DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42594 and AgaP_AGAP013077

DIOPT Version :9

Sequence 1:	NP_001162668.2	Gene:	CG42594 / 8674091	FlyBaseID:	FBgn0260971	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	XP_003436359.1	Gene:	AgaP_AGAP013077 / 11176095	VectorBaseID:	AGAP013077	Length:	262	Species:	Anopheles gambiae

Alignment Length:	311	Identity:	105/311 - (33%)
Similarity:	133/311 - (42%)	Gaps:	127/311 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 KSRKAT------SQTVWSALLTNLGICMLLLAYTLLGSFIFLTIENEDSALLHQQHTLASTKRNL 371
            |:|..|      |.|.|:|||||:|:|.||||||||||||||.||...|.:  ||.|||||.|:
Mosquito    68 KARCCTCCAGRGSSTFWAALLTNIGVCTLLLAYTLLGSFIFLAIEGGASQM--QQRTLASTNRH- 129

  Fly   372 AGLGIGAAGIGSSIYQQQQQQQQQRTPHQQQQQHQAVQGRHADNDTMAAAAAAVAAQGTLAGSAS 436
                                  |::.|......:....|||
Mosquito   130 ----------------------QKQLPVNNNNNNNNHHGRH------------------------ 148

  Fly   437 AGGLNPFGQPASSGEFVYGLDGMDATDLEAGGMPQFALSPDTYDVRQRTIENIWDITVSLNILYK 501
                                   |..:|.   .||..|. :..:.||:|:||||||||||||||:
Mosquito   149 -----------------------DTANLT---FPQLILL-EAVEARQKTVENIWDITVSLNILYR 186

  Fly   502 ENWTKLAALEIAKFQDQLIKRLNEDVMLQLSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGSN 566
            ||||:||::|||:||:|.:.||.|: |.|:::...|.||
Mosquito   187 ENWTRLASMEIARFQEQFVNRLLEE-MTQINNMQHAGAP-------------------------- 224

  Fly   567 NPATEAVLLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIG 617
                              |..|....|.||.:.|.||:|||||||:|||||
Mosquito   225 ------------------GTAGHELAGHGPDNNWTFARAFLYSLTILTTIG 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	15/19 (79%)
		Ion_trans	<601..640	CDD:278921	14/17 (82%)
		Ion_trans_2	774..846	CDD:285168
AgaP_AGAP013077	XP_003436359.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0014284
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13494
TreeFam	0	0.000	Not matched by this tool.
	3	2.910