Protein Alignment SLC22A16 and CG7342

DIOPT Version :9

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 620
• Identity: 138/620 - (22%)
• Similarity: 246/620 - (39%)
• Gaps: 151/620 - (24%)

Human     9 IYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRP--PGNVSQVVFHNHSNWSL 71
            |.:..|.|.|.|.::..:....|:...:||.:...:...|.:.|..  |.::...|
  Fly     7 ILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPASIESPV--------- 62

Human    72 EDTGAL-LSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNT 135
             |:..| |:.......|....|.|::               :||:...|:.::.|.|       .
  Fly    63 -DSSCLPLNRNISTPNTCYSYNYELY---------------MGYQSFPSEMDWVCAD-------A 104

Human   136 WKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVL--------------- 185
            ||.|                |.|.:|..|.::||:..||.:|.:||..:|
  Fly   105 WKLT----------------LGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTI 153

Human   186 WATSSSMF-LFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWA-SVHLHS 248
            |:|:.::| :|.:.:..|.|               |.:::: ::.|||::....||.. |:.:..
  Fly   154 WSTNVTLFCMFRMISGIATD---------------SNFVMM-YILVMEYMRPSVRTLGLSICIGF 202

Human   249 FFAVGTLLVALTGYLVRTW--WLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIM 311
            |:.:|::.......|:|:|  :|....|..:.|||...  ::||:..||:|:.:|:.|...:..:
  Fly   203 FYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYL--IVPESIQWLISKQKYDSAVVCLKRV 265

Human   312 AKWNR-----------ASSCKLSE--------LLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITK 357
            ||.|.           ...||.|:        ||.| .|.|      .:::|.|...|.:..||
  Fly   266 AKINGRHVEESAYAEFIEECKCSQQNQKASPHLLDL-FQTP------RLRRHTLILFFKSMVIT- 322

Human   358 RTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSL 422
                         |.:.:.|.|...||.:.::...|.....:||...:....|::||:.:.:.||
  Fly   323 -------------LCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASL 374

Human   423 FCSALACGVVMVI------PQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSG 481
            ..|.:...|...|      ..|...|.|..::||:|.:..|:.....|..||.||.||...|.:.
  Fly   375 LLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAV 439

Human   482 SMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATT----------- 535
            .:.....:..:.:.:...|::..:|::.:|.::||...|.|.|||||.:.|.|:
  Fly   440 HVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSLEDGENFGKND 504

Human   536 -WEEAAKLESENESKSSKLLLTTNNSGL--EKTEA 567
             |...:.||...:|.::   |.|.|:.:  :.||:
  Fly   505 RWYTFSFLEGRTQSAAT---LDTQNAKMYSQSTES 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	127/567 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577		7/27 (26%)
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	126/565 (22%)
		MFS	93..>243	CDD:119392	41/190 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850