6e-85
104 12 Ex4 Excitatory neurons all PTPRN 5798 9676 0.59 4.21e-84
104 12 Ex4 Excitatory neurons all PIP4K2B 8396 8998 0.55 7.13e-83
104 12 Ex4 Excitatory neurons all C1orf115 79762 25873 0.69 2.3e-82
104 12 Ex4 Excitatory neurons all RUNDC3A 10900 16984 0.58 4.9e-82
104 12 Ex4 Excitatory neurons all MBOAT7 79143 15505 0.7 1.68e-80
104 12 Ex4 Excitatory neurons all NPTXR 23467 7954 0.62 2.62e-79
104 12 Ex4 Excitatory neurons all PLEKHA2 59339 14336 0.88 7.41e-79
104 12 Ex4 Excitatory neurons all VSTM2L 128434 16096 0.74 2.46e-78
104 12 Ex4 Excitatory neurons all HOPX 84525 24961 0.51 2.69e-78
104 12 Ex4 Excitatory neurons all TAFA5 25817 21592 0.63 3.34e-77
104 12 Ex4 Excitatory neurons all WDR82 80335 28826 0.5 5.48e-77
104 12 Ex4 Excitatory neurons all CTBP1 1487 2494 0.63 4.6e-76
104 12 Ex4 Excitatory neurons all MAPK8IP1 9479 6882 0.9 5.62e-76
104 12 Ex4 Excitatory neurons all PTPA 5524 9308 0.74 6.87e-76
104 12 Ex4 Excitatory neurons all CYP46A1 10858 2641 0.6 7.75e-74
104 12 Ex4 Excitatory neurons all TPPP 11076 24164 0.5 3.05e-72
104 12 Ex4 Excitatory neurons all GIT1 28964 4272 0.7 7.63e-72
104 12 Ex4 Excitatory neurons all STXBP6 29091 19666 0.62 8.63e-71
104 12 Ex4 Excitatory neurons all LRRC4B 94030 25042 0.63 8.88e-71
104 12 Ex4 Excitatory neurons all SH3GLB2 56904 10834 0.72 8.99e-71
104 12 Ex4 Excitatory neurons all LZTS3 9762 30139 0.58 1.27e-70
104 12 Ex4 Excitatory neurons all HPCAL1 3241 5145 0.61 1.31e-70
104 12 Ex4 Excitatory neurons all PTPRF 5792 9670 0.69 1.01e-69
104 12 Ex4 Excitatory neurons all DYNLL2 140735 24596 0.53 4.61e-68
104 12 Ex4 Excitatory neurons all ADAP1 11033 16486 0.92 9.05e-68
104 12 Ex4 Excitatory neurons all MAP2K2 5605 6842 0.81 6.18e-67
104 12 Ex4 Excitatory neurons all DGCR2 9993 2845 0.58 1.06e-66
104 12 Ex4 Excitatory neurons all PABPN1 8106 8565 0.62 4.57e-66
104 12 Ex4 Excitatory neurons all TNFRSF25 8718 11910 0.8 1.94e-65
104 12 Ex4 Excitatory neurons all PEA15 8682 8822 0.52 4.78e-65
104 12 Ex4 Excitatory neurons all TMEM127 55654 26038 0.87 7.84e-65
104 12 Ex4 Excitatory neurons all APBB1 322 581 0.54 9.56e-65
104 12 Ex4 Excitatory neurons all ADGRB1 575 943 0.74 4.49e-64
104 12 Ex4 Excitatory neurons all ADGRB2 576 944 0.6 1.13e-63
104 12 Ex4 Excitatory neurons all CAPNS1 826 1481 0.75 9.65e-62
104 12 Ex4 Excitatory neurons all LTBP3 4054 6716 0.75 1.25e-61
104 12 Ex4 Excitatory neurons all PYGB 5834 9723 0.75 1.41e-59
104 12 Ex4 Excitatory neurons all MAPK3 5595 6877 0.71 7.46e-59
104 12 Ex4 Excitatory neurons all RABL6 55684 24703 0.64 8.61e-59
104 12 Ex4 Excitatory neurons all BIN1 274 1052 0.5 1.86e-58
104 12 Ex4 Excitatory neurons all CAMTA2 23125 18807 0.65 3.76e-58
104 12 Ex4 Excitatory neurons all KCNIP2 30819 15522 0.62 1.56e-57
104 12 Ex4 Excitatory neurons all NBL1 4681 7650 0.72 1.15e-56
104 12 Ex4 Excitatory neurons all SUN2 25777 14210 0.81 8.06e-56
104 12 Ex4 Excitatory neurons all YJEFN3 374887 24785 0.8 1.06e-55
104 12 Ex4 Excitatory neurons all PLXNA1 5361 9099 0.8 1.08e-55
104 12 Ex4 Excitatory neurons all SPOCK3 50859 13565 0.61 3.78e-55
104 12 Ex4 Excitatory neurons all CEBPD 1052 1835 0.75 1.17e-54
104 12 Ex4 Excitatory neurons all KCTD2 23510 21294 0.76 2.46e-54
