DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC22A16 and CG33233

DIOPT Version :9

Sequence 1:NP_149116.2 Gene:SLC22A16 / 85413 HGNCID:20302 Length:577 Species:Homo sapiens
Sequence 2:NP_995978.2 Gene:CG33233 / 2769005 FlyBaseID:FBgn0053233 Length:489 Species:Drosophila melanogaster


Alignment Length:431 Identity:89/431 - (20%)
Similarity:154/431 - (35%) Gaps:129/431 - (29%)


- Green bases have known domain annotations that are detailed below.


Human   164 GVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARF----FLAMVASGYLV 224
            |::...:..|:.:||.||:.|:.........|.:.:|...|.|:....|.    ||:.|||  |.
  Fly    68 GMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVAS--LQ 130

Human   225 VGFVYVMEFIGMKSRTWASVHL------HSFFAVGTLLVAL------------TGYLVRTWWLYQ 271
            |||  :.||..:|   |..:.:      .....:...|||:            :.|.:|.|....
  Fly   131 VGF--LGEFHAIK---WRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLM 190

Human   272 MILSTVTVPFILCCW-------VLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLD 329
            |.       |::..|       ::||||.:|:|..|.::|...:..:.:.||      .:...:|
  Fly   191 MF-------FMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNR------KKWEDVD 242

Human   330 LQGPVSNSPTEVQK-------HNLSYLFYNWSITKRTLTVWLIW--FTGSLG---FYSFSLNSVN 382
            :......|.|..|:       :....||....:.|..:.::||:  |..|:|   ::....|..|
  Fly   243 ITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVIRNMDN 307

Human   383 LGGNEYLNLF---------------------------LLGVVEIPAYTFVCIAMDKVGRRTVLAY 420
            .|.|...:|.                           :..:::...|.|..|.            
  Fly   308 SGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIG------------ 360

Human   421 SLFCSALACGVVMVIPQKHYI-LGVVTAMVGKFAIGAAFG--------LIYLYTAELYPTIVRSL 476
               |..||..:|..:.:|:.| |.::.:|:    :|.:..        ||:.....:.|.::..|
  Fly   361 ---CFILASVLVHWMTRKYVIALHILISMI----LGISLNIMKQPTVVLIFFVLMMVLPGVLIPL 418

Human   477 AVG----------SGSMVCRLASILAPFSVDLSS--IWIFI 505
            |..          .|..:|.:.| ||.|...|.|  |.:||
  Fly   419 ATSVLVDCLPVNLRGKALCMVRS-LARFGGVLGSTMIGLFI 458

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC22A16NP_149116.2 Sugar_tr 14..535 CDD:331684 89/431 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 543..577
CG33233NP_995978.2 MFS_1 22..451 CDD:284993 85/422 (20%)
MFS 23..>208 CDD:119392 34/153 (22%)
MFS 354..>482 CDD:304372 28/125 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165153321
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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