| Gene Information |
TRiP Stock Information
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| Symbol: | CCT1 |
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| CG: | CG5374 |
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| FBgn: |
FBgn0003676 |
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| Validation Test Results
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| Driver: | y w; Dmef2.R-Gal4 |
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| Driver BDSC: |
27390 |
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| Contributor(s): |
Perrimon and Randklev, 2013, unpublished data. |
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Phenotype Results:
- Phenotype: Embryonic/L3 lethal
- Penetrance: 100%
- Temperature (°C): 27
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| Driver: | MTD-Gal4 |
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| Driver BDSC: |
31777 |
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| Contributor(s): |
Dong Yan and Ralph Neumuller, 2013 |
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| Reference: |
Yan D et al., 2014   |
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Phenotype Results:
- Phenotype Category: agametic
- Phenotype Antibody Info: a-Spectrin antobody is from DSHB, 3A9; mouse Vasa antibody is from Santa Cruz Biotechnology, d-260,
- Phenotype: no eggs
- Penetrance: 100%
- Temperature (°C): 29
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| Driver: | w; matalpha4-GAL-VP16 |
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| Driver BDSC: |
7063 |
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| Contributor(s): |
Lynn Cooley and Kathleen Ayers, 2013 |
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| Reference: |
Yan D et al., 2014 |
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Phenotype Results:
- Staining info: Alexa 488-phalloidin (Molecular Probes) and DAPI (Molecular Probes)
- Penetrance: 100%
- Ovary Phenotype: early arrest, very small ovaries
- Female Fertility: no eggs
- Temperature (°C): 25
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| Driver: | Act5C-Gal4 |
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| Driver BDSC: |
not annotated |
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| Contributor(s): |
Zeng et al., 2015 |
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| Reference: |
Zeng et al., 2015 |
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Phenotype Results:
- Phenotype: lethal
- Temperature (°C): 25
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Phenotype Results:
- Phenotype Category: Eye phenotype
- Phenotype: small, no eyes
- Penetrance: 80% (total number=20)
- Temperature (°C): 25
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Phenotype Results:
- Phenotype Category: Eye phenotype
- Phenotype: rough, misshapen, small
- Penetrance: 47% (50% of 8 male; 43% of 7 female)
- Temperature (°C): 25
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Phenotype Results:
- Phenotype Category: Mitochondria phenotype
- Phenotype: the average mitochondrial length was shorter than that in the wild type (L < 2 um, P < 0.05)
- Penetrance: 61.25%
- Temperature (°C): 25
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Phenotype Results:
- Phenotype_2: size defective | adult stage, with Scer\GAL4[eya.enh1+E+2]
- Phenotype_1: visible | adult stage, with Scer\GAL4[eya.enh1+E+2]
- Phenotype: eye, with Scer\GAL4[eya.enh1+E+2]
- FlyBase Allele ID: FBal0257323
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| Driver: | Pph13-GAL4 |
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| Driver BDSC: |
not annotated |
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| Contributor(s): |
Andrew Zelhof |
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Phenotype Results:
- Phenotype: The presence of a deep psuedopupil in retina: Normal
- Temperature (°C): 25
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Phenotype Results:
- Phenotype: GFP fluorescence? lymph gland: Decreased/missing
- Temperature (°C): 29C
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Phenotype Results:
- Phenotype: GFP fluorescence? circulation: Increased +
- Temperature (°C): 29C
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Phenotype Results:
- Phenotype: GFP fluorescence ?heart tube: Decreased / missing
- Temperature (°C): 29C
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| Driver: | Hml[D]-GAL4 |
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| Driver BDSC: |
not annotated |
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| Contributor(s): |
Utpal Banerjee |
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| Reference: |
Evans CJ, et al., 2021 |
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Phenotype Results:
- Phenotype: Circulating Hml[D]-DsRed expression: change in reporter expression
- Temperature (°C): 29C
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| Driver: | Pph13-GAL4 |
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| Driver BDSC: |
not annotated |
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| Contributor(s): |
Andrew C Zelhof |
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| Reference: |
Rylee J, et al., 2022 |
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Phenotype Results:
- Phenotype: Photoreceptor/Deep Pseudopupil (DPP) Phenotype: No Effect
- Temperature (°C): 25C
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Community Input
(asterisk indicates required
field)
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Contributor*:
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Driver*: |
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Driver BDSC: |
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Temperature*:
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°C |
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qPCR data: |
% Remaining after knockdown |
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Phenotype? |
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Contributor
Email*: |
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