DRSC/TRiP Functional Genomics Resources

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Protein Alignment: PIP4K2C and PIP4K

Sequence 1:NP_001139730.1 Gene:PIP4K2C HGNCID:23786 Length:421 Species:Homo sapiens
Sequence 2:NP_001033805.1 Gene:PIP4K FlyBaseID:FBgn0039924 Length:404 Species:Drosophila melanogaster

Alignment Length:410 Identity:210/411 (51%)
Similarity:274/411 (67%) Gaps:47/411 (11%)


Human    29 KKKHF--VQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHR 91
            |||||  ..||||:|||.:|::.||:||:.|:|||||.|..|||||||||:|.|||||:||||::
  Fly    15 KKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAYSKIKVDNHLFNK 79

Human    92 ENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFLISYDRTLVIKE 153
            ||:|||||.|||||.||||||:|||:||.||..||||:.|  .:|.|..| :|..|||:..:||.
  Fly    80 ENMPSHFKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKS 144

Human   154 VSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
            ::||:|..||:.|..||.|:|:.||.|||||:|||||::|::...|.:||||:||..|.:|:|:|
  Fly   145 LTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFD 209

Human   219 LKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSL 283
            ||||.|.||||:||..|.|||.||.||:.:..|:.||:|.|...::.|..||:.|.:|.||||||
  Fly   210 LKGSTVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSL 274

Human   284 LLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVG----------------SYGTSPEGI 332
            |:|:||.:|.   ||||        :.||..||     ||                :|.|.|:..
  Fly   275 LVGVHDCVRA---EEEA--------LQGDNILT-----VGRSENSESEECDSGERWTYNTPPDSP 323

Human   333 GGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
            .|..:.       |....:|:|.|.|.|  .::|:||:.:||:||||..||:||.||||||:|:.
  Fly   324 RGAQYK-------EVVYEVDIYDIPSIE--EKREIYFIAIIDVLTQYGVKKQAAKAAKTVKYGSN 379

Human   398 AE-ISTVHPEQYAKRFLDFI 416
            .: |||..|||||||||||:
  Fly   380 VDGISTCDPEQYAKRFLDFM 399

Known Domains:


GeneSequenceDomainRegion External IDIdentity
PIP4K2CNP_001139730.1 PIPKc 72..420 CDD:214623 182/366 (50%)
PIP4KNP_001033805.1 PIPKc 32..403 CDD:295374 198/394 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG5253
Hieranoid 1 1.000
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 455 1.000 Inparanoid score I1569
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D1562683at2759
OrthoFinder 1 1.000 FOG0000924
OrthoInspector 1 1.000 T609413
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 O PTHR23086
Phylome 1 0.910 0.857 Consistency score
RoundUp 00.000 Not matched by this tool.
TreeFam 1 0.960
User_Submission 00.000 Not matched by this tool.
98.930

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