Protein Alignment SLC2A3 and CG14606

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_001334690.1
• Gene: CG14606 / 40866
• FlyBaseID: FBgn0037485
• Length: 466
• Species: Drosophila melanogaster
• Alignment Length: 430
• Identity: 107/430 - (24%)
• Similarity: 188/430 - (43%)
• Gaps: 76/430 - (17%)

Human    68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCG 132
            ::..:|.:.|:...||.::|.||:..|.   .||:....:..|...|:.|..|..||.:.|:..|
  Fly    68 SLIGLGSLTGNIIFGLLLDRLGRKVCMY---FLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGG 129

Human   133 LCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAIL 197
            .|...:|::|.||:..::|||..::..:.:.:|::|.      |.|.|      .|.:.::|.|:
  Fly   130 GCYVVLPIFIAEIADNSVRGALSSMAMMYVSIGMMVG------FTLAS------YLPYYLMPCII 182

Human   198 QSAALPF--------CPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQ 254
              .|||.        ..|:|::||...::::..|........|...|.|.:..:.::|::.
  Fly   183 --VALPVVFMLSVIGLSETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIE---- 241

Human   255 VTVLELFRVS----------SYRQPIIIS--------IVLQLSQQLSGINAVFYYSTGIFKDAGV 301
               .:.||:.          |:|..|.:.        .||.:..||||..|:|.|::.||.:.|.
  Fly   242 ---FDTFRLQVLSGGVTESISWRDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGN 303

Human   302 Q-EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLL---LKD---NY 359
            . :|..:||..|....:....::.||:|.|||.|.:..:|||....  :.::||   ..|   |.
  Fly   304 NLDPNTSTIVVGAAQLVGIFSAVVLVDRLGRRVLLLTSMGGMGLGE--LAIALLKCFASDEFLNQ 366

Human   360 NGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAA 424
            ||...:.|..::..:|  .:|...:.:.|:.||.     ||.:...|.|...:.| .|.:|.:..
  Fly   367 NGWLPLVIMCLVACIA--SLGVIALIFIIIIELL-----PAKIRSIGTSLSMATF-SGFIFVALK 423

Human   425 HY--------LGAYVFIIFTGFLITFLAFTFFKVPETRGR 456
            .|        |.|.:|:.....|..|:....| :|||:|:
  Fly   424 IYPTMIYDQGLAATMFMSAGMCLFGFIVLGLF-LPETKGK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	106/428 (25%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		4/5 (80%)
CG14606	NP_001334690.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143943
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840