Protein Alignment SLC2A3 and CG42825

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_729590.1
• Gene: CG42825 / 39179
• FlyBaseID: FBgn0262007
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 454
• Identity: 95/454 - (20%)
• Similarity: 165/454 - (36%)
• Gaps: 122/454 - (26%)

Human    72 VGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLC---KVAKSVEMLILGRLVIGLFCGL 133
            :|.:||:.......|:..::..:...::|...||..:. |   ..|.:.....|..:..||.
  Fly   119 IGAIIGALVTMALTNKVAKKYILQFSSVLVTVGGLVIA-CTHNNGAGTTAACYLDGIANGLV--- 179

Human   134 CTGFVPM--YIGEISPTALRG-AFGTLNQLGIVVGILVAQIFGLEFILG---------SEELWPL 186
               |.|.  .:||||...||| |..||.||....|||:..::...:...         ||.:..:
  Fly   180 ---FAPFMALVGEISVPYLRGKASATLEQLCFGTGILLQILYVSNWTYSSYMTYNDFTSENMKGV 241

Human   187 LLG-FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR-- 248
            |.. :.:|..|:.|.   |..|||..:|.| .||:.|...|:||.....::::..|:..|..|
  Fly   242 LSTIYGVLALIMGSF---FTIESPVLMLAN-NEEQAAIDALRRLQKPAVLTEETYELLAEHKRYL 302

Human   249 -----MSQEKQVT-------------VLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGI 295
                 ||:.:.::             .|....:||:   :||:.|:.:.......||..:|
  Fly   303 AYNKNMSKSESISKALPTFMRLAYLRALNAMSISSF---VIITYVVAILVSNDLRNASSWY---- 360

Human   296 FKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYN 360
                         ||......:.:::..|.:|..||:...:.||  :..|.    :|..:...||
  Fly   361 -------------IGLAFCRWLGSLIPSFCMESLGRKKPAVFGL--LVSCG----LSFAVGSQYN 406

Human   361 GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNW-TSNFLVGLLFPSAA 424
            ..:::....:|:               ::.|.|      |.||.:..|.: |..:.:|:    ..
  Fly   407 VYTYMSQVTVLI---------------MIFEFF------AGMAFSSNSAYLTEAYPMGV----KQ 446

Human   425 HYLG-AYVFIIFTGFLITFLAFTF----------------------FKVPETRGRTFEDITRAF 465
            |::| .::..||...:|....|.|                      ..:||||..|.:.....|
  Fly   447 HFIGLTFITEIFVFLIINVCDFNFGQGYNYFYIMGAMYLAGVILGVLTLPETRRMTLQGAQEQF 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	93/443 (21%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		0/5 (0%)
CG42825	NP_729590.1	MFS	116..490	CDD:119392	89/432 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840