Protein Alignment SLC2A3 and CG32053

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_729587.1
• Gene: CG32053 / 39178
• FlyBaseID: FBgn0052053
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 413
• Identity: 89/413 - (21%)
• Similarity: 175/413 - (42%)
• Gaps: 57/413 - (13%)

Human    72 VGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTG 136
            :|.:||:...|.|...|..:..|...:|:.:|||..|.:.::  .::.|:.||.:.||..||...
  Fly    98 IGAIIGALLGGFFSRWFPYKTLMEFCSLITITGGIVMAVNRM--DLDALLAGRYMNGLANGLAIA 160

Human   137 FVPMYIGEISPTALRGAFGTLNQ-----LGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAI 196
            ......||:|....||...:..:     :||.|.|:.:..:.::.....|:...:|.|  :|.:|
  Fly   161 PTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSG--VLGSI 223

Human   197 LQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDV-SQDIQEMKDESARMSQEKQV----T 256
            ....|.....|||..|| .:..|:.|.|.|.||...:.| ::...:::|....:...:.:    .
  Fly   224 ALLLAFLLSIESPVDLL-EQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRSMGWRHA 287

Human   257 VLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVV 321
            :..|.|:|..|....:|:.:.::..|:      :.||.::.|:.....::     |.:..:.:..
  Fly   288 LPALVRLSVLRALYALSLSVMVAFTLA------WTSTEVYGDSSGPYVLF-----GFLRLMGSFT 341

Human   322 SLFLVERAGRRTLHMIGL--GGMAFCSTLMTVSLLLKDNYNG---MSF----VCIGAILVFVAFF 377
            :.|.::..||:...::||  .|...|.        |...:.|   ::|    :.:..:|::..|.
  Fly   342 TSFALDSLGRKIPLLLGLVISGCLACG--------LASRFAGSHPLTFSGNRMALWLLLIYQLFA 398

Human   378 EIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLL--------FPSAAHYLGAYVFII 434
            .|...|...:: :|.|.:..:...:|:    .:....:|.||        ..|.:.|:..|.||:
  Fly   399 GIAFAPSSSYL-SEAFPRRIKRPCIAI----TYILEIIVQLLLRQMDFAAIGSDSSYVALYFFIL 458

Human   435 FTGFLITFLAFTFFKVPETRGRT 457
             .|.|:....|:.:.:|||:..|
  Fly   459 -GGLLLAGFLFSVWYMPETKDTT 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	88/410 (21%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		1/5 (20%)
CG32053	NP_729587.1	MFS	73..428	CDD:119392	74/358 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143955
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840