104 12 Ex4 Excitatory neurons all KLHL2 11275 6353 0.51 6.73e-54
104 12 Ex4 Excitatory neurons all TYRO3 7301 12446 0.54 1.14e-53
104 12 Ex4 Excitatory neurons all LMTK3 114783 19295 0.65 2.5e-53
104 12 Ex4 Excitatory neurons all KCNA2 3737 6220 0.73 2.63e-53
104 12 Ex4 Excitatory neurons all FBXO44 93611 24847 0.61 3.99e-53
104 12 Ex4 Excitatory neurons all SCN1B 6324 10586 0.76 1.06e-52
104 12 Ex4 Excitatory neurons all SLC24A4 123041 10978 0.78 1.2e-51
104 12 Ex4 Excitatory neurons all NSMF 26012 29843 0.63 2.13e-51
104 12 Ex4 Excitatory neurons all CLCN7 1186 2025 0.8 2.5e-51
104 12 Ex4 Excitatory neurons all MT3 4504 7408 0.6 8.44e-51
104 12 Ex4 Excitatory neurons all MAP1S 55201 15715 0.79 2.85e-50
104 12 Ex4 Excitatory neurons all ATN1 1822 3033 0.56 3.17e-50
104 12 Ex4 Excitatory neurons all PLPPR2 64748 29566 0.81 1.9e-49
104 12 Ex4 Excitatory neurons all INO80D 54891 25997 0.61 3.79e-49
104 12 Ex4 Excitatory neurons all UBTF 7343 12511 0.7 7.04e-49
104 12 Ex4 Excitatory neurons all WIPF3 644150 22004 0.5 1.97e-48
104 12 Ex4 Excitatory neurons all USF2 7392 12594 0.74 7.3e-48
104 12 Ex4 Excitatory neurons all SERPINE2 5270 8951 0.68 1.2e-47
104 12 Ex4 Excitatory neurons all GPC1 2817 4449 0.59 4.38e-47
104 12 Ex4 Excitatory neurons all PPP1R9B 84687 9298 0.64 7.1e-47
104 12 Ex4 Excitatory neurons all AGAP2 116986 16921 0.64 3.89e-46
104 12 Ex4 Excitatory neurons all BRSK2 9024 11405 0.51 7.5e-46
104 12 Ex4 Excitatory neurons all SLC38A11 151258 26836 0.61 7.93e-46
104 12 Ex4 Excitatory neurons all ATXN7L3 56970 25416 0.6 1.39e-45
104 12 Ex4 Excitatory neurons all DLG4 1742 2903 0.53 4.15e-45
104 12 Ex4 Excitatory neurons all PIP5K1B 8395 8995 0.64 1.67e-44
104 12 Ex4 Excitatory neurons all SYT13 57586 14962 0.55 3.46e-44
104 12 Ex4 Excitatory neurons all GRK2 156 289 0.68 4.83e-44
104 12 Ex4 Excitatory neurons all BCAR1 9564 971 0.68 9.22e-43
104 12 Ex4 Excitatory neurons all PDK2 5164 8810 0.76 3.17e-42
104 12 Ex4 Excitatory neurons all KCNJ4 3761 6265 0.67 1.29e-41
104 12 Ex4 Excitatory neurons all SDCBP 6386 10662 0.6 1.46e-41
104 12 Ex4 Excitatory neurons all CRIP2 1397 2361 0.64 1.52e-41
104 12 Ex4 Excitatory neurons all PPP4R4 57718 23788 0.57 2.69e-41
104 12 Ex4 Excitatory neurons all PRKACA 5566 9380 0.62 3.72e-41
104 12 Ex4 Excitatory neurons all DDN 23109 24458 0.78 5.72e-41
104 12 Ex4 Excitatory neurons all ZMYM3 9203 13054 0.59 1.87e-40
104 12 Ex4 Excitatory neurons all PLEC 5339 9069 0.5 2.91e-40
104 12 Ex4 Excitatory neurons all GALNT9 50614 4131 0.67 6.68e-40
104 12 Ex4 Excitatory neurons all B4GALNT4 338707 26315 0.63 4.72e-39
104 12 Ex4 Excitatory neurons all GOLGA7B 401647 31668 0.68 3.27e-38
104 12 Ex4 Excitatory neurons all DIRAS1 148252 19127 0.52 6.39e-38
104 12 Ex4 Excitatory neurons all INTS1 26173 24555 0.74 6.21e-37
104 12 Ex4 Excitatory neurons all CHST1 8534 1969 0.54 7.82e-37
104 12 Ex4 Excitatory neurons all CDK5R2 8941 1776 0.62 1.82e-36
104 12 Ex4 Excitatory neurons all SNN 8303 11149 0.5 2.3e-36
104 12 Ex4 Excitatory neurons all PRRT1 80863 13943 0.51 7.84e-36
104 12 Ex4 Excitatory neurons all CTXN1 404217 31108 0.71 1.26e-35
