DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42594 and Kcnk12

DIOPT Version :9

Sequence 1:NP_001162668.2 Gene:CG42594 / 8674091 FlyBaseID:FBgn0260971 Length:1039 Species:Drosophila melanogaster
Sequence 2:NP_954859.1 Gene:Kcnk12 / 210741 MGIID:2684043 Length:430 Species:Mus musculus


Alignment Length:353 Identity:89/353 - (25%)
Similarity:130/353 - (36%) Gaps:115/353 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   523 LNED----------VMLQLSHDDVANAPSSSSSSSSSSSSSSSSTGA-----SGVPGSNNPATEA 572
            ||||          :.|.|    ||.|...|:..|...:.:.:..||     |...|...|...|
Mouse    32 LNEDTGRFVLLAALIGLYL----VAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPELRA 92

  Fly   573 VLLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRIVTLAYAF 637
            .|     .|:.|....||......| .|:|..||.:..||::|||:|...|.|..|:...:||..
Mouse    93 FL-----RHYEAALAAGVRADALRP-RWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGL 151

  Fly   638 FGIPLTL----VYLSSTGSILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKRQQE 698
            ||...|:    ::|....|:||.:.|                         |.:||::||.    
Mouse   152 FGCAGTILFFNLFLERIISLLAFIMR-------------------------ACRERQLRRS---- 187

  Fly   699 ELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMHGLS 763
                            .:..||..:               ||  .|.:.||| |.......|   
Mouse   188 ----------------GLLPATFRR---------------GS--ALSEADSL-AGWKPSVYH--- 215

  Fly   764 ILAPILLCFSMMIIYIVFGAAVLY-RLEKWPILDGIYFCFMSLSTIGFGDML---------PGLR 818
                :||...:..:.:...|:.:| .:|.|..:|.:||||::.|||||||::         .||.
Mouse   216 ----VLLILGLFAVLLACCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLY 276

  Fly   819 RESNATTWFCSVYIMSGMTLTAMCFNVI 846
            |..|      .::|:.|:......||||
Mouse   277 RLGN------FLFILLGVCCIYSLFNVI 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42594NP_001162668.2 Ion_trans_2 <599..656 CDD:285168 21/60 (35%)
Ion_trans <601..640 CDD:278921 15/38 (39%)
Ion_trans_2 774..846 CDD:285168 24/81 (30%)
Kcnk12NP_954859.1 Ion_trans_2 101..169 CDD:400301 22/68 (32%)
Ion_trans_2 222..304 CDD:400301 26/83 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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