Protein Alignment CDKL2 and CG6800

DIOPT Version :10

• Sequence 1: XP_047272338.1
• Gene: CDKL2 / 8999
• HGNCID: 1782
• Length: 582
• Species: Homo sapiens
• Sequence 2: NP_650984.1
• Gene: CG6800 / 42562
• FlyBaseID: FBgn0038902
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 104/293 - (35%)
• Similarity: 157/293 - (53%)
• Gaps: 26/293 - (8%)

Human     3 KYENLGLVGEGSYGMVMKC----RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENL 63
            :|:.|..:|||.:|.|.|.    |||:    |||||....:....:....:||||.|:..:.|.:
  Fly     8 RYKMLEKIGEGVHGCVFKAIDLQRNKE----VAIKKVALKNKFGNIALNTLREIKTLQLCKSEYI 68

Human    64 VNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIK 128
            ::::::........||.|:...|:.:.|:...|.|..|.|:|:..|:..||.:.|...::|||||
  Fly    69 LDIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIK 133

Human   129 PENILVSQSGVVKLCDFGFARTLAAPGE--VYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCL 191
            |.|:|:|.:.::|:.|||.||......|  :|:..|:||||||||:|.|..|||..||:||.||:
  Fly   134 PANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCV 198

Human   192 VTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEI-KEREP------L 249
            |.||..|.|||.|.:||:||..|:..||:  ||    .|:.|....  ||:. |.|.|      .
  Fly   199 VAEMLRGVPLFAGTTDIEQLAIIIRTLGS--PR----LNQWPELTS--LPDYSKIRFPNSVGIHW 255

Human   250 ERRYPKLSEVV-IDLAKKCLHIDPDKRPFCAEL 281
            :..:|..:..| |:|....:..:|..|...:|:
  Fly   256 DNLFPSCTHAVEINLVSNLVVYNPKNRLKASEV 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKL2	XP_047272338.1	STKc_CDKL2_3	2..287	CDD:270836	104/293 (35%)
CG6800	NP_650984.1	STKc_CCRK	8..295	CDD:270826	104/293 (35%)