Protein Alignment COG7 and Cog7

DIOPT Version :8

• Sequence 1: NP_705831.1
• Gene: COG7 / 91949
• HGNCID: 18622
• Length: 770
• Species: Homo sapiens
• Sequence 2: XP_006507762.2
• Gene: Cog7 / 233824
• MGIID: 2685013
• Length: 782
• Species: Mus musculus
• Alignment Length: 782
• Identity: 712/783 (91%)
• Similarity: 739/783 (94%)
• Gaps: 12/783 (2%)

Human     1 MDFSKFLADDFDVKEWINAAFRAGSKEAASGKADGHAATLVMKLQLFIQEVNHAVEETSHQALQN 65
            ||||||||||||||:|||||||||.|:.|:|||||||||||||||||||||||||||||.|||||
Mouse     1 MDFSKFLADDFDVKDWINAAFRAGPKDGAAGKADGHAATLVMKLQLFIQEVNHAVEETSLQALQN 65

Human    66 MPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADK 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 MPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADK 130

Human   131 WSTLSADIEETFKTQDIAVISAKLTGMQNSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAA 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:
Mouse   131 WSTLSADIEETFKTQDIAVISAKLTGMQNSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAS 195

Human   196 FTSQAVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLAAWQELCQSDLSLDRQLTGLYDALLGA 260
            ||||:||||||||||||||||||||||||||||||||||.|||||||||.|||||||||||||||
Mouse   196 FTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLATWQELCQSDLPLDRQLTGLYDALLGA 260

Human   261 WHTQIQWATQVFQKPHEVVMVLLIQTLGALMPSLPSCLSNGVERAGPEQELTRLLEFYDATAHFA 325
            ||||.|||||||:.|||||.||||||||||:||||.|||.||||||||.||||||||||.|||||
Mouse   261 WHTQTQWATQVFKNPHEVVTVLLIQTLGALVPSLPMCLSAGVERAGPELELTRLLEFYDTTAHFA 325

Human   326 KGLEMALLPHLHEHNLVKVTELVDAVYDPYKPYQLKYGDMEESNLLIQMSAVPLEHGEVIDCVQE 390
            |||||||||||.:||||||.|||||||.||||:|||||||||:|||||:||||||||||||||||
Mouse   326 KGLEMALLPHLQDHNLVKVVELVDAVYGPYKPFQLKYGDMEENNLLIQISAVPLEHGEVIDCVQE 390

Human   391 LSHSVNKLFGLASAAVDRCVRFTNGLGTCGLLSALKSLFAKYVSDFTSTLQSIRKKCKLDHIPPN 455
            |||||:|||||||||||||.:|||||||||||:|||||||||||.||:.|||||||||||.||||
Mouse   391 LSHSVHKLFGLASAAVDRCAKFTNGLGTCGLLTALKSLFAKYVSHFTNALQSIRKKCKLDDIPPN 455

Human   456 SLFQEDWTAFQNSIRIIATCGELLRHCGDFEQQLANRILSTAGKYLSDSCSPRSLAGFQESILTD 520
            |||||||||||||:|||||||||||.|||||||||||||||||||||||.|||||||||:|||||
Mouse   456 SLFQEDWTAFQNSVRIIATCGELLRQCGDFEQQLANRILSTAGKYLSDSYSPRSLAGFQDSILTD 520

Human   521 KKNSAKNPWQEYNYLQKDNPAEYASLMEILYTLKEKGSSNHNLLAAPRAALTRLNQQAHQLAFDS 585
            ||:.||||||||||||||||||||||||||||||||||||||||:|.|.||||||||||||||||
Mouse   521 KKSPAKNPWQEYNYLQKDNPAEYASLMEILYTLKEKGSSNHNLLSASRTALTRLNQQAHQLAFDS 585

Human   586 VFLRIKQQLLLISKMDSWNTAGIGETLTDELPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDS 650
            |||||||||||:|:|||||||||||||||:|||||||||||||||||||||||||||||||||||
Mouse   586 VFLRIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDS 650

Human   651 ALELALHAGKLPFPPEQ------------GDELPELDNMADNWLGSIARATMQTYCDAILQIPEL 703
            |||||||||||||||||            ||||||||||||||||||||||||||||.||||||:
Mouse   651 ALELALHAGKLPFPPEQGMCAPPALWELAGDELPELDNMADNWLGSIARATMQTYCDVILQIPEV 715

Human   704 SPHSAKQLATDIDYLINVMDALGLQPSRTLQHIVTLLKTRPEDYRQVSKGLPRRLATTVATMRSV 768
            :|||.||||||||||||||||||||||||||:|..|||.:||:|||||||||||||.||||||.|
Mouse   716 TPHSTKQLATDIDYLINVMDALGLQPSRTLQNIAALLKAKPEEYRQVSKGLPRRLAATVATMRGV 780

Human   769 NY 770
            ||
Mouse   781 NY 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
COG7	NP_705831.1	COG7	2..767	CDD:287200	708/777 (91%)
Cog7	XP_006507762.2	COG7	2..779	CDD:287200	708/777 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C311637050
eggNOG	1	0.900				E1_KOG4182
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H33431
Inparanoid	1	1.050	1414	1.000	Inparanoid score	I3258
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0007671
OrthoInspector	1	1.000				T2455980
orthoMCL	1	0.900				OOG5_131606
Panther	1	1.100			LDO	PTHR21443
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4519
TreeFam	1	0.960
	14	14.290