Protein Alignment Dhrs7 and CG31937

DIOPT Version :10

• Sequence 1: NP_079798.2
• Gene: Dhrs7 / 66375
• MGIID: 1913625
• Length: 338
• Species: Mus musculus
• Sequence 2: NP_608616.2
• Gene: CG31937 / 326177
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 110/300 - (36%)
• Similarity: 162/300 - (54%)
• Gaps: 18/300 - (6%)

Mouse     4 ELLLWLLALCALILPLVQLLRFLRADADLTLLWAEWQGRRPEWELTDM---VVWVTGASSGIGEE 65
            |.||.||.|..::..|:.:|    .|.::.|    |...|....|:.|   |||:||||||||..
  Fly     5 EFLLLLLVLYYVVYVLLWIL----LDCNVAL----WYKSRFGVSLSSMRGQVVWITGASSGIGRA 61

Mouse    66 LAFQLSKLGVSLVLSARRAQELERVKRRCL--ENGNLKEKDILVLPLDLTDTSSHEAATKAVLQE 128
            ||..|::.||.|||||||.::||:|:..||  ..|.|..||:||:.:|:.|...|:.....||..
  Fly    62 LALSLARHGVKLVLSARRLEQLEQVQEECLAAARGLLATKDVLVIQMDMLDLDEHKTHLNTVLNH 126

Mouse   129 FGKIDILVNNGGRSQRSLVLETNLDVFKELINLNYIGTVSLTKCVLPHMIERK--QGKIVTVNSI 191
            |.::|:||||.|||||:...|..::|.:||..|:....|.|::.|:.:.:|:.  :|.|...:||
  Fly   127 FHRLDVLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSI 191

Mouse   192 AGIASVSLSSGYCASKHALRGFFNALHSELGQYPGITFCNVYPGPVQSDIVKNAFTEEVTKSMRN 256
            ||.:.|..|..|||:||||..:..:|..|:.:.....|.   |||:.:|.::.|||......:..
  Fly   192 AGFSPVPFSPTYCAAKHALNAYLLSLKVEMRKLDVSLFA---PGPIATDFLQEAFTGSQGGKVGL 253

Mouse   257 NIDQSYKMPTSRCVRLMLISMANDLKEVWISDHPVLLGAY 296
            :.....:|...||..|..:::||.:...|....||.|.||
  Fly   254 STANQKRMTAQRCGDLFAVALANKMDLTWCGLFPVNLLAY 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhrs7	NP_079798.2	11beta-HSD1_like_SDR_c	48..308	CDD:187593	97/255 (38%)
CG31937	NP_608616.2	Rossmann-fold NAD(P)(+)-binding proteins	44..293	CDD:473865	95/251 (38%)