DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42594 and kcnk17

DIOPT Version :9

Sequence 1:	NP_001162668.2	Gene:	CG42594 / 8674091	FlyBaseID:	FBgn0260971	Length:	1039	Species:	Drosophila melanogaster
Sequence 2:	XP_005158968.1	Gene:	kcnk17 / 101882139	ZFINID:	ZDB-GENE-120113-3	Length:	299	Species:	Danio rerio

Alignment Length:	347	Identity:	76/347 - (21%)
Similarity:	122/347 - (35%)	Gaps:	133/347 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   502 ENWTKLAALEIAKFQDQLIKRLNEDVML-QLSHDDVANAPSSSSSSSSSSSSSSSSTGASGVPGS 565
            |.|..|.  :||..:::.::.|.:...| |....::|....|:|.|..|..|:.::.|.
Zfish    43 EGWYVLQ--QIALLKEKRLELLEKYPCLGQNGLSELAQMIKSASLSGLSPDSNDTADGL------ 99

  Fly   566 NNPATEAVLLHTHYHHHRAGGVGGVAVGGGPPHEWNFAKAFLYSLTVLTTIGYGNVAPRTTLGRI 630
                                              |.|..:.:::.||:|||||||:.|.||.|:|
Zfish   100 ----------------------------------WKFTSSSVFAATVVTTIGYGNIVPLTTAGQI 130

  Fly   631 VTLAYAFFGIPLTLVYLSSTGSILARVAREVFSKALCCCLCSNCGYCCYDEKRMAEKERRMRRKR 695
            ..:.:|.|||||.:|.|:..|..:..:.|.               :|.:.||::
Zfish   131 FCVMFALFGIPLNVVVLNRVGKYMLAIERH---------------FCNFLEKKI----------- 169

  Fly   696 QQEELRKQQAVMQEPYYVRDVFHATPEKDAGAGAPPPNAGGPVGSVGGLGDIDSLSASESRGSMH 760
                                        |.|...                          |.|:|
Zfish   170 ----------------------------DRGKCV--------------------------RISIH 180

  Fly   761 GLSILAPILLCFSMMIIYIVFGAAVLYRLEKWPILDGIYFCFMSLSTIGFGDMLPGLRRESNATT 825
            .:|.:       |...:|:|....:....|.|...:.||:||::||||||||.:.....|.|...
Zfish   181 SISFV-------SSAFLYLVVPMLLFKEYEGWSYAEAIYYCFITLSTIGFGDYVADHNPEINYPE 238

  Fly   826 WF-C--SVYIMSGMTLTAMCFN 844
            |: |  :|:|..|:...|:..|
Zfish   239 WYSCLMAVWIFFGLAWLALLVN 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42594	NP_001162668.2	Ion_trans_2	<599..656	CDD:285168	25/56 (45%)
		Ion_trans	<601..640	CDD:278921	17/38 (45%)
		Ion_trans_2	774..846	CDD:285168	25/74 (34%)
kcnk17	XP_005158968.1	Ion_trans_2	<100..154	CDD:285168	25/53 (47%)
kcnk17	XP_005158968.1	Ion_trans_2	189..267	CDD:285168	25/72 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010