Protein Alignment: IL18RAP and otk

• Sequence 1: NP_003844.1
• Gene: IL18RAP
• HGNCID: 5989
• Length: 599
• Species: Homo sapiens
• Sequence 2: NP_523705.2
• Gene: otk
• FlyBaseID: FBgn0004839
• Length: 1033
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 71/358 (20%)
• Similarity: 130/358 (36%)
• Gaps: 82/358 (23%)

Human   110 TLHFLTPGVNNSGSYICRPKM-----IKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGS 169
            ||.|.:...:::|.|.|:.::     |.|...:...::.:..|...|:.:.|..|         .
  Fly   338 TLSFASIIASDAGQYQCQLQLEAHAPINSSPGILEVIEQLKFVPQPTSKNLELDA---------V 393

Human   170 TGSISCPSLSCQSDAQSPAVTWYKNGK------LLSVERSNRIVVDEVYDYHQGTYVCDYTQSDT 228
            ...:.|.:    ....:|.|.|.::|:      .:.|:.:..::...|...|:|.|.|..|.
  Fly   394 VAKVHCKA----QGTPTPQVQWVRDGENTTLPDHVEVDANGTLIFRNVNSEHRGNYTCLATN--- 451

Human   229 VSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKD 293
             |...:.|.|.:..:| ..|.....:.|:|.:   |.| .:.:.|:| .|..:   |.|:|   |
  Fly   452 -SQGQINATVAINVVV-TPKFSVPPVGPIETS---EQG-TVVMHCQA-IGDPK---PTIQW---D 503

Human   294 SDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQL------ 352
            .||::   :.|..:.:...:  .:|...:..:..|.:....:.|.:.||.|...:.|||
  Fly   504 KDLKY---LSENNTDRERFR--FLENGTLEIRNVQVEDEGSYGCTIGNSAGLKREDVQLVVKTTG 563

Human   353 -----KEKRG----VVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSK--------DQ 400
                 :|..|    |....::..|:.....||....:|   |..    ||....|        .:
  Fly   564 DGFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLML---WCR----YRRQARKARLNDLSTKE 621

Human   401 TLGDKKDFDAFVSYAKWSSFPSEATSSLSEEH 432
            ..||:.|       ...:...||....||::|
  Fly   622 AGGDQPD-------VAGNGKGSEQEPCLSKQH 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IL18RAP	NP_003844.1	Ig	160..>221	CDD:325142	10/67 (15%)
		TIR	419..559	CDD:307630	5/15 (33%)
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706
		Ig	268..373	CDD:299845	8/35 (23%)
		Ig	395..460	CDD:143165	14/73 (19%)
		I-set	468..559	CDD:254352	24/107 (22%)
		IGc2	484..549	CDD:197706	16/78 (21%)
		PTK_CCK4	686..1026	CDD:133178
		STYKc	692..1020	CDD:214568

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.625	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910