Protein Alignment Nost and nostrin

DIOPT Version :10

• Sequence 1: NP_001285029.1
• Gene: Nost / 8673992
• FlyBaseID: FBgn0259734
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: XP_012826762.2
• Gene: nostrin / 100489418
• XenbaseID: XB-GENE-988808
• Length: 538
• Species: Xenopus tropicalis
• Alignment Length: 674
• Identity: 150/674 - (22%)
• Similarity: 269/674 - (39%)
• Gaps: 172/674 - (25%)

  Fly   669 FEELRRYVKQGGDFSKELIFVLQERADSELIYSKSLSKLANKLNKAGREI-PGSVADAWRGVATE 732
            :::|:...|.|..|.|.|:..||:|::.||.|:|.|.|:||||.||...: ...:.:||...:.|
 Frog    14 YKDLKNISKNGEIFCKTLMSALQQRSNLELSYAKGLEKVANKLTKALASVNKNCINNAWTCASDE 78

  Fly   733 MESRSDIHRQLAASLTDELVKPLKIVVEGHHKARKAVESNVDK-AARVLGEWRAS-EAKAKKASH 795
            |.:.:::|::|..::..|.:||...|:|.|.|.:|.:::.|:| .:.||..|:.. :.|.|...|
 Frog    79 MRTTAEVHKKLGTAIQQEAIKPTSQVLEEHEKKKKKLDNEVEKMTSSVLNNWKQQIKVKKKLMEH 143

  Fly   796 TAARENEKLQDAMLDVRIQKSPSIALLH--QGPNKQAAEKELKSAEKDCVKLDNKRKKAEEAVKR 858
            |...|                   ||.|  ...|||:.      .||:..||.||.||:.:.:.:
 Frog   144 TKKHE-------------------ALFHHVDNTNKQSL------TEKEKQKLLNKLKKSVDTLTK 183

  Fly   859 ADVEYYTLCVRSERARVDWEMAVLRGSAQLQSSEQQRLGNMHNFAQQYARLISDMNPILGGLSTR 923
            .|.:||...:..:..|:.||..:......:|..|::|:..:.:...:|.:.:......|....::
 Frog   184 TDEDYYQDNISGQTVRLKWENVLENCYKSIQDLEKERIQLLSHILNRYNQHVLTFGQTLNTCQSQ 248

  Fly   924 LQPQLDACNVAKDMQVVRHIRR--NSEGPSEQLLPDFYCEHTTLAMNRERRKHALIKLLQLVKTD 986
            :...:.:.:|.||:|.......  :.|..||.||.|::.|.:::.|::|||..::...|:.::.|
 Frog   249 IDQAIKSIDVEKDIQTFMEETAIYSEENKSEFLLMDYFEEDSSVIMDKERRIASINMKLERLQGD 313

  Fly   987 LERERRSRDGLRGLSQSL-------NHQEHQNITDKLYHIRSMLTYLEGARLKLHSALLELDHKP 1044
            :::.::.:|||..:.::.       :.:..:|....|......:..||....||.|.|.||:.:.
 Frog   314 IDKAQKDKDGLEKMLKAYVDNPAFSDVKNEENTIILLEETNLKIHLLEANHFKLLSTLAELEGRS 378

  Fly  1045 RATHPLAQHIHITRDRTGLQQSILKVPNWLKNNDKSQTQQSTSMLAHDITDITTNHEDELPDENC 1109
            .:.||.::                ::..|.:...:
 Frog   379 LSPHPCSE----------------RISKWKEKGSQ------------------------------ 397

  Fly  1110 SHLHSSSHSNNNSNGSCTDVSSVVKPFNRSKSNIETNFTSQPKIISTTNAAIAVSVKSKTLANLQ 1174
               |||.:                                           |:.::.::.|..|:
 Frog   398 ---HSSVY-------------------------------------------ISRAINTRKLKRLE 416

  Fly  1175 DGHHNNQQHHHHHHNHHSDRGQADGGSNQQDSDFDEFSSQDEDDEPQQPQQQPQPLQSQQQQQQP 1239
            ....:|:......|:                ..||:....|..|.|.:|   |:.|   .::.:.
 Frog   417 SQRISNRSRDRMSHS----------------VSFDDSKESDTTDYPNKP---PRGL---SRRVKD 459

  Fly  1240 LLQNPTINGQVQTQHFYQNAQELQKGQKNGSVPILGRCKALYSYTPKLYDELELSPGDIIEVHAK 1304
            |.:..|.|.:........                   |..||.|.|:..|||.|..||::|:|.|
 Frog   460 LHEENTPNNETNEHRRIS-------------------CTVLYPYKPQRQDELGLQKGDLLEIHHK 505

  Fly  1305 QDDGWWLGALRNHIGIFPATYVEE 1328
            .|||||.|:|....|.||:|||:|
 Frog   506 DDDGWWYGSLNGKKGYFPSTYVQE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nost	NP_001285029.1	F-BAR_NOSTRIN	663..908	CDD:153342	69/243 (28%)
		SH3_Nostrin	1276..1328	CDD:212757	27/51 (53%)
nostrin	XP_012826762.2	BAR	9..251	CDD:472257	70/261 (27%)
		HR1	297..375	CDD:469609	17/77 (22%)
		SH3_Nostrin	477..529	CDD:212757	27/70 (39%)