Protein Alignment Atp8b3 and CG33298

DIOPT Version :9

• Sequence 1: NP_080370.2
• Gene: Atp8b3 / 67331
• MGIID: 1914581
• Length: 1335
• Species: Mus musculus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1347
• Identity: 402/1347 - (29%)
• Similarity: 634/1347 - (47%)
• Gaps: 293/1347 - (21%)

Mouse     9 NLEDKDTEFTWEVKANDRTYHKQFKKKGFLCWRQKKYKSNAIHTAKYNIFSFLPLNLYEQFHRMS 73
            |..||..|.::.....:.|...:..|:..   ...::..|.|.|.||.:.||:|.||.|||||::
  Fly   217 NTGDKFEERSYRTVVPNHTVPPKTPKRDH---PNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVA 278

Mouse    74 NLYFLFIIILQGIPEISTLPWFTLFAPLVCLFVIRATRDLVDDIGRHRSDKIINNRPCQILRGKS 138
            ||||:||::|..:||||.........|::.:..:.|.:||.:|..|..|||.|||..|::..|::
  Fly   279 NLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGET 343

Mouse   139 FLWK--KWKNLCVGDVVCLSKDSIVPADLLLLASTEPSSLCYVETADIDGETNLKFRQALTVTHH 201
            ..:|  ||:.|.|||:|.||.:..||||:|||.:::|..:||::|.|:|||||||.|:.:. ...
  Fly   344 ERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVR-GFE 407

Mouse   202 ELTSPKKMASFQGTVTCEEPNSRMHHFVGSL-EWNSRKYPLDIGNLLLRGCKIRNTDTCYGLVIY 265
            |:.|....:.|...|..:.|.::::.|.|:| .....:.|:....||||..:::|||...|:|:|
  Fly   408 EMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVY 472

Mouse   266 AGLDTKIMKNCGKIHLKRTKLDLMMNKLVALIFLSLVIASLLLTVGFTFMVKQFKAKHY---YMS 327
            ||.:||.|.|......||::::..||..|....:.|:|..::..:|....:..|  .|:   |:.
  Fly   473 AGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSF--THFPVPYLP 535

Mouse   328 PTHGRSDAMESFFIFWGFLILLSVMVPMAMFIIAEFIYLGNSIFINWDLNMYYEPLDMPAKARST 392
            |....:: |||.:|||.::::|.||:|:::::..|...:.....|:.:::::....:...:.|:.
  Fly   536 PNKLTAN-MESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAM 599

Mouse   393 SLNDQLGQVQYIFSDKTGTLTQNIMTFKKCCINGCIYDSDDEHGTLRKRNPYAWNPFADGKLQFY 457
            ::.::|||:|:||:|||||||:|.|.|::|.:||    ||..|........|: .|.|.......
  Fly   600 NITEELGQIQHIFTDKTGTLTENKMIFRRCVVNG----SDYNHPPSELEKIYS-KPGAPAPPLIP 659

Mouse   458 NKELES----LVQGR----QDRAVQEFWRLLAICHTVMV-------------------------- 488
            |..|.|    |.||.    ..:.:|||..:||||:||:|
  Fly   660 NDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPAN 724

Mouse   489 ----------------------------------------------------------------- 488
                                                                             
  Fly   725 LKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQ 789

Mouse   489 ----------------------------------------------------------------- 488
                                                                             
  Fly   790 SHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGK 854

Mouse   489 -------------QEKDNQLLYQAASPDEEALVTAARNFGYVFLSRTQDTITLVEL---GEERVY 537
                         :..|.:.||:|.||||.|||.||.::....|:|:.:.| ||.:   |..|.|
  Fly   855 RMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQI-LVSMPMAGATREY 918

Mouse   538 QVLAMMDFNSVRKRMSVLVRNPEGS--ICLYTKGADTVILERL------RSKGVMEATTEEVLAA 594
            ::|.::.|:|.||.||::||. .||  |.|||||||:.|:..|      ..:|::...|:::|..
  Fly   919 EILKVLPFDSSRKCMSIVVRQ-IGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDR 982

Mouse   595 FAEQTLRTLCLAYKDVEEDAYKEWEPEHQEAALLLQNRAQALHQVYNKMEQNLQLLGATAIEDKL 659
            :|.:.||.|.:|.:.:....|.:|...|||..:.|:||.:.|...:.|:|.||.|||||.|||:|
  Fly   983 YAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRL 1047

Mouse   660 QDGVPETIKCLKKGNIKIWVLTGDKPETAVNIGFACQLLSENMIIL----EDKDINQ-VLERYWE 719
            ||||||||..|....|.:|||||||||||:||.::.:|.::.|.::    ..:|..: .:..|..
  Fly  1048 QDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLT 1112

Mouse   720 DNVHQKAFKMMTHHNMALVINGEFLDQLLLSLRKEPRALVQNAVVDEVAQEPVVSALDFLQKRRI 784
            |..:.|....:.:        |:       ||||:.||||.:.           ..|.|:.
  Fly  1113 DMENDKTTSTLGY--------GQ-------SLRKKQRALVVDG-----------KTLTFIL---- 1147

Mouse   785 SQMWRNAGPSLGTSHSADSKIRESPEVQRERAFVDLASKCQAVICCRVTPKQKALVVALVKKYQQ 849
                                   .|:.:....|:.|:.:|.:|:|||.||.|||.:|.:||:...
  Fly  1148 -----------------------DPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELN 1189

Mouse   850 VVTLAIGDGANDVNMIKTADIGVGLAGQEGMQAVQNSDYVLAQFCYLQRLLLVHGRWSYMRVCKF 914
            :.|||||||||||:||:.||:|||::||||||||..:|:.|.:|.||:||||.||.|.|.|:.:.
  Fly  1190 LRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRM 1254

Mouse   915 LRYFFYKTVASMMAQIWFSLVNGFSAQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVTAEKSLKM 979
            :.|||||..|.:....|:.|..|||.|.:.:..:|.|:||::::||.|.||::::.|..:..||.
  Fly  1255 ILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKN 1319

Mouse   980 PELYMAGQKGELFNYSIFMQAITHGTITSMINFFVTVMVSSDMSKAGSSHDYQSLGVLVAISSLL 1044
            |.||..|:.|..:....|...:......|::.|||.:     .:.|.|.......|..:..|.|.
  Fly  1320 PYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVAL-----CAYAESDVGIWEFGTTITASCLF 1379

Mouse  1045 SVTLEVMLVVKYWTLLFVGAVVLSLSSYVLMTSLTQSLWMYRISPKTFPFLFADYNVLF----EP 1105
            :..:...:.::.||:|.|.::||||.|:.|...:..|:.|.....:      :.|.|:|    ..
  Fly  1380 ANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVR------SSYWVIFVCFASA 1438

Mouse  1106 CSLLLIVLNVALNVLPMLALRTIH---------RTVL---KQRPKGE 1140
            ...|:|:|:..:.|||.|.|.|:.         :.:|   ::|.:||
  Fly  1439 VHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQSKRERSRGE 1485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp8b3	NP_080370.2	P-type_ATPase_APLT_Dnf-like	47..1015	CDD:319770	362/1166 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1192..1215
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1236..1280
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1314..1335
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	362/1166 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-
Hieranoid	0	0.000	Not matched by this tool.