Results

Rank Table

id Rank Protein 1 Protein 2 fbgn1 fbgn2 ncbi_gene_id1 ncbi_gene_id2 Symbol 1 Symbol 2 protein_1_size protein_2_size iLIS LIS (AB) LIS (BA) LIS LIA (AB) LIA (BA) LIA LIR (A) LIR (B) LIR LIpLDDT (A) LIpLDDT (B) LIpLDDT cLIS (AB) cLIS (BA) cLIS cLIA (AB) cLIA (BA) cLIA cLIR (A) cLIR (B) cLIR cLIpLDDT (A) cLIpLDDT (B) cLIpLDDT LIR Indice A LIR Indice B cLIR Indice A cLIR Indice B ipTM Confidence pae_file_name directory_name output_file_name enrichment_id1 enrichment_id2 pLDDT pTM Len A Len B
select 1 upd1 dome FBgn0004956 FBgn0043903 32813 32976 upd1 dome full full 0.529 0.408 0.36 0.384 37919 41293 79212 223 325 548 76.198 88.62 83.565 0.764 0.694 0.729 44 45 89 21 24 45 81.018 80.272 80.62 ["77-105","114-238","255-281","288-327"] ["20-329","356-366","368","408"] ["79-80","149-154","156-157","200-204","272","274","277","298"] ["23-27","57","59","103","105","107-108","110-113","115","152","154","173-176"] 0.57 0.544 upd1___dome_scores_rank_001_alphafold2_multimer_v3_model_4_seed_000.json SET_69 59.343 0.44 413 1282
select 2 upd1 dome FBgn0004956 FBgn0043903 32813 32976 upd1 dome full full 0.435 0.32 0.277 0.298 20976 23764 44740 201 258 459 78.365 88.258 83.926 0.634 0.633 0.633 44 41 85 18 23 41 84.812 79.67 81.927 ["82-104","117-233","258-281","290-324"] ["20-186","190-227","231","233","242-246","249-250","252-254","257-264","285-289","292","297-308","311-323"] ["150-154","156-157","200-204","272","274","277","298"] ["23-27","60","103","105","107-108","110-113","115","152","154-155","173","175-176"] 0.52 0.498 upd1___dome_scores_rank_002_alphafold2_multimer_v3_model_1_seed_000.json SET_69 59.05 0.41 413 1282
select 3 upd1 dome FBgn0004956 FBgn0043903 32813 32976 upd1 dome full full 0.398 0.295 0.25 0.272 20363 23253 43616 197 270 467 77.483 88.158 83.655 0.608 0.558 0.583 43 42 85 20 24 44 80.277 80.22 80.246 ["80-101","117-230","232","258-280","290-324"] ["21-187","189-227","229-234","240-250","252-264","286-289","292","294","297-309","311-323"] ["80","149-154","156-157","200-204","272","274","277","298"] ["23-27","59","103","105","107-108","110-113","115","152","154-155","173-176"] 0.51 0.492 upd1___dome_scores_rank_003_alphafold2_multimer_v3_model_5_seed_000.json SET_69 58.379 0.42 413 1282
select 4 upd1 dome FBgn0004956 FBgn0043903 32813 32976 upd1 dome full full 0.375 0.274 0.24 0.257 18817 21285 40102 196 257 453 77.041 88.162 83.35 0.583 0.51 0.546 45 44 89 20 23 43 81.814 80.034 80.862 ["80-100","118-232","259-280","289-324"] ["21-187","189-190","193-227","231","233","241-246","249","252-253","257-264","271","287-289","292","297-323"] ["149-154","156-157","200-204","272","274","277-278","298"] ["23-27","59","103","105","107-108","110-113","115","152","154-155","173","175-176"] 0.51 0.494 upd1___dome_scores_rank_004_alphafold2_multimer_v3_model_3_seed_000.json SET_69 58.663 0.43 413 1282
select 5 upd1 dome FBgn0004956 FBgn0043903 32813 32976 upd1 dome full full 0.127 0.076 0.096 0.086 768 3737 4505 137 175 312 79.392 88.908 84.729 0.177 0.2 0.188 35 31 66 22 12 34 71.161 76.87 73.176 ["81-83","92-135","158","160-161","170-191","193-196","207-208","210-234","259","261-268","270-271","273","300-319"] ["37-39","45","47","99","101","103-105","115","117-177","179-227","231","233","240-247","250-253","257-265","269","286-289","292","297-308","312-322"] ["100-110","112","126","130-131","216","219-220","223","227"] ["165-170","187-188","191-192"] 0.42 0.424 upd1___dome_scores_rank_005_alphafold2_multimer_v3_model_2_seed_000.json SET_69 59.204 0.44 413 1282

Predicted Aligned Error Map

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upd1dome
upd1___dome_pae.png

Interaction Interface

Protein A - FBgn0004956 /   upd1

Highlights Show Interactions


1     MARPLLLLLP ILLVLLLAAQ LPHLAEGRST TSSGGLTVID SERLRIRTTS STASAQHPNQ GTIPASAASP RKRHRKRNSN
81    WIDYRNFDEN TTALEWANPC GGNYHPSAGD RFNRQRPRQS FNQLKRHAFR EYRSLNSSQD SAIDIRNMTM WSLHTHNYKF
161   LPKLKPNSTI ALKRWYRNMQ TYVASFAYLR RQQIRWDQRS ITRESSTARE LRELLLSSRR ILCELETAVN QTQSPRQKQR
241   RSGAAVTAVG GTTMLGQQLP QISRLEMNKR LKLRSKTSGP GMGGAASSAS MAAGEADSID MRFVKHHYYD FLRTMYQLLR
321   RDGKRVRSRP RKHHKKQQRS QKKLLQQQQQ LADQLEQRWR SSTLNGKEFN EVSKPVAGGA AGVADVAGVS GGGSNQFARG
401   RRGKRQSKRV QRT

