Protein Alignment atp8a1 and CG33298

DIOPT Version :10

• Sequence 1: XP_073778311.1
• Gene: atp8a1 / 767630
• ZFINID: ZDB-GENE-060929-36
• Length: 1173
• Species: Danio rerio
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1313
• Identity: 406/1313 - (30%)
• Similarity: 638/1313 - (48%)
• Gaps: 282/1313 - (21%)

Zfish    48 KFCSNRVSTAKYNVLTFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRWTTLVPLLFILVVA 112
            :|..|::.|.||.:|:|:|:.|..||.|.||.:|:||.||..:|::|..|:...::|:||:|.|.
  Fly   249 QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVT 313

Zfish   113 AVKEIIEDLKRHNADNVVNKKETQVL--RNGAWEIVHWEKVSVGEIVRAANGDHLPADLIILSSS 175
            |||::.||.:|..:|..:|....:|.  ....::.|.|:::.||:||..:|.:.:|||:::|.:|
  Fly   314 AVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTS 378

Zfish   176 EPQGMCYIETSNLDGETNLKIRQGLTITTDIKDIDGLMRLSGRMECESPNRHLYEFVGNIRLDGH 240
            :|||:|||:|.:||||||||.|:.:....:::.|....:...|:|.::|...||.|.|.:.....
  Fly   379 DPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTG 443

Zfish   241 GTVPLGPDQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTRPPLKLSNVERITNFQILVLFGCL 305
            ..||:..:.:|||.::|:||.::.|||||.||:||.|.|::.|..|.|.||:..|..::.....|
  Fly   444 ERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIIL 508

Zfish   306 LAISLVCSIGQTIWKYQFGNDAWYMDLNYGGAANFGLN------FLTFIILFNNLIPISLLVTLE 364
            |.:.:|.:||..:|...|    .:..:.|........|      |.|:|::...:||:||.||:|
  Fly   509 LILCVVGAIGCRMWLSSF----THFPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIE 569

Zfish   365 VIKFVQAFFINWDTDMLYEATNTPAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGV 429
            :.|.:|.|.|:.:.|:....||.....|..|:.|||||:::||:|||||||.|.|.|::|.:.|.
  Fly   570 LCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGS 634

Zfish   430 AYGHSSQSTE----ETGFNDPSLL--ENLQSN----------HPTAPVIMEFMTMMAICHT---- 474
            .|.|.....|    :.|...|.|:  :||.|:          .|.|..|.||:.::|||:|
  Fly   635 DYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVG 699

Zfish   475 AVPER------------------------------------------------------------ 479
            |.|.|
  Fly   700 AAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADR 764

Zfish   480 ----------------------------------------------------------------- 479
                                                                             
  Fly   765 YIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPT 829

Zfish   480 ----------------------------------------TDNRITYQAASPDEGALVRAAQNLG 504
                                                    .|.|..|:|.||||.|||.||.:..
  Fly   830 GRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYD 894

Zfish   505 FVFSGRTPDSVIVE--SLEAEEKYELLHVLEFTSTRKRMSVIMR-TPAGKIRLYCKGADTVIYER 566
            .....|:|:.::|.  ...|..:||:|.||.|.|:||.||:::| ..:.:|.||.||||:.|...
  Fly   895 CCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPV 959

Zfish   567 LADSSR------YKDITLKHLEQFATEGLRTLCFAVADISESSYQQWLEVYHRASTSLQNRALKM 625
            |...|.      .::.|.:.|:::|.||||.|..|...::.:.|..|...:.....||:||..::
  Fly   960 LVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRL 1024

Zfish   626 EESYELIEKNLQLLGATAIEDKLQDKVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLTKN 690
            .:|:..:|.||.|||||.|||:|||.|||||.:|:.|.|.:|:|||||.||||||.:|.||.|:.
  Fly  1025 RDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQ 1089

Zfish   691 MGLLVINEDTLDG----------------TRETLSHHCGMLGDALHKENDFALIIDGKTLKYALT 739
            |.|:.:...:.|.                |..||.:     |.:|.|:.. ||::|||||.:.|.
  Fly  1090 MELIRLTARSRDAAETAINFYLTDMENDKTTSTLGY-----GQSLRKKQR-ALVVDGKTLTFILD 1148

Zfish   740 FGARQY--FLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVITLAIGDGANDVGMIQTAHVGVG 802
            ..::..  ||.|:..|.:|:|||.:||||:.:|::||:::.:.|||||||||||.|||.|.||||
  Fly  1149 PKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVG 1213

Zfish   803 ISGNEGLQAANSSDYSIAQFKYLKNLLLVHGAWNYNRVAKCILYCFYKNIVLYIIEIWFAFVNGF 867
            |||.||:||..::|:::.:|:||:.|||.||.|.|:|:::.|||.||||.....:..|:....||
  Fly  1214 ISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGF 1278

Zfish   868 SGQILFERWCIGLYNVIFTALPPLTLGIFERSCRKENMLKYPELYKTSQNAMGFNTKVFWAHCLN 932
            |||::.::..:.|||:|||:||||.:|::::...::.:||.|.|||..:..:.:....||...|:
  Fly  1279 SGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLD 1343

Zfish   933 GLFHSVILFWFPLKAFQHDTV----FGNGKTPDYLLLGNMVYTFVVITVCLKAGLETSSWTMFSH 993
            .|:.|:::|:..|.|:....|    ||...|.. .|..|:|:          ..:|..|||:...
  Fly  1344 ALYQSLVIFFVALCAYAESDVGIWEFGTTITAS-CLFANLVH----------CAIEIRSWTVLHV 1397

Zfish   994 IAIWGSIGLWVVF-----------FGIYSSLWPLIPLAPDMSGEADMMFSSGVFWMGLIFIPITS 1047
            ::|..|:|.:.:|           ||:.||.|.:.           :.|:|.|.|   :.|.:::
  Fly  1398 LSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIF-----------VCFASAVHW---LVIMLST 1448

Zfish  1048 LVFDVAYKVMKKVCFKTLVDEVQELEALSKDPGAVVHGKSLTERAQLLKNVFKKST--VSLYR-S 1109
            :|..:...::..|......|:..::         ::..|....|.:.|...:.:||  .|:|| :
  Fly  1449 VVAVLPRLLLTTVRISLCPDDSTKV---------ILQSKRERSRGEALLVTWSRSTSASSIYRIT 1504

Zfish  1110 DSMQQNLLRTSAT 1122
            |...:|.:.|:.|
  Fly  1505 DYGSKNQIITTIT 1517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atp8a1	XP_073778311.1	None
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	363/1112 (33%)