Protein Alignment SLC22A16 and CG33233

DIOPT Version :8

• Sequence 1: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 431
• Identity: 89/432 (21%)
• Similarity: 154/432 (36%)
• Gaps: 129/432 (30%)

Human   164 GVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARF----FLAMVASGYLV 224
            |::...:..|:.:||.||:.|:.........|.:.:|...|.|:....|.    ||:.|||  |.
  Fly    68 GMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVAS--LQ 130

Human   225 VGFVYVMEFIGMKSRTWASVHL------HSFFAVGTLLVAL------------TGYLVRTWWLYQ 271
            |||  :.||..:|   |..:.:      .....:...|||:            :.|.:|.|....
  Fly   131 VGF--LGEFHAIK---WRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLM 190

Human   272 MILSTVTVPFILCCW-------VLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLD 329
            |.       |::..|       ::||||.:|:|..|.::|...:..:.:.||      .:...:|
  Fly   191 MF-------FMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNR------KKWEDVD 242

Human   330 LQGPVSNSPTEVQK-------HNLSYLFYNWSITKRTLTVWLIW--FTGSLG---FYSFSLNSVN 382
            :......|.|..|:       :....||....:.|..:.::||:  |..|:|   ::....|..|
  Fly   243 ITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVIRNMDN 307

Human   383 LGGNEYLNLF---------------------------LLGVVEIPAYTFVCIAMDKVGRRTVLAY 420
            .|.|...:|.                           :..:::...|.|..|.
  Fly   308 SGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIG------------ 360

Human   421 SLFCSALACGVVMVIPQKHYI-LGVVTAMVGKFAIGAAFG--------LIYLYTAELYPTIVRSL 476
               |..||..:|..:.:|:.| |.::.:|:    :|.:..        ||:.....:.|.::..|
  Fly   361 ---CFILASVLVHWMTRKYVIALHILISMI----LGISLNIMKQPTVVLIFFVLMMVLPGVLIPL 418

Human   477 AVG----------SGSMVCRLASILAPFSVDLSS--IWIFI 505
            |..          .|..:|.:.| ||.|...|.|  |.:||
  Fly   419 ATSVLVDCLPVNLRGKALCMVRS-LARFGGVLGSTMIGLFI 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	89/432 (21%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	85/423 (20%)
		MFS	23..>208	CDD:119392	34/154 (22%)
		MFS	354..>482	CDD:304372	28/126 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C62666221
eggNOG	1	0.900				E1_KOG0255
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.830