DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42556 and Y76A2B.5

DIOPT Version :9

Sequence 1:	NP_001162994.1	Gene:	CG42556 / 8674031	FlyBaseID:	FBgn0260758	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_499801.1	Gene:	Y76A2B.5 / 176786	WormBaseID:	WBGene00013577	Length:	283	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	53/229 - (23%)
Similarity:	83/229 - (36%)	Gaps:	61/229 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PNCVGPAYQGLISSLDQPYT---------TDCYMAD-EQTLVK-------ENDSIH-----DTIL 112
            ||.....:||.:|...:|.:         .:..|.| |..|:.       |.|..|     :..:
Worm    47 PNDSQYPFQGDVSFAHKPLSIRQQVENSKIERVMDDTEHNLINLLSNTNIEVDRTHLAQLKEEAM 111

  Fly   113 ESLVA-----PTEMCVVACPKLLLTYMRRLFQHPYARFGSSMNFSMIGLRFK------------D 160
            |.:.|     ..|:..:..||||...|:.||  |........|.::..|..|            :
Worm   112 EEIQANAADVEIELSAIEAPKLLKKEMKYLF--PQMETQKMNNVTVFNLTQKSEFDMKAWSEAME 174

  Fly   161 KDANKALTSFVHFASYNSREIMDNGYWADFINPLTGRAY---------YRAAHCIRKQGLEAQLL 216
            ::..|...||:..|:.....:...|||||||:|.:||.|         :......::.|.:.:.|
Worm   175 EEREKLTASFIMSANAICSTLHRFGYWADFIDPSSGRPYMGDYTNHTLFETNDAYKQMGFKIEDL 239

  Fly   217 GRGLNLTFANGCTIIGEE--QSDQLTGFIFTDTP 248
            |         .|.::...  .|:...|.||||.|
Worm   240 G---------CCKVLQHACWGSNAFVGTIFTDAP 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42556	NP_001162994.1	DUF2246	<117..248	CDD:287231	38/158 (24%)
Y76A2B.5	NP_499801.1	DUF2246	5..274	CDD:287231	53/229 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1363001at2759
OrthoFinder	1	1.000	-	-		FOG0006544
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105788
Panther	1	1.100	-	-	LDO	PTHR13192
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920