Protein Alignment Nt5el and NT5E-2

DIOPT Version :10

• Sequence 1: NP_080027.1
• Gene: Nt5el / 66763
• MGIID: 1914013
• Length: 585
• Species: Mus musculus
• Sequence 2: NP_611218.1
• Gene: NT5E-2 / 246458
• FlyBaseID: FBgn0050104
• Length: 585
• Species: Drosophila melanogaster
• Alignment Length: 514
• Identity: 129/514 - (25%)
• Similarity: 226/514 - (43%)
• Gaps: 112/514 - (21%)

Mouse    42 ILHFNDVY------DVDSSTEEP--------VGGAARFATAVKRF---------SILNPLLIFSG 83
            |||.||::      .|:|.|..|        .||.||.|..|:::         |:   |.:.:|
  Fly    35 ILHNNDMHARFDQTSVNSGTCPPEDVHTNKCYGGFARVAHEVRKYRKEAQEGGTSV---LYLNAG 96

Mouse    84 DCLNPSILSTITKGKHMISILNELGVHFAVFGNHEFDFGVDILEEYMKQMHF------------- 135
            |....:...||.|.|...:.||:|.......||||||..|:.|..::.::.|
  Fly    97 DTYTGTSWFTIFKDKIASAFLNKLKPDAISLGNHEFDERVEGLIPFLNEVTFPVLACNLDLSKVP 161

Mouse   136 ----TWFLSNVHDRFTSEPLGHGAVKKIVNWNNRKIGLMGLVEEDWLDTLATVNKANVNYKDYVE 196
                ||.|:|               ..|:..|..|:|::|.:..   ||.......:|.:.:.||
  Fly   162 QLKATWHLAN---------------SAILETNGTKVGVIGYLTP---DTKKLTLNMDVEFNEEVE 208

Mouse   197 TANELAVELRAEGADLVIAMTHMKWKNDTRLAQHAEGLDLILGGH-------------DHEYG-- 246
            :.|..|.:|:|:|..::||:.|..:..|..:|::...:|:::|||             :|..|
  Fly   209 SINVEAKKLKAQGIKIIIALGHSGYLKDLEIAKNCPEVDIVIGGHTNTFLYTGAQPDAEHIDGPY 273

Mouse   247 --IKKVN---ETWIVKSGSDFKNLTKIDIQLFDAS---FQYVFEKVEILSYLEEDSYIKAIVRDF 303
              :.|.|   |..:|::.:..|.|.|:.:| |||.   .|:....:.:.:.:.::..:..::..|
  Fly   274 PTMVKQNSGKEVPVVQAYAYTKYLGKLHVQ-FDADGNLIQWDGSPILLNASVAQEQDLLDLLEVF 337

Mouse   304 TQNIQYMLEEVLCPIDVALDGREITVRRCESNLGNLVTNAMLEA-----------THADVALLNS 357
            ..|:..:.:.|:....|.|:|.:...|..|.|||||:.:||:.:           |.|.::::..
  Fly   338 RPNVTRLEKSVVGHTKVHLEGNKAVCRAEECNLGNLIADAMVFSRLMEEQGGDFWTDAAISIMQG 402

Mouse   358 GTLRYD-RIHPPGNFTLHDLLAILPIVDPVLVVRATGAQLLEALENGVYKYPAL-----DGRFPQ 416
            |.:|.. .....|..|.:|:|::||..:.:.:|..||:.:..|||:|.    ||     ||.|.|
  Fly   403 GGIRSSIEKRSDGAITDNDILSVLPWGNKLYMVPMTGSTIRRALEHGA----ALRGKDSDGGFLQ 463

Mouse   417 VAGLEFGFDPDAEPGHRVIRDTVKVQG------QYLQRKKVYLLAIKEYIANGKDGYSM 469
            |:|:...|:.:...|.||:...|:...      ..|....:|.:.:.|::.:|.||:.|
  Fly   464 VSGIRVVFNSNKPEGQRVVSVQVRCAACRVPTYSDLNDTAIYNVVLGEFLLDGGDGHVM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nt5el	NP_080027.1	MPP_CG11883_N	40..293	CDD:277351	77/313 (25%)
		ushA	104..496	CDD:236566	106/429 (25%)
NT5E-2	NP_611218.1	MPP_CD73_N	33..320	CDD:277354	77/306 (25%)
		5_nucleotid_C	348..519	CDD:427027	47/174 (27%)