DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nmnat1 and Nmnat

DIOPT Version :10

Sequence 1:NP_597679.1 Gene:Nmnat1 / 66454 MGIID:1913704 Length:285 Species:Mus musculus
Sequence 2:NP_651315.2 Gene:Nmnat / 42987 FlyBaseID:FBgn0039254 Length:389 Species:Drosophila melanogaster


Alignment Length:257 Identity:117/257 - (45%)
Similarity:163/257 - (63%) Gaps:20/257 - (7%)


- Green bases have known domain annotations that are detailed below.


Mouse     9 VVLLACGSFNPITNMHLRLFELAKDYMHATGKYSVIKGIISPVGDAYKKKGLIPAHHRIIMAELA 73
            :..:|||.|:|.|.||||:||:|||:....|.:.|:.|||||..|:|.||||..|..|..|.:||
  Fly    46 IAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLASALDRCAMVKLA 110

Mouse    74 TKNSHWVEVDTWESLQKEWVETVKVLRYHQEKL-----ATGSCSYPQSSPALEKPGRKRKWADQK 133
            |::|:|:.:..||..|.:|:.|..||::||..:     :.|.......:..|  ||    |..:.
  Fly   111 TQSSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHL--PG----WLPRG 169

Mouse   134 QDSSPQKPQEPKPTGVPKVKLLCGADLLESFSVPNLWKMEDITQIVANFGLICITRAGSDAQKFI 198
            ...|    ::|     ..:||||||||||||:||.||...||..||||.||:.||||||:..|||
  Fly   170 LHDS----RDP-----VHLKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFI 225

Mouse   199 YESDVLWRHQSNIHLVNEWITNDISSTKIRRALRRGQSIRYLVPDLVQEYIEKHELYNTESE 260
            ::||:|.::||||.|:..|:.|::|||.|||.|.||||::||:.|||.|||::..|:|.:|:
  Fly   226 FDSDILTKYQSNITLITNWVPNEVSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRLFNFKSK 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nmnat1NP_597679.1 NMNAT_Eukarya 9..255 CDD:185681 114/250 (46%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 109..149 7/39 (18%)
Nuclear localization signal. /evidence=ECO:0000255 123..129 2/5 (40%)
NmnatNP_651315.2 NMNAT_Eukarya 46..282 CDD:185681 114/250 (46%)

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