DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and Slc35a2

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_511039.2	Gene:	Slc35a2 / 22232	MGIID:	1345297	Length:	393	Species:	Mus musculus

Alignment Length:	417	Identity:	98/417 - (23%)
Similarity:	146/417 - (35%)	Gaps:	127/417 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 VVEQNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAMLTNAWFLQWENISAHVFPIILALFLG 139
            :|.||..|..|.|..|..          |.:..|.|.|:           :.|.|...:..|.|
Mouse    43 LVVQNASLILSIRYARTL----------PGDRFFATTAV-----------VMAEVLKGLTCLLL- 85

  Fly   140 SFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNIIYSATLPSALTGADVAIFASCFAYI 204
            .|:.:||....|::     |.:..::|.........|.::||  ||.:.|            .|:
Mouse    86 LFAQKRGNVKHLVL-----FLHEAVLVQYVDTLKLAVPSLIY--TLQNNL------------QYV 131

  Fly   205 SDISSLQQRTIRVT----ILDVIYLSAMPMGVALGSHLFYNVFNQSYADMFTVNASLLAL----A 261
            : ||:|...|.:||    ||.....|.:.:..:| |.|.:              ||||.|    |
Mouse   132 A-ISNLPAATFQVTYQLKILTTALFSVLMLNRSL-SRLQW--------------ASLLLLFTGVA 180

  Fly   262 IIYTLCA-----LKWQTTPRQRSLRELGCC---GFWGDFFDKQHVKDSLAVLVKPRKGH---RRS 315
            |:....|     ......|.......:..|   ||.|.:|:|         ::|...|.   |..
Mouse   181 IVQAQQAGGSGPRPLDQNPGAGLAAVVASCLSSGFAGVYFEK---------ILKGSSGSVWLRNL 236

  Fly   316 FLIILLVSMALYTFQRDEGQ------YLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAMLLAVPLM 374
            .|.:...::.|......||.      :.:.||...  |.|.....|.         .:|:||.:.
Mouse   237 QLGLFGTALGLVGLWWAEGTAVASQGFFFGYTPAV--WGVVLNQAFG---------GLLVAVVVK 290

  Fly   375 ---NKILGWRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPT 436
               |.:.|:..:..|.:.|.| || |||.:   :.|.|:|      ||  .|.:|.|:....:|
Mouse   291 YADNILKGFATSLSIVLSTVA-SI-RLFGF---HLDPLFA------LG--AGLVIGAVYLYSLP- 341

  Fly   437 SERGKVFALLSVCDNAVPFISGVCYSQ 463
              ||.|.|:.|..      .||.|..|
Mouse   342 --RGAVKAIASAS------ASGPCIHQ 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	82/356 (23%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	85/360 (24%)
Slc35a2	NP_511039.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Nuc_sug_transp	31..339	CDD:282054	88/385 (23%)
		nst	114..338	CDD:129885	67/286 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910