DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment C1R and CG9631

DIOPT Version :9

Sequence 1:	NP_001341275.1	Gene:	C1R / 715	HGNCID:	1246	Length:	719	Species:	Homo sapiens
Sequence 2:	NP_650345.1	Gene:	CG9631 / 41729	FlyBaseID:	FBgn0027563	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	77/289 - (26%)
Similarity:	120/289 - (41%)	Gaps:	56/289 - (19%)

- Green bases have known domain annotations that are detailed below.

Human   458 IPRCLP-------VCG-KPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGG------ALLGD 508
            :|..:|       .|| :..:|::     |||.....|.:|| :.....|.|..      :::..
  Fly   174 LPSIMPRIDSDFEECGVEGFSPLQ-----IGGDLVTRGQYPW-LAALYEGVGTATYKCVVSVISK 232

Human   509 RWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIA 573
            |.::||||.:|.|     |.:.|.|:||..:..|..:.|...:...||......:.:...:.|:.
  Fly   233 RTVITAAHCIYGK-----SASQLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEGNPVPDADVG 292

Human   574 LLELENSVTLGPNLLPIC-------LPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRF-----VRL 626
            ||.|.:.:.....:.|:|       ||.|:     |..|.|:|:|.  ::.|...||     |||
  Fly   293 LLVLTSPMVYTKYIRPLCLWGSNMGLPPNE-----GDTGAVAGWGY--DRSAQKTRFPKTVSVRL 350

Human   627 PVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVS-- 689
             |...|..:...|.:   |..::...|||: |.....|.||||....|...|  ||...|:||
  Fly   351 -VPRDQCLKEMKRAE---DFITRRTVCAGN-SESHGPCFGDSGSALIVLRNN--RWYVRGVVSLS 408

Human   690 --WGIGCSRG-YGFYTKVLNYVDWIKKEM 715
              .|..|... |..|..|..::||:::.|
  Fly   409 PRHGEICDLSKYVIYCDVARHIDWVRQNM 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:317114
		CUB	207..316	CDD:278839
		Sushi	323..385	CDD:306569
		Sushi	390..461	CDD:306569	1/2 (50%)
		Tryp_SPc	477..711	CDD:214473	70/256 (27%)
CG9631	NP_650345.1	GD_N	26..127	CDD:292649
		Tryp_SPc	198..436	CDD:238113	71/257 (28%)
		Tryp_SPc	198..433	CDD:214473	70/254 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910