Protein B - FBgn0043903 / dome

Highlights Show Interactions


1     MVAQEQLVLL LMLLAGCRGG ANAILDPGWV IPSKVEQLIG GDFNLSCTLN EDYFNGKSAE DCPVEKLYFT GGGRVYRDSK
81    HIRILNNTTI LFSDTNAVEQ ENDYHCMCDE YVINKSKVYV GTRPLLVRDF NCLDYDFQFM VCNFTQPPNT VITKYNISYN
161   TNNDWRYSNT LDCNFDSAPV VTCNLTDDNY KRFSETFYFR LSISNALGHE TQPITINHFE RLVPARPGQN LTLLNRTESS
241   VCLSWEMPRR SNYNRGLVWQ VRVTPQNFEP ITRPSWRNHT LTIKDTLCLT ELPFAGYNYT LRVRVRANQN NTLWSEPMIY
321   AFATAPAPPR RPPRVTYGSF YVYSSEKAMR FYWEPLEEHE LNGPDFRYSI SEYRINGTAV DPGLIKVESN SAMIDHWSMS
401   AVHHFLIRSS NSQGLSVNAT PMTIGPISNR DFKVREPRNI RSVYHPTNKS YTLSWDPPSD QRELQNYTVF WCVPKPGLQS
481   ECEGSIRFAE VASGLHHFTT SPDQLLTLHM AVSANYQSHN TGLHWAICSS DKKDDLAKME PSIDVATSTS LTVSWSERVC
561   AVILAGYNLT YCQRSAGRPD NCTTVTIDRY TNKHVIQNLV PYTDYSVKML MYSDSRVSKY SDELVNRTGE AAPSQPRELQ
641   LIRVTSDSVE LAWKPPLLAN GVVRAYEGTF RSLHDNVTDT FRVSASADEL VNNEKPITYR LGNLTAFTKY EISVRARTVY
721   PSEPSNVILF STAIGVPSPP QLYVINNPDQ SSRLDWEPPR TPAGRIDFYE ISLRDNNASC LTSTILPGRN LSYVMATPRC
801   TSHNPFQLAV RAINVEQHPQ LNGADAAEGA VLLMSTNGKG CEARTDALGE EERLQFEAYA ANMTAYRLYR SDWGIYGFIC
881   TPDTHSVKAM YQTIEVTVAI LVLGVIFYLV YKKYRKMSDI GLVLPQGIME TMKKPIDMGG LGLGLGPDSS VSGGIVCTRV
961   DDSPPYTPQD LPHDFSSCGS ESSKLLLRTA SSSGGGGCVD RDGYDDNHET GPISAVGPPT SYLAMRHGLL VQNDRERERE
1041  RDREQERERE QQQQQRESEM DREQSCTNGY IKPTQMKSWG GNGPSDNDHT FSVPSTAMTA PMSQPLSQIP LSGYVPVPIP
1121  QSRFNPAPVQ PFGSPAVPSA ATAAAASTFF PPAHLLNMDN YVQASDLHKL KPLVAAPLSQ TGGPAFAGSS PATSPPLQLP
1201  PVHAASPAAA TPKMADIGYT TMEQLQLTGL IKPPLAATVG SPTHAAGGAP GGGNQHSRLQ PQINGYVTPQ DLNAMAHNRH
1281  VL
upd1___dome_unrelaxed_rank_001_alphafold2_multimer_v3_model_4_seed_000.pdb
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Protein A: FBgn0004956 /   upd1

Contact Residues Color:

Local Residues Color:

Strand A Color:


Protein B: FBgn0043903 /   dome

Contact Residues Color:

Local Residues Color:

Strand B Color:

Predicted Protein Localization

FBgn0004956 /   upd1:
FBgn0043903 /   dome:

UniProt /Protein Details

Flybase ID Uniprot Symbol EBI Alphafold
FBgn0004956 Q9VWW4 upd1 https://www.alphafold.ebi.ac.uk/entry/Q9VWW4
FBgn0004956 O96525 upd1 https://www.alphafold.ebi.ac.uk/entry/O96525
FBgn0004956 Q8MZC7 upd1 https://www.alphafold.ebi.ac.uk/entry/Q8MZC7
FBgn0043903 Q9VWE0 dome https://www.alphafold.ebi.ac.uk/entry/Q9VWE0

cell_line

'modENCODE_mRNA-Seq_cell.B'

Pearson Correlation: 0.09

tissues

modENCODE_mRNA-Seq_tissues

Pearson Correlation: 0.166

treatment

modENCODE_mRNA-Seq_treatments

Pearson Correlation: 0.558

development_stages

modENCODE_mRNA-Seq_U

Pearson Correlation: 0.85

cell_line

'modENCODE_mRNA-Seq_cell.B'

Pearson Correlation: 0.09

tissues

modENCODE_mRNA-Seq_tissues

Pearson Correlation: 0.166

treatment

modENCODE_mRNA-Seq_treatments

Pearson Correlation: 0.558

development_stages

modENCODE_mRNA-Seq_U

Pearson Correlation: 0.85


MIST Interaction Details

- Paper Counts Reference (PMID)
Protein-protein interaction (Fly) 3 10879541,26658615,11825879
Genetic interaction (Fly) 6 12403714,16277982,14668372,20072127,11696329,11825879
Protein-protein interaction (Interologs) 0 N/A
Genetic interaction (Interologs) 0 N/A