DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and slcr-46.1

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001033534.2	Gene:	slcr-46.1 / 180736	WormBaseID:	WBGene00016705	Length:	481	Species:	Caenorhabditis elegans

Alignment Length:	510	Identity:	116/510 - (22%)
Similarity:	211/510 - (41%)	Gaps:	98/510 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AWHVVKSTSVEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKPENEEFRTKAML 114
            :|.:    :|||.||:.........:|..   ..|..::.|.:...  .:::..:.|::..|.|
Worm    13 SWKI----TVEPLMFVLAACNTAVGIVSP---ALKEMKMKRVYPAP--PDIHGKDLEKYYNKKM- 67

  Fly   115 TNAWFLQWENISAHV-FPI--ILALFLGSFSDRRGRKLPLLMGLVGKFFYSTM-IVVNARMTTWP 175
                 :.|:|...:: .||  :..:..|.:||.||||.|:|:|::.....:.| |::....|.||
Worm    68 -----VMWDNYYEYINLPIACVFGIIYGGYSDHRGRKYPMLIGILSVLVSNAMNILMWDENTDWP 127

  Fly   176 VQNIIYSATLPSA-LTG--ADVAIFASCF-AYIS----DISSLQQRTIRVTIL------------ 220
            :     :.|.|:| :||  .|..:..||. |||:    |..:|..|.:.|:|:
Worm   128 L-----AWTYPTAVVTGVLGDFLLTMSCINAYIADEFPDKITLSYRMVVVSIIFSLGSFVASRFV 187

  Fly   221 -DVIYLSAMP--MGVALGSHLFYNVFNQSYADMFTVNASLLAL----------------AII--- 263
             |::..::.|  |.:|.|.:|            .|...|||.|                :|:
Worm   188 KDLVKWTSKPTVMIIAEGGYL------------LTFLVSLLILDQKKPKTKNCLLKEDESIVTVE 240

  Fly   264 ----YTLCALKWQTTPRQRSLRELGCCGFWGDFFDKQHVKDSLAVLVKPRKGHRRSFLIILLVSM 324
                .:|.:|...|...:.|:.|:....|..       :.|:..:.::||.||||.||.:...:.
Worm   241 GSENQSLASLPNSTQENKLSVFEIIKTSFVA-------IYDAAKIFLQPRAGHRRLFLYLCFAAN 298

  Fly   325 ALYTFQRDE-----GQYLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAMLLAVPLMNKILGWRDTT 384
            .|..|...|     |.|:   .|..|.||.|.|:::|:::....::.|.:.:....:|..:|||.
Worm   299 FLDQFVWGEEKGLLGTYV---RLPPFTWDTSTYADYKSWRPIVQIVGMAVGMLFFKRIFHFRDTF 360

  Fly   385 IIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVC 449
            ||.:...:.:...|....|..:.|::|.....||..::.||.....:.||...|.||.:|:.||.
Worm   361 IICLAILSMTGCVLMIGLAQASWLIFASLAPGSLHGLLNPMSYTFIACIVEQDEIGKAYAISSVA 425

  Fly   450 DNAVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAVFVMILCLHIVLGKNSL 504
            .........:....:|..|.:. :.|.|::|..|.......:...:|::..:.::
Worm   426 QKLAGIAQSLVLQNIYIATVDW-YQGFVWLLMAAISFVAVGIYFIVHVMAKRENV 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	95/383 (25%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	100/416 (24%)
slcr-46.1	NP_001033534.2	NAGidase	<5..116	CDD:369423	26/117 (22%)
slcr-46.1	NP_001033534.2	MFS	72..471	CDD:391944	102/426 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H62662
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		otm14635
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5729
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.950