Protein Alignment C1R and CG32260

DIOPT Version :9

• Sequence 1: NP_001341275.1
• Gene: C1R / 715
• HGNCID: 1246
• Length: 719
• Species: Homo sapiens
• Sequence 2: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 125/527 - (23%)
• Similarity: 197/527 - (37%)
• Gaps: 172/527 - (32%)

Human   256 IDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT-- 318
            ||..||.:.|.    :.:.|..||.        |:        ::|....||..|..:.|..:
  Fly   151 IDPRQQQNSPL----LSSTGPQIGS--------DM--------MVFMPLNSGRRRRRRRRPQSCQ 195

Human   319 ----------EIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSF--TAV 371
                      .:..|||            |..:||.               :.|: .|:|  .::
  Fly   196 DARSRPGSCLPLTSCPQ------------LMQEYQG---------------QANE-FHTFLGQSI 232

Human   372 CQDDGTWHRAMPRCKIKDCGQPRN---------LPNGDFRYTTTMGVNTYKARI----------- 416
            |..||:  ..|..|.....|..|:         .|.|.|.::...|.:|....:
  Fly   233 CGFDGS--TFMVCCATDRSGNARSRKDVFVTTAAPFGFFHFSPLSGGSTATPMVFQPTPPLSQVV 295

Human   417 --QYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRII 479
              .:|...|  ........|||.    ||...|...|                         |::
  Fly   296 SPSFYPPPP--PPPPNNAPRESA----TCGISGATSN-------------------------RVV 329

Human   480 GGQKAKMGNFPWQV---FTNIHGRG------GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 535
            ||.:|:.|.:||..   :...:.|.      ||:|:..|:::|:||.:.|
  Fly   330 GGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINP--------------- 379

Human   536 GHTNVEELMKLGNHP-------------IRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNL 587
                :..|::||.|.             |||..||..:   :..:...||||:||.....|..|:
  Fly   380 ----MLTLVRLGAHDLSQPAESGAMDLRIRRTVVHEHF---DLNSISNDIALIELNVVGALPGNI 437

Human   588 LPICLPDNDTFYD---LGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVF 647
            .|||||:...|..   :|:..:|:|:|.::.:  .:..||..::|:.:..:||...:...:...|
  Fly   438 SPICLPEAAKFMQQDFVGMNPFVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFVQF 502

Human   648 SQNMFCAGHPSLKQDACQGDSGG--VFAVRDPNTDRWVATGIVSWGIGCSRGY--GFYTKVLNYV 708
            |..:.|||..|:  |||||||||  :....:.|..|:...|:||:|..|:|..  |.||:|.:||
  Fly   503 SDKVLCAGSSSV--DACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVASYV 565

Human   709 DWIKKEM 715
            .||||.:
  Fly   566 PWIKKHI 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:317114
		CUB	207..316	CDD:278839	13/59 (22%)
		Sushi	323..385	CDD:306569	13/63 (21%)
		Sushi	390..461	CDD:306569	16/92 (17%)
		Tryp_SPc	477..711	CDD:214473	77/264 (29%)
CG32260	NP_728942.1	CLIP	194..244	CDD:288855	13/79 (16%)
		Tryp_SPc	327..568	CDD:214473	77/264 (29%)
		Tryp_SPc	328..571	CDD:238113	79/266 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910