DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42594 and Kcnk16

DIOPT Version :9

Sequence 1:	NP_001162668.2	Gene:	CG42594 / 8674091	FlyBaseID:	FBgn0260971	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	NP_083282.1	Gene:	Kcnk16 / 74571	MGIID:	1921821	Length:	292	Species:	Mus musculus

Alignment Length:	276	Identity:	60/276 - (21%)
Similarity:	98/276 - (35%)	Gaps:	102/276 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   587 VGGVAVGGGP--PHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAFFGIPLTLVYLSS 649
            |.||...|..  |..|:|..:|.::.||:|||||||:||.|..|::..:.||..||||.:|:|:.
Mouse    78 VKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNH 142

  Fly   650 TGSILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQEELRKQQAVMQEPYYVR 714
            .|:.|                                :.......|.::..|..|.
Mouse   143 LGTGL--------------------------------RAHLTTLDRWEDHPRHSQL--------- 166

  Fly   715 DVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLSILAPILLCFSMMIIYI 779
                                                           |.:|...|......::.:
Mouse   167 -----------------------------------------------LQVLGLALFLTLGTLVIL 184

  Fly   780 VFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLPGLRRESNATTWFCSVY-------IMSGMT 837
            :|.......:|.|...:|.||.|::||||||||.:.|    ::.:..:.:||       |:.|:.
Mouse   185 IFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVG----TDPSKHYIAVYRSLAAIWILLGLA 245

  Fly   838 LTAMCFNVIHEEIVHR 853
            ..|:..: :...::||
Mouse   246 WLAVVLS-LGSLLLHR 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	26/56 (46%)
		Ion_trans	<601..640	CDD:278921	17/38 (45%)
		Ion_trans_2	774..846	CDD:285168	21/78 (27%)
Kcnk16	NP_083282.1	Ion_trans_2	<92..148	CDD:285168	26/87 (30%)
Kcnk16	NP_083282.1	Ion_trans_2	180..248	CDD:285168	20/71 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010