DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and AgaP_AGAP005319

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_315333.4	Gene:	AgaP_AGAP005319 / 1276033	VectorBaseID:	AGAP005319	Length:	532	Species:	Anopheles gambiae

Alignment Length:	476	Identity:	108/476 - (22%)
Similarity:	202/476 - (42%)	Gaps:	68/476 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 STSV-------EPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNLNKPEN-------- 105
            ||||       ||.:.|..|...::.||..:..:|:||.|...:...:|..|....|
Mosquito    65 STSVTDRLCTFEPILVLLCFGLSVSGVVLADQIIYQSCVVTLGYDRALCAQLGTRSNSSDVAQLE 129

  Fly   106 ---EEFRTKAMLTNAWFLQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVV 167
               :.:..|..:.|       .|...|.|.:.|||:|.:||:.|||..:::..||  |.:|.:::
Mosquito   130 TIVQPYAAKITMVN-------TILMSVLPALCALFMGPWSDKYGRKPAMIVPAVG--FITTYVMI 185

  Fly   168 ------NARMTTWPVQNIIYSATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLS 226
                  :.|....|...::  |.:|:|:.|....:.|:.|:|::|.:|...||:|:.||....:.
Mosquito   186 GILSLLSKRFLVDPWCYVV--AHIPAAILGGSTVLMAAIFSYLTDTTSEANRTVRIGILQACTML 248

  Fly   227 AMPMGVALGSHL--FYNVFNQSYADMFTVNASLLALAIIYTLC---ALKWQTTPRQRSLRELGCC 286
            ...:|:...|.:  :.||....:....||:||   .|.:| .|   ::|...:...|.:||:
Mosquito   249 GAFVGLLSSSFILQWTNVPTMFFLSAGTVSAS---CAFLY-FCLEDSIKPDASMVHRQVREI--- 306

  Fly   287 GFWGDFFDKQHVKDSLAVLVKPRKGHRRSFLIILLVSMALYT-FQRDEGQYLYMYTLGKFDWDVS 350
                  |...|:.:.|....|.|..:.|. ::.|.:|:.:.| .....|...::||..:|.|.:.
Mosquito   307 ------FRLSHLAELLTTFFKKRSFYDRG-IVWLTISIGIVTVLGAGGGTVFFLYTRRQFGWTIQ 364

  Fly   351 AYSNFKTFKSSAYVIAMLLAVPLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVV 415
            .::.::..:..:.|...::.:.::..:|...|..:..:....:::..|....|.....|:....:
Mosquito   365 EFTIWQAVELLSIVAGNVIGISVLKTLLKLPDIWLALLSVLNYALDALIKGLARQGWELFLATGI 429

  Fly   416 CSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCDNAVPFISGVCYSQLYRRTQNTNHGGNVFIL 480
            ..|....|..:.|:.|.|:|:||..|.:::.....|.|...|...::.:|..|..|
Mosquito   430 TPLKATEGAALMAICSAIIPSSEIAKFYSIAMAMTNTVSLASAPLFTYIYNSTVAT--------- 485

  Fly   481 TIATQIAVFVM--ILCLHIVL 499
              :.|:..||.  |..|::||
Mosquito   486 --SPQVFNFVSSGIFSLNVVL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	77/340 (23%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	83/376 (22%)
AgaP_AGAP005319	XP_315333.4	MFS_1	146..465	CDD:284993	75/336 (22%)
AgaP_AGAP005319	XP_315333.4	MFS	146..>288	CDD:119392	41/149 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X552
TreeFam	0	0.000	Not matched by this tool.
	6	5.830