DRSC/TRiP Functional Genomics Resources

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Protein Alignment C1R and CG33458

DIOPT Version :9

Sequence 1:NP_001341275.1 Gene:C1R / 715 HGNCID:1246 Length:719 Species:Homo sapiens
Sequence 2:NP_995854.2 Gene:CG33458 / 2768846 FlyBaseID:FBgn0053458 Length:281 Species:Drosophila melanogaster


Alignment Length:254 Identity:68/254 - (26%)
Similarity:108/254 - (42%) Gaps:34/254 - (13%)


- Green bases have known domain annotations that are detailed below.


Human   477 RIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTN 539
            ||.||:.:.:...||..:.:|:.:  .||:||...::|||||....|      ||.:.|.||..:
  Fly    37 RITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDK------NAKVLVRLGEND 95

Human   540 VEELMKLG---------NHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL--- 592
            ..:.:...         .:.|.:..:||.||....|    ||||.:|...|....::.||||   
  Fly    96 ASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHYY----DIALAKLNRYVVYTDSIRPICLMLN 156

Human   593 PDNDTFYDLGLMGYVSGFGVME-EKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGH 656
            |:...:.|......::|:|... .:::..|:..|:|..:...|..|..     .:..:...|||.
  Fly   157 PNWQVYVDTIRYFIITGWGATNASEVSDKLQLTRIPQIDRFTCRYWFG-----YMVDRTHICAGE 216

Human   657 PSLKQDACQGDSGGVFA--VRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKK 713
            .  |....:|||||...  |......|:...||||.......|...:|.:|:|.:||.:
  Fly   217 S--KHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSHLRQPFHGVSVFTNILSYSNWIHR 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
C1RNP_001341275.1 CUB 41..152 CDD:214483
FXa_inhibition 175..203 CDD:317114
CUB 207..316 CDD:278839
Sushi 323..385 CDD:306569
Sushi 390..461 CDD:306569
Tryp_SPc 477..711 CDD:214473 66/250 (26%)
CG33458NP_995854.2 Tryp_SPc 37..271 CDD:214473 66/250 (26%)
Tryp_SPc 38..274 CDD:238113 67/253 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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