iproteinDB -integrated protein database DB

Home // Protein // FBpp0075122 (D.mel)

Listed below are the best predicted orthologs in human (hs) and five other major model organisms: mouse (mm), rat (rn), frog (xt), zebrafish (dr), and worm (ce). An ortholog is considered "best" if it has a score of 3 or higher, based on the DIOPT scoring algorithms. Some organisms may have more than one prediction.

Index	RefSeq	NCBI Gene ID	Symbol	Species Gene ID	Species Database	DIOPT Score	Best Score?	Best Reverse Score?	Confidence
ag1	XP_061501928.1	1278402	spd-2	AGAMI1_002268	VectorBase	9	Yes	Yes	High
hs1	XP_005258164.1	55125	CEP192	25515	HGNC	3	Yes	Yes	High
mm1	XP_006526304.1	70799	Cep192	1918049	MGI	3	Yes	Yes	High
xt1	XP_004915311.2	100493118	cep192	XB-GENE-5880666	Xenbase	3	Yes	Yes	High
dr1	XP_009290386.2	565521	cep192	ZDB-GENE-100922-163	ZFIN	4	Yes	Yes	High

Index	Region	Domain	Description	External Link
dm1	..
hs1	201..251	Plk4BD_Cep192	Plk4-binding domain found in centrosomal protein of 192 kDa (Cep192) and similar proteins; cd21856	CDD:439317
hs1	1661..1724	ASH	Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin; pfam15780	CDD:464865
mm1	193..242	Plk4BD_Cep192	Plk4-binding domain found in centrosomal protein of 192 kDa (Cep192) and similar proteins; cd21856	CDD:439317
mm1	<1636..1703	ASH	Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin; pfam15780	CDD:464865
xt1	179..228	Plk4BD_Cep192	Plk4-binding domain found in centrosomal protein of 192 kDa (Cep192) and similar proteins; cd21856	CDD:439317
xt1	<1778..1846	ASH	Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin; pfam15780	CDD:464865

Fly: No UniProt information found.

Index	Uniprot ID	Locations

The following table depicts conserved S/T/Y sites in fly with 50% average identity across a 11-aa window. These sites will be bolded in the MSA results below. To look at all sites (including windows with lower identities), click here.

Position	±5-aa Window	Antibody Available?	Average Identity
800	--IPL YGYGGS	No	0.64
802	IPLYG YGGSAS	No	0.64

Shown below are antibodies provided by Cell Signaling Technology that may or may not target fly at the conserved S/T/Y positions listed above. Note that these antibodies are subject for testing.