Protein Alignment Atp8b5 and CG33298

DIOPT Version :10

• Sequence 1: XP_038966915.1
• Gene: Atp8b5 / 691125
• RGDID: 1587460
• Length: 1191
• Species: Rattus norvegicus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1293
• Identity: 401/1293 - (31%)
• Similarity: 636/1293 - (49%)
• Gaps: 274/1293 - (21%)

  Rat    51 EYPDNSIKTSKYSFFNFLPVNLFEQFQRLANAYFLILLFLQLIPQISSLAWYTTVIPLIVVLSIT 115
            ::..|.|:|:||:..:|:|.||.|||.|:||.||:.::.|..:|:||:......:||::.||.:|
  Fly   249 QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVT 313

  Rat   116 GVKDAIDDVVKWLPGLPSLHLKRHQSDQQVNNRSVLILVNG---RIEENKWRNVQVGDIIKLEND 177
            .|||..:|            .:|..||:::||.:..: .:|   |.::.||:.::||||:.|.|:
  Fly   314 AVKDLFED------------RRRRASDKRINNTTCRV-YDGETERYKKVKWQELRVGDIVHLSNN 365

  Rat   178 HPVTADVLLLSSSEPYGLTYIETADLDGETNLKVKQAVSATSDMEDNLELLSAFNGEVRCEPPNN 242
            ..|.||:|||.:|:|.|:.||:|.|||||||||.::.|....:|: ::.:.|.|...|..:.|..
  Fly   366 ETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQ-SIFVPSKFVSRVEADAPTT 429

  Rat   243 KLDRFSGTLSY-LGDTYFLDYERLLLRGCIIRNTDWCYGLVVYTGPDTKLMQNSGRSTFKRTHID 306
            ||.||.|.|.: .|:...:..|.||||...::|||:..|:|||.|.:||.|.|:....:||:.::
  Fly   430 KLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVE 494

  Rat   307 HLMNVLVLWIFMLLGGMCFLLSIGHGIWESNRGYHFQAFLPWERYITSSAASSALAFWSYFIVLN 371
            ..||:.|:|..::|..:|.:.:||..:|.|:..:....:||..: :|::..|..: ||:|.::|.
  Fly   495 QQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNK-LTANMESMWI-FWTYIVILQ 557

  Rat   372 TMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNTPAQARTTTLNEELGQVEYVFSDKTGTLTEN 436
            .|:|:||||::|:.::...::|:.:..:|.|..|...:.|...:.|||||::::|:|||||||||
  Fly   558 VMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTEN 622

  Rat   437 VMIFNKCSINGKTYGYS-------YDENG-QCVPKSPSNKVDFSYNHLADPKFSFYDKTLVEAVK 493
            .|||.:|.:||..|.:.       |.:.| ...|..|::.::.....|....:          :.
  Fly   623 KMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTY----------LT 677

  Rat   494 SEDPLVYLFFLCLSLCHTVM--------------------------------------------- 513
            .....:..|.:.|::|:||:
  Fly   678 PHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTT 742

  Rat   514 ----------------------------------------------------------------- 513
                                                                             
  Fly   743 TTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPN 807

  Rat   514 SEEK----------------------------------------------------------VEG 520
            ||.:                                                          .:|
  Fly   808 SESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADG 872

  Rat   521 ELVYQAQSPDEGALVTASRNFGFVFHSRTPETITV-IEM-GRVRVYRLLAILDFSNERKRMSVIV 583
            ..:|:|:||||.|||.|:.::.....:|:|..|.| :.| |..|.|.:|.:|.|.:.||.||::|
  Fly   873 RPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVV 937

  Rat   584 -QTPEDRVMLFCKGADTIIYELLHPSCA------ALSDVTMDQLDDFASEGLRTLMVAYRELDKA 641
             |.....::|:.||||:.|..:|.| |:      .|.:.|...||.:|.||||.|::|.|.|:.|
  Fly   938 RQIGSQEIVLYTKGADSSIMPVLVP-CSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSA 1001

  Rat   642 FFQTWIKKHGEAWLTLENREKKLALVYEEIERDLVLLGATAIEDKLQSGVPETIVTLNKAKIKIW 706
            .:..|..:|.|..::|||||::|...:.::|.:|.|||||.|||:||.||||||.:|..|.|.:|
  Fly  1002 DYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVW 1066

  Rat   707 VLTGDKQETAVNIAYSCRIFKDEMDAVFMVEGTDRETVLEELRTARKKMKPESLLESDPINIYLA 771
            ||||||.|||:|||||.::|..:|:.:.:              |||.:...|:     .||.||.
  Fly  1067 VLTGDKPETAINIAYSAKLFTQQMELIRL--------------TARSRDAAET-----AINFYLT 1112

  Rat   772 RKSKMPFKAVDEVPNG-SYG---------LVISGCSLAYALESNTEFEL--LRTACMCKGVVCCR 824
            ....      |:..:. .||         ||:.|.:|.:.|:..::..|  ||.:..|..|:|||
  Fly  1113 DMEN------DKTTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCR 1171

  Rat   825 MTPLQKAQVVDLVKRYKKVVTLAIGDGANDIGMIKAAHIGVGISGQEGMQATLSSDFSFCQFRYL 889
            .||||||.:|.:||....:.||||||||||:.||:.|.:||||||||||||.:::||:..:||||
  Fly  1172 STPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYL 1236

  Rat   890 QRLLLVHGRWSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPI 954
            :||||.||.|.|:|:.:.:.||||||.||..:.|||..:.|||.|.:.|..::..||||:||||.
  Fly  1237 ERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPP 1301

  Rat   955 LGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFIKCLLHGIYSSFVLFFVPMGTVFNSERSD 1019
            |.:.:::|.|.|...|..|.||:.|:..:.:...:|...||..:|.|.|:|||.:.....|
  Fly  1302 LAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAES---- 1362

  Rat  1020 GKDISDFQSFSLLVQTTLIWVMTMQIALSTTYWTMINHAFTWGSLGLYFCILFLLCSDGLCLMFP 1084
              |:..:: |...:..:.::...:..|:....||:::......|||.::  ||.:..|.:|:
  Fly  1363 --DVGIWE-FGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFY--LFAIVYDSVCM--- 1419

  Rat  1085 SVFNFLGVARN------GLNQPQMWLCLVLSSVLCLIPLMGYNFLKPILWPINVDKVL 1136
               |..||..:      .......||.::||:|:.::|.:....::..|.|.:..||:
  Fly  1420 ---NCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVI 1474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp8b5	XP_038966915.1	P-type_ATPase_APLT_Dnf-like	54..1008	CDD:319770	374/1154 (32%)
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	374/1154 (32%)