Protein Alignment C1R and CG43110

DIOPT Version :9

• Sequence 1: NP_001341275.1
• Gene: C1R / 715
• HGNCID: 1246
• Length: 719
• Species: Homo sapiens
• Sequence 2: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 76/270 - (28%)
• Similarity: 108/270 - (40%)
• Gaps: 66/270 - (24%)

Human   465 CGKPVNPVEQRQRIIGGQKAKMGNFPWQ--VFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQS 527
            |||...|     :||.|..|...:..:.  :|...|...||.::.:.::||.||        .:|
  Fly    28 CGKTPVP-----KIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAH--------CKS 79

Human   528 NASLDVFLGHTNVEELMKLGNHPIRRVSV-----HPDYRQDESYNFEGDIALLELENSVTLGPNL 587
            ..:|.|.||..|:       |||..::.|     ||.|   .:..:..||||::||.||....|:
  Fly    80 TQTLFVRLGAYNI-------NHPTDQIRVIETIAHPQY---SNSTYANDIALVKLERSVIFNLNI 134

Human   588 LPICLPDNDTFYDLG-LMGYVSGFGVMEEKIAHD---LRFVRLPVANPQACENWLRGKNRMDVFS 648
            .|||:..:.|   || .:.|.:.||....:.|..   |:.:.:...||..|
  Fly   135 QPICIHLDAT---LGKQIRYYNAFGWGRTRNAEQSDILQRIFVNRTNPMIC-------------- 182

Human   649 QNMFCAGHPSLKQ--------DACQGDSGG----VFAVRDPNTDRWVATGIVSWGIGCSRGYGFY 701
             :::....|..||        |.|.|||||    ....:..|.|  ...||.|:|.....|.|.|
  Fly   183 -HLYLGMSPDPKQICATTDQGDTCAGDSGGPLISKITYQGKNFD--TQFGITSYGTRECNGVGLY 244

Human   702 TKVLNYVDWI 711
            |.|..|..||
  Fly   245 TDVSQYSGWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C1R	NP_001341275.1	CUB	41..152	CDD:214483
		FXa_inhibition	175..203	CDD:317114
		CUB	207..316	CDD:278839
		Sushi	323..385	CDD:306569
		Sushi	390..461	CDD:306569
		Tryp_SPc	477..711	CDD:214473	70/256 (27%)
CG43110	NP_001246396.1	Tryp_SPc	35..254	CDD:214473	70/256 (27%)
		Tryp_SPc	36..257	CDD:238113	72/257 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910