104 12 Ex4 Excitatory neurons all GLRA3 8001 4328 0.56 2.22e-35
104 12 Ex4 Excitatory neurons all HYOU1 10525 16931 0.64 2.45e-34
104 12 Ex4 Excitatory neurons all TNPO2 30000 19998 0.5 5.78e-34
104 12 Ex4 Excitatory neurons all RTN4R 65078 18601 0.66 7.49e-34
104 12 Ex4 Excitatory neurons all ARFGAP1 55738 15852 0.55 1.21e-33
104 12 Ex4 Excitatory neurons all ABCA2 20 32 0.61 1.37e-33
104 12 Ex4 Excitatory neurons all VPS4A 27183 13488 0.63 6.98e-33
104 12 Ex4 Excitatory neurons all PNMA3 29944 18742 0.59 1.01e-32
104 12 Ex4 Excitatory neurons all EIF5A 1984 3300 0.5 1.16e-32
104 12 Ex4 Excitatory neurons all ETS2 2114 3489 0.56 1.52e-32
104 12 Ex4 Excitatory neurons all BRSK1 84446 18994 0.56 1.59e-31
104 12 Ex4 Excitatory neurons all CRLF1 9244 2364 0.51 1.9e-31
104 12 Ex4 Excitatory neurons all CHRM1 1128 1950 0.66 4.01e-31
104 12 Ex4 Excitatory neurons all LGI3 203190 18711 0.56 4.55e-31
104 12 Ex4 Excitatory neurons all HSPA13 6782 11375 0.51 4.07e-30
104 12 Ex4 Excitatory neurons all TMEM181 57583 20958 0.52 1.05e-29
104 12 Ex4 Excitatory neurons all DOC2A 8448 2985 0.53 1.16e-29
104 12 Ex4 Excitatory neurons all TMEM63B 55362 17735 0.71 2.15e-29
104 12 Ex4 Excitatory neurons all TMEM9 252839 18823 0.52 2.39e-29
104 12 Ex4 Excitatory neurons all GPD1L 23171 28956 0.59 2.43e-29
104 12 Ex4 Excitatory neurons all SIN3B 23309 19354 0.51 2.78e-28
104 12 Ex4 Excitatory neurons all PFKL 5211 8876 0.67 3.43e-28
104 12 Ex4 Excitatory neurons all KLC2 64837 20716 0.53 3.7e-28
104 12 Ex4 Excitatory neurons all PPFIA3 8541 9247 0.56 8.95e-28
104 12 Ex4 Excitatory neurons all RAB11B 9230 9761 0.51 1.4e-26
104 12 Ex4 Excitatory neurons all SEMA6B 10501 10739 0.63 2.49e-26
104 12 Ex4 Excitatory neurons all ATG13 9776 29091 0.53 1.04e-25
104 12 Ex4 Excitatory neurons all CHD4 1108 1919 0.5 1.67e-25
104 12 Ex4 Excitatory neurons all SSBP4 170463 15676 0.59 2.2e-25
104 12 Ex4 Excitatory neurons all UBXN6 80700 14928 0.68 4.57e-25
104 12 Ex4 Excitatory neurons all LRP1 4035 6692 0.5 7.01e-25
104 12 Ex4 Excitatory neurons all CARM1 10498 23393 0.53 3.86e-24
104 12 Ex4 Excitatory neurons all PER1 5187 8845 0.6 5.21e-24
104 12 Ex4 Excitatory neurons all TCERG1L 256536 23533 0.54 6.39e-24
104 12 Ex4 Excitatory neurons all CELF3 11189 11967 0.54 9.53e-24
104 12 Ex4 Excitatory neurons all EGFL7 51162 20594 0.52 4.3e-22
104 12 Ex4 Excitatory neurons all PPARGC1A 10891 9237 0.51 6.65e-22
104 12 Ex4 Excitatory neurons all MATK 4145 6906 0.56 7.22e-22
104 12 Ex4 Excitatory neurons all MOB1B 92597 29801 0.59 1.02e-21
104 12 Ex4 Excitatory neurons all FSCN1 6624 11148 0.52 1.08e-21
104 12 Ex4 Excitatory neurons all ZMIZ2 83637 22229 0.61 1.28e-21
104 12 Ex4 Excitatory neurons all SH3GL1 6455 10830 0.55 1.56e-21
104 12 Ex4 Excitatory neurons all C2orf72 257407 27418 0.54 1.86e-21
104 12 Ex4 Excitatory neurons all DHCR24 1718 2859 0.55 3.07e-21
104 12 Ex4 Excitatory neurons all FAM131B 9715 22202 0.53 7.42e-20
104 12 Ex4 Excitatory neurons all TEF 7008 11722 0.5 1.53e-18
104 12 Ex4 Excitatory neurons all FSD1 79187 13745 0.52 1.51e-14
104 12 Ex4 Excitatory neurons all KCNV1 27012 18861 0.5 1.19e-13
104 12 Ex4 Excitatory neurons all FBXO41 150726 29409 0.5 2.62e-12