Protein Alignment CG42402 and EVA1C

DIOPT Version :10

• Sequence 1: NP_001287642.1
• Gene: CG42402 / 7354470
• FlyBaseID: FBgn0259821
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_478067.2
• Gene: EVA1C / 59271
• HGNCID: 13239
• Length: 441
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 104/580 - (17%)
• Similarity: 198/580 - (34%)
• Gaps: 183/580 - (31%)

  Fly    14 PQPLRH----RVVLIGWALIWTMSLNSVFCGEKLA-------LLSATLRTYQKAACDSDQVLIAC 67
            |||::|    |.|.....|:.......:.|.::::       .|:..|:.:...|||.|.:.:.|
Human    13 PQPVQHPGLRRQVEPPGQLLRLFYCTVLVCSKEISALTDFSGYLTKLLQNHTTYACDGDYLNLQC 77

  Fly    68 PRGTSISIEFAQYNKFVAKDGYSIEELCPGSGEIRSEIRGRTKHLLRGSIFGSPPLKTPSSKYMT 132
            ||.::||::.|.|.:     .|   ::|
Human    78 PRHSTISVQSAFYGQ-----DY---QMC------------------------------------- 97

  Fly   133 AGHSLAVPVQSVPEFNSSSATSSESISSVSPSVDDIQSTDYNTDNASENCMWPNALQYSLLQTVV 197
                                :|.:..|....|:..:.:|.:                    |.|:
Human    98 --------------------SSQKPASQREDSLTCVAATTF--------------------QKVL 122

  Fly   198 EACQKKKHCKFHGSPEFYGQGSSGVGDSSGTSSYHSSTASSNAISNDPCPKRKKIVEVAYKCRPY 262
            :.||.::.|..                          ..:|.....|.||...|.:.|::||:|.
Human   123 DECQNQRACHL--------------------------LVNSRVFGPDLCPGSSKYLLVSFKCQPN 161

  Fly   263 EFRSKVACHNDVAQLECNPYSRIAVYSASFG-RTEYESIQCPQPQGVREETCLASYATETVMQIC 326
            |.::|..|.:...:|.|:....:.:|||::| ||:...|...:.:.:....||:..|.:.:.:.|
Human   162 ELKNKTVCEDQELKLHCHESKFLNIYSATYGRRTQERDICSSKAERLPPFDCLSYSALQVLSRRC 226

  Fly   327 HGRRRCNLAADANTFGSPCQPNSRMYLKVVYTCVPKQVLKENKALEVEADESEDFGGDLNDLYDD 391
            :|::||.:..:.:.|||||.|..:.||.|.|.||||.:|
Human   227 YGKQRCKIIVNNHHFGSPCLPGVKKYLTVTYACVPKNIL-------------------------- 265

  Fly   392 ELIYKESEAIPKLYSNTTTTVRQNGTRSLGLGFSVNSANNQSITNSSLVVEGDRSDVNPVMTHSA 456
                   .||....:|...:::|....   .|.:.:.:.::.:....::|....:....:..|
Human   266 -------TAIDPAIANLKPSLKQKDGE---YGINFDPSGSKVLRKDGILVSNSLAAFAYIRAH-- 318

  Fly   457 DLSLEEDQERLYFYLLALVSLGVLISIVIFGTRIALQKHHLVTETLSSSFAKTTRRVEETTIPSG 521
                   .||.....::.|.:|:.:::.....|.:..|.....:.........:.:|||.:....
Human   319 -------PERAALLFVSSVCIGLALTLCALVIRESCAKDFRDLQLGREQLVPGSDKVEEDSEDEE 376

  Fly   522 LNDTISEIDAEIDL----KTTLPL----------PNLSNKENYLTYA-PTSSLYADLPRN 566
            ..:..||.|...:|    :|:.|:          ..:..:|..:... ..|.|...||||
Human   377 EEEDPSESDFPGELSGFCRTSYPIYSSIEAAELAERIERREQIIQEIWMNSGLDTSLPRN 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42402	NP_001287642.1	Gal_Rha_Lectin	51..261	CDD:459238	30/209 (14%)
		Gal_Rha_Lectin_EVA1_EVA1C_rpt2	264..361	CDD:438686	29/97 (30%)
EVA1C	NP_478067.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		4/9 (44%)
		Gal_Rha_Lectin_EVA1_EVA1C_rpt1	61..160	CDD:438685	30/209 (14%)
		Gal_Rha_Lectin_EVA1_EVA1C_rpt2	164..261	CDD:438686	29/96 (30%)
		FAM176	301..441	CDD:464347	24/145 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	362..390		6/27 (22%)