Protein Alignment SLC38A1 and CG16700

DIOPT Version :8

• Sequence 1: NP_001265319.1
• Gene: SLC38A1 / 81539
• HGNCID: 13447
• Length: 503
• Species: Homo sapiens
• Sequence 2: NP_573191.1
• Gene: CG16700 / 32694
• FlyBaseID: FBgn0030816
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 114/509 (22%)
• Similarity: 200/509 (39%)
• Gaps: 107/509 (21%)

Human     9 ELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSL 73
            :|.:.|..|||..:.....|...|.|  |...:|...:::...             ||.|.|:.|
  Fly     8 QLEKNQTATVPRQETAEGGSTGETAV--GGAAAKVTKEQDHDA-------------EYHPPTSYL 57

Human    74 GMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSK-------ETGC 131
             .::.:|....:|.|:..:..|..|.|:|:..:|...:.::||:..::|:.|||       ::.|
  Fly    58 -ETIVHLFKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVC 121

Human   132 MVYEKLGEQVF-----------GTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEE 185
            ..|.:..||.|           .|.|:.|.......|.....:.::||..|           .::
  Fly   122 ADYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTN-----------LKQ 175

Human   186 TFSAWYVDGRV-LVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPE 249
            ...|:.:|..| ||:::.|..:|...|:.||.:|...|.|:..||:..|.:.:|  :.:...:||
  Fly   176 ILQAYDIDMNVHLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLY--YALKDGLPE 238

Human   250 LNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQM-VSNI 313
            :..  .|..||           .|:......|..|||.....|:|:.:.::...|.:..: |.|:
  Fly   239 VEE--RALWTN-----------GSQLALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNV 290

Human   314 SFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTV--- 375
            ..|.:.||:......||:.:.:.|...|  .....|.||...|:|.|...|:|..|:.||..
  Fly   291 GMFLVSVMFMFAGSVGYMKWGEQVGGSL--TLNLGDTILAQAVKLMVSAGVLLGYPLQFFVAIQI 353

Human   376 -------------RSSLFELAKKTKFNLCRHTVVTCILLVVINLLVI-FIPSMKDIFGVVGVTSA 426
                         ||.|.||..:|             .:|::.|.:. .:|::.....::|...:
  Fly   354 MWPNAKQMCGIEGRSLLGELGFRT-------------FMVLVTLAIAEMVPALGLFISLIGALCS 405

Human   427 NMLIFILPSSLYLKITDQDGDKGTQRIWLFLFLQFPVQPCWLSECIILLPAAL 479
            ..|..:.|..:.| |:..:.:|| ..||:          | :...:||:.|.|
  Fly   406 TALALVFPPVIEL-ISRSELNKG-PGIWI----------C-VKNLVILVLALL 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC38A1	NP_001265319.1	SdaC	68..441	CDD:223884	92/410 (22%)
		SLC5-6-like_sbd	69..480	CDD:294310	101/449 (22%)
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	101/449 (22%)
		SdaC	57..452	CDD:223884	100/445 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C97453461
eggNOG	1	0.900				E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840