Protein Alignment SCARB2 and santa-maria

DIOPT Version :9

• Sequence 1: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_609121.2
• Gene: santa-maria / 34024
• FlyBaseID: FBgn0025697
• Length: 563
• Species: Drosophila melanogaster
• Alignment Length: 434
• Identity: 126/434 - (29%)
• Similarity: 223/434 - (51%)
• Gaps: 31/434 - (7%)

Human    34 DQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGET-PRVEEVGPYTYRELRNK 97
            |..:.|::.|...|..:::|:.||:.:....|.:|.||||:.....| |.:|:||||.:.|..:|
  Fly    42 DWIMHKEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNPEDFGNLSTKPILEQVGPYRFIERPDK 106

Human    98 ANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVL----TVIEWSQVHFLREIIEA 158
            .:|.:.....:::......:.|:...|.|... |.|.|||...|    |...|..|.  |.:::.
  Fly   107 VDIHWHPENASVTYRRRSLFYFDAAGSNGSLD-DEITTLNAVALSAAATAKYWPPVK--RSLVDV 168

Human   159 MLKAYQQKLFVTHTVDELLW-GYKDEILSL---IHVFRPDIS-PY--FGLFYEKNGTND--GDYV 214
            .||.|..::.|..::||||: ||.|.::.:   :.:|..::. |:  ||.||.:||:.|  |.:.
  Fly   169 GLKMYGAEMSVQKSIDELLFTGYNDAMIDVAMAMPIFGDEVKVPFDKFGWFYTRNGSADLTGVFN 233

Human   215 FLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITK-DEVLYVFPSDFCRSVY 278
            ..||.|......::..||.:.:..:: ...|.|.||:.|: |.|...| .:.:.:|..|.||::.
  Fly   234 VFTGADQLAKLGQMHSWNYQENTGFF-DSYCGMTNGSAGE-FQPQHLKPGDSVGLFTPDMCRTIP 296

Human   279 ITFSDYESVQGLPAFRYK-VPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHF 342
            :.:.:...::||..:::. .|..:...|......|...|.|:.|||:|:|.|:.|:|:.||:|||
  Fly   297 LDYVETVDIEGLEGYKFSGGPRSVDNGTQYPENLCFCGGQCVPSGVMNISSCRFGSPVFMSYPHF 361

Human   343 YQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFP 407
            :.||..:...:||:.|||:|||.::.:.|.|||.|:.|.|||:|:.|:.:........|..:.||
  Fly   362 FNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVAARFQVNMLVEPIQGISLYTGIPRIFFP 426

Human   408 VMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGL 451
            :::..:.|.|..:.|.:||.          :|.::::..:|.|:
  Fly   427 LVWFEQKVRITPDMADQLKV----------LPIVMLSGHIFAGI 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	126/434 (29%)
		Important for interaction with GBA	155..191		11/39 (28%)
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	126/434 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930