DRSC/TRiP Functional Genomics Resources

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Protein Alignment C1R and CG11529

DIOPT Version :9

Sequence 1:NP_001341275.1 Gene:C1R / 715 HGNCID:1246 Length:719 Species:Homo sapiens
Sequence 2:NP_648558.1 Gene:CG11529 / 39395 FlyBaseID:FBgn0036264 Length:287 Species:Drosophila melanogaster


Alignment Length:256 Identity:78/256 - (30%)
Similarity:116/256 - (45%) Gaps:45/256 - (17%)


- Green bases have known domain annotations that are detailed below.


Human   479 IGGQK-AKMGNFPWQVFTNIHGRG--------GGALLGDRWILTAAHTLYPKEHEAQSNASLDVF 534
            :|..| .::..||:||.  :.|:.        ||.||..||||||.|......|       .||:
  Fly    30 VGQSKYGRIEKFPYQVM--LIGKQLWRKRILCGGTLLDKRWILTAGHCTMGVTH-------YDVY 85

Human   535 LGHTNVEELMKLGNHPIR--RVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPD--- 594
            ||..:||:....|...:|  :..||..:..:.:.|   ||||::|...|...|.:.|..||.   
  Fly    86 LGTKSVEDTEVSGGLVLRSNKFIVHERFNPETAAN---DIALVKLPQDVAFTPRIQPASLPSRYR 147

Human   595 NDTFYDLGLMGYVSGFGVMEEKIAHD-LRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPS 658
            :|.|  .|:....||:|.|.|....| :::..|.|.:...|      ....||.:..:.||  ..
  Fly   148 HDQF--AGMSVVASGWGAMVEMTNSDSMQYTELKVISNAEC------AQEYDVVTSGVICA--KG 202

Human   659 LKQD-ACQGDSGGVFAVRDPNTDRWVATGIVSWG--IGCSRGY-GFYTKVLNYVDWIKKEM 715
            ||.: .|.|||||...::|..    :..||.|:|  .||.... |.:|:|.:|:|||:.::
  Fly   203 LKDETVCTGDSGGPLVLKDTQ----IVVGITSFGPADGCETNIPGGFTRVTHYLDWIESKI 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
C1RNP_001341275.1 CUB 41..152 CDD:214483
FXa_inhibition 175..203 CDD:317114
CUB 207..316 CDD:278839
Sushi 323..385 CDD:306569
Sushi 390..461 CDD:306569
Tryp_SPc 477..711 CDD:214473 76/250 (30%)
CG11529NP_648558.1 Tryp_SPc 37..258 CDD:238113 76/246 (31%)
Tryp_SPc 37..255 CDD:214473 74/243 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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