DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42514 and AgaP_AGAP005317

DIOPT Version :9

Sequence 1:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_315331.4	Gene:	AgaP_AGAP005317 / 1276027	VectorBaseID:	AGAP005317	Length:	486	Species:	Anopheles gambiae

Alignment Length:	451	Identity:	105/451 - (23%)
Similarity:	204/451 - (45%)	Gaps:	29/451 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VEPTMFLYMFAFMITSVVEQNFFLYKSCRVNRNFTEEICRNL-NKPENEEFR--TKAMLT-NAWF 119
            :||.:.|..||:.::|.|..|..:|::|.......:.:|..| .:.|.||.:  .||:.. :|..
Mosquito    35 LEPAVLLIFFAWNVSSAVFANQIVYQTCTGAFGKNKSLCDQLGTENETEEIQQLEKAIQPYSANI 99

  Fly   120 LQWENISAHVFPIILALFLGSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNIIY--S 182
            |..:::...:.|.:.::|:|.:|||.|||..::....|.|....::.:.:.::.:...|..|  .
Mosquito   100 LMAKSLVESIIPALGSMFIGPWSDRYGRKPVIVSCFTGAFLTYAIVALISLLSMYYTINPWYYVL 164

  Fly   183 ATLPSALTGADVAIFASCFAYISDISSLQQRTIRVTILDVIYLSAMPMGVALGSHLFYNVFNQSY 247
            |::.:||:|...|:....|.||:|::..:.|..::.|::....:.:..|....|::....   :.
Mosquito   165 ASITTALSGGTCALITGVFCYIADVTVEKTRATKMAIVEAAVFTGLLAGTLSSSYILRWT---NG 226

  Fly   248 ADMFTVNASLLALAIIYTLCALKWQTTPRQRS-----LRELGCCGFWGDFFDKQHVKDSLAVLVK 307
            ..:|.:.|..:.|.::|.:..::....|.:.|     .|||         |....|.:.:....|
Mosquito   227 TTVFAIAAGAVFLGLMYIIFYIEESIKPNELSETNNRAREL---------FRLDLVSELMQTCFK 282

  Fly   308 PRKGHRRSFLIILLVSMALYTFQRDEGQYLYMYTL-GKFDWDVSAYSNFKTFKSSAYVIAMLLAV 371
            .|..:.|..:.::::::|...|..|..|.:::..| .:|:|.|..||.:........:|.....:
Mosquito   283 RRPNYDRLIIWLVILALAANIFAMDGSQTVFLLFLRERFEWTVKDYSYYDASAIVFMIIGNTAGL 347

  Fly   372 PLMNKILGWRDTTIIFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPT 436
            .::.|:.....|.:..:|...::|.......|:....||.|..:|.:..|.|||.||:.|...|.
Mosquito   348 YVIRKLFNPSVTVLAALGYCCYAINSTIQALASEPWHLYMGTAICFMKGIAGPMSRAVISNTAPP 412

  Fly   437 SERGKVFALLSVCDNAVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAVFVMILCLHI 497
            ::.||:|:|.:..::..|..|...|:.:|:.|.....|  .|.|..||   |:....||.|
Mosquito   413 NDIGKIFSLTTSIESITPLFSAPLYTFVYKSTLAWYPG--AFNLITAT---VYFTCACLMI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	73/336 (22%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	82/370 (22%)
AgaP_AGAP005317	XP_315331.4	MFS	108..469	CDD:119392	86/378 (23%)
AgaP_AGAP005317	XP_315331.4	MFS_1	108..434	CDD:284993	73/337 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X552
TreeFam	0	0.000	Not matched by this tool.
	6	5.830