Protein Alignment C1R and CG31267

DIOPT Version :10

• Sequence 1: NP_001341275.1
• Gene: C1R / 715
• HGNCID: 1246
• Length: 719
• Species: Homo sapiens
• Sequence 2: NP_732214.1
• Gene: CG31267 / 318651
• FlyBaseID: FBgn0051267
• Length: 275
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 66/264 - (25%)
• Similarity: 109/264 - (41%)
• Gaps: 71/264 - (26%)

Human   477 RIIGGQKAKMGNFPWQV-FTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHT 538
            ||:||:::.:...|:.| ..|.:|..  .|:::.|:|::|||..|              ..|...
  Fly    44 RIVGGEESDVLAAPYLVSLQNAYGNHFCAGSIIHDQWVITAASCL--------------AGLRKN 94

Human   539 NVEELMKLGNH--------PIRRVSVHPDYRQDESYNFEGDIALLELE-----NSVTLGPNLLPI 590
            ||:.:....||        .:..:.:|.::   :|..:..||||::..     :.||....:.|:
  Fly    95 NVQVVTTTYNHWGSEGWIYSVEDIVMHCNF---DSPMYHNDIALIKTHALFDYDDVTQNITIAPL 156

Human   591 -CLPDNDTFYDLGLMGYVSGFGVMEEKIAHD----LRFVRLPVANPQACENWLRGKNRMDVFSQN 650
             .|.|.:|   |.:.||.|      .:|..|    |:.:.:....|:.|.....|...:||
  Fly   157 EDLTDGET---LTMYGYGS------TEIGGDFSWQLQQLDVTYVAPEKCNATYGGTPDLDV---- 208

Human   651 MFCAGH----PSLKQDACQGDSGGVFAVRDPNTD-RWVATGIVSWGIGCSRGYGF---YTKVLNY 707
                ||    ..:...||.||:||      |..| |....|:.:||:.|  ||||   :.::..|
  Fly   209 ----GHLCAVGKVGAGACHGDTGG------PIVDSRGRLVGVGNWGVPC--GYGFPDVFARISFY 261

Human   708 VDWI 711
            ..||
  Fly   262 YSWI 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:464251
		CUB	207..316	CDD:395345
		Sushi	323..385	CDD:459664
		CCP	390..461	CDD:153056
		Tryp_SPc	477..711	CDD:214473	64/262 (24%)
CG31267	NP_732214.1	Tryp_SPc	44..265	CDD:214473	64/262 (24%)