DRSC/TRiP Functional Genomics Resources

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Protein Alignment C1R and zetaTry

DIOPT Version :9

Sequence 1:NP_001341275.1 Gene:C1R / 715 HGNCID:1246 Length:719 Species:Homo sapiens
Sequence 2:NP_523691.1 Gene:zetaTry / 36216 FlyBaseID:FBgn0011556 Length:280 Species:Drosophila melanogaster


Alignment Length:264 Identity:72/264 - (27%)
Similarity:110/264 - (41%) Gaps:57/264 - (21%)


- Green bases have known domain annotations that are detailed below.


Human   477 RIIGGQKAKMGNFPWQVFTNIHG----------RGGGALLGDRWILTAAHTL---YPKEHEAQSN 528
            ||:||....:...|:|:.....|          |.||::..:..|:||||.:   ...:::..:.
  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVASQYKVVAG 102

Human   529 ASLDVFLGH----TNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELE-----NSVTLG 584
            .:...  |.    |||:|::           :|..|....:||  .|||:|.::     |:.|:.
  Fly   103 TNFQT--GSDGVITNVKEIV-----------MHEGYYSGAAYN--NDIAILFVDPPLPLNNFTIK 152

Human   585 PNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLR--GKNRMD 645
            ...|.:..|..      |.:..|||:|....  ..::.|..|.:|:.:.:.|:....  |.....
  Fly   153 AIKLALEQPIE------GTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYR 211

Human   646 VFSQNMFCAGHPSL-KQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCS-RGY-GFYTKVLNY 707
            :.|. |.|||...: ..|||||||||..||||.      ..|:||||..|: ..| |.|..|...
  Fly   212 ITSA-MLCAGKRGVGGADACQGDSGGPLAVRDE------LYGVVSWGNSCALPNYPGVYANVAYL 269

Human   708 VDWI 711
            ..||
  Fly   270 RPWI 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
C1RNP_001341275.1 CUB 41..152 CDD:214483
FXa_inhibition 175..203 CDD:317114
CUB 207..316 CDD:278839
Sushi 323..385 CDD:306569
Sushi 390..461 CDD:306569
Tryp_SPc 477..711 CDD:214473 70/262 (27%)
zetaTryNP_523691.1 Tryp_SPc 38..273 CDD:214473 70/262 (27%)
Tryp_SPc 39..276 CDD:238113 71/263 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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