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Fly alphafold multimer predicting protein-protein interactions

FlyPredictome offers computationally predicted protein-protein interactions through AlphaFold-Multimer. Introducing the Local Interaction Score (LIS) and Area (LIA), our platform enriches the analysis of protein complexes by providing measures of interaction strength and contact area, based on the predicted aligned error (PAE). These metrics enhance the detection of direct interactions, advancing computational approaches in PPI network identification.

Read our full study here: Enhanced Protein-Protein Interaction Discovery via AlphaFold-Multimer (Kim et al. 2024, ).