Protein Alignment CG42514 and MFSD14B

DIOPT Version :10

• Sequence 1: NP_730171.1
• Gene: CG42514 / 8674108
• FlyBaseID: FBgn0260388
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_115947.2
• Gene: MFSD14B / 84641
• HGNCID: 23376
• Length: 506
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 115/557 - (20%)
• Similarity: 221/557 - (39%)
• Gaps: 148/557 - (26%)

  Fly    24 EDNENSAS----GTVREQR--DEAAGRTVLQW-----AWHVVKSTSVEPTMFLYMFAFMITSVVE 77
            |..|.:||    |.:.|:|  .:|||.|.||.     .:|..      ..:||..||:.:.
Human     8 ELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGRPSVYHAA------IVIFLEFFAWGLL---- 62

  Fly    78 QNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAMLTNAWFLQWENISAHVF------------ 130
                                            |..|||    :..|..|.|.|
Human    63 --------------------------------TTPMLT----VLHETFSQHTFLMNGLIQGVKGL 91

  Fly   131 -PIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNIIYSATLPSALTGADV 194
             ..:.|..:|:.||..||| |.|:|.|   |::...:...|::.|     .|.|.:  :::|...
Human    92 LSFLSAPLIGALSDVWGRK-PFLLGTV---FFTCFPIPLMRISPW-----WYFAMI--SVSGVFS 145

  Fly   195 AIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFNQSYADMFTV-NASLL 258
            ..|:..|||::|::...:|:.....:...:.:::....|:|::|     :.||.|...| .|:::
Human   146 VTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYL-----SASYGDSLVVLVATVV 205

  Fly   259 ALA-IIYTLCALKWQTTPRQRSLRELGCCGFWGDFFD-KQHVKDSLAVLVKPRKGHRRSFLIILL 321
            ||. |.:.|.|:......:.|.:.       ||.... ||  .|..|.|.|..|.   |.::::.
Human   206 ALLDICFILVAVPESLPEKMRPVS-------WGAQISWKQ--ADPFASLKKVGKD---STVLLIC 258

  Fly   322 VSMALYTFQRDEGQY--LYMYTLGKFDWDVSAYSNFKTFKSSAY--------VIAMLLAVPLMNK 376
            :::.| ::..:.|||  .::|        :.....|.:.|.:|:        ::|....:.::.:
Human   259 ITVFL-SYLPEAGQYSSFFLY--------LRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMR 314

  Fly   377 ILGWRDTTIIFIGTWAHSIARLFFY-FATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERG 440
            .||.::|.::.:|   ..:.:|.:| |.:...:::|...|.::..|..|.|.|:.|:...:.::|
Human   315 SLGNKNTVLLGLG---FQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQG 376

  Fly   441 KVFALLS----VCDNAVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAV-----FVMILCLH 496
            ....:::    :|:...|.:.|..:...:  .:.|..|..:....:..|.||     |:...|:.
Human   377 VAQGIITGIRGLCNGLGPALYGFIFYMFH--VELTELGPKLNSNNVPLQGAVIPGPPFLFGACIV 439

  Fly   497 IVLGKNSLAVPEVPEKESGLISQTEAVLEAEIEEHKN 533
            ::....:|.:||. .|.||            :::|.|
Human   440 LMSFLVALFIPEY-SKASG------------VQKHSN 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_SLC46	56..495	CDD:340944	92/474 (19%)
MFSD14B	NP_115947.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		5/16 (31%)
		MFS_MFSD14	45..450	CDD:340945	95/492 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	457..481		3/19 (16%)