Protein Alignment SLC22A16 and CG15221

DIOPT Version :8

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 115/500 (23%)
• Similarity: 191/500 (38%)
• Gaps: 124/500 (25%)

Human   148 CDRKWLAMLIQPLF----------MFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFA 202
            ||       :||..          ..||:|.|...|:.:|..||...|........:..|.:||:
  Fly    77 CD-------LQPTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFS 134

Human   203 VDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSF----------FAVGTLLV 257
            |:.:..:..||......||.....|....||.|..||......|..|          .|:|.|.:
  Fly   135 VNIWMLIVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPL 199

Human   258 AL----TGYLVRTWWLYQMILSTVTVPFILCCWV--LPETPFWLLSEGRYEEAQKIVDIMAKWNR 316
            .:    .|....:|.:  ::|:.|::|.:....:  |||||.:||.:||.:|:.:::..:...|.
  Fly   200 RIETIVLGMHFSSWRV--LLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRSIFANNS 262

Human   317 A---SSCKLSELLSLDLQGPVSNS-------PTEVQKHNLSYLFYN---WSITKRTLTVWLI--- 365
            .   |...:.| ::|: .|.||.|       ...:..|....|||.   |    .||.:..|
  Fly   263 GRDPSEYPVKE-VALE-SGGVSLSDVHGFLDAVRLVWHQTVPLFYRARLW----HTLNICCIQFI 321

Human   366 ----------WF---TGSLG------------FYSFSLN----------SVNLGGNEYLNLFLLG 395
                      ||   ...||            ...|::|          ||.:..:.|..:.::.
  Fly   322 IYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVEVDTSTYQVMIIIA 386

Human   396 VVEIPAYTFVCIAMDKVGRRTVL-AYSLFCSALACGVVMVIPQKHYI---LGVVTAMVGKFAIGA 456
            ...:..|......:|.:|::.:| |:.:.  .:.|.|.:     ||:   ..||.|:....|||.
  Fly   387 ACFVVIYLIFAYIIDYMGKKNLLMAWMVL--TMICLVAL-----HYVEQFALVVIALTVVMAIGN 444

Human   457 AFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGT-----MALL 516
            ..||:.....|.|||.:.::.:....||.||.:::.      |:|   :.:|...:     .|||
  Fly   445 CGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVG------SNI---LGRLLFASCDPIFWALL 500

Human   517 SGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNS 560
            :.|:.|.   |||..|    .|.|:.:.:..|.::|.::|...|
  Fly   501 ALVVLLC---TLGYFL----PEKARSQQKKPSATAKAIVTATTS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	109/473 (23%)
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	100/442 (23%)
		MFS	51..488	CDD:119392	100/442 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C62667333
eggNOG	1	0.900				E1_KOG0255
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.830