Protein Alignment SLC22A16 and CG6006

DIOPT Version :8

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Alignment Length: 558
• Identity: 152/559 (27%)
• Similarity: 263/559 (47%)
• Gaps: 63/559 (11%)

Human     9 IYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLED 73
            |.|.:||:|::|.::..:.:...:....|..:|::........|:.|..:..:......|
  Fly    85 IGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHMPVATWRN----- 144

Human    74 TGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTG--SKKEFPCVDGYIYDQ--- 133
                 .||..|       |...||....|:...|.|....::...  .||...| :.:.|:.
  Fly   145 -----LSGSVD-------NCRRWEGIDWSQVSNETTLPSDWKTPAEMDKKLVAC-EKWEYETNDN 196

Human   134 --NTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFG 196
              |||.|    ||:|||:::.|..:.:..|:.||..|.:..||.||:.||:.:|:.::....:||
  Fly   197 VGNTWTS----QWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFG 257

Human   197 IAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTG 261
            :.......:..::..|..|.:|:......|.:..:|::..|.||.|.::......:..::::...
  Fly   258 LWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIAGMYNLFPLPISYMIISGLA 322

Human   262 YLVRTWWLYQMILSTVTVPFILCC--W-VLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLS 323
            ||.:.   ||.:...:.:|.|..|  | |:||:|.|||.:||.:|.::|::..||:|       .
  Fly   323 YLTQD---YQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFN-------G 377

Human   324 ELLSLDLQ--GPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGN 386
            ..|..|.|  .|...|.|:    :::|||.:..:.:.::..:.||||.:|.:|...||..:.|||
  Fly   378 RQLPADYQLTPPTQESSTQ----DVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGN 438

Human   387 EYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKH---YILGVVTAM 448
            .|||..|.|:|||||.......:.|||::.:...:|.|:.:|| ....|.:.|   ..|.:...|
  Fly   439 VYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVAC-CCAAITEGHADLLWLKITFLM 502

Human   449 VGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTM 513
            :|||.|.|...::.:||||||||.:|::.||:.::...||.||.|:...|:.|...:....:...
  Fly   503 MGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGHLLMTLLTAW 567

Human   514 ALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSS 551
            ::..|.:.|.||||           |.:.:::|:..||
  Fly   568 SIFGGFVVLFLPET-----------AVRQKTDNQGGSS 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	146/536 (27%)
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	145/528 (27%)
		MFS	222..579	CDD:119392	111/372 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG0255
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D386678at33208
OrthoFinder	1	1.000				FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.010