Protein Alignment: PIP4K2C and PIP4K

• Sequence 1: NP_001139730.1
• Gene: PIP4K2C
• HGNCID: 23786
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_001033805.1
• Gene: PIP4K
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Alignment Length: 410
• Identity: 210/411 (51%)
• Similarity: 274/411 (67%)
• Gaps: 47/411 (11%)

Human    29 KKKHF--VQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHR 91
            |||||  ..||||:|||.:|::.||:||:.|:|||||.|..|||||||||:|.|||||:||||::
  Fly    15 KKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAYSKIKVDNHLFNK 79

Human    92 ENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFLISYDRTLVIKE 153
            ||:|||||.|||||.||||||:|||:||.||..||||:.|  .:|.|..| :|..|||:..:||.
  Fly    80 ENMPSHFKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKS 144

Human   154 VSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYD 218
            ::||:|..||:.|..||.|:|:.||.|||||:|||||::|::...|.:||||:||..|.:|:|:|
  Fly   145 LTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFD 209

Human   219 LKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSL 283
            ||||.|.||||:||..|.|||.||.||:.:..|:.||:|.|...::.|..||:.|.:|.||||||
  Fly   210 LKGSTVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSL 274

Human   284 LLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVG----------------SYGTSPEGI 332
            |:|:||.:|.   ||||        :.||..||     ||                :|.|.|:..
  Fly   275 LVGVHDCVRA---EEEA--------LQGDNILT-----VGRSENSESEECDSGERWTYNTPPDSP 323

Human   333 GGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAG 397
            .|..:.       |....:|:|.|.|.|  .::|:||:.:||:||||..||:||.||||||:|:.
  Fly   324 RGAQYK-------EVVYEVDIYDIPSIE--EKREIYFIAIIDVLTQYGVKKQAAKAAKTVKYGSN 379

Human   398 AE-ISTVHPEQYAKRFLDFI 416
            .: |||..|||||||||||:
  Fly   380 VDGISTCDPEQYAKRFLDFM 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K2C	NP_001139730.1	PIPKc	72..420	CDD:214623	182/366 (50%)
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	198/394 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG5253
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	455	1.000	Inparanoid score	I1569
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1562683at2759
OrthoFinder	1	1.000				FOG0000924
OrthoInspector	1	1.000				T609413
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR23086
Phylome	1	0.910		0.857	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	9	8.930