Protein Alignment SLC2A3 and CG7882

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_610189.2
• Gene: CG7882 / 35520
• FlyBaseID: FBgn0033047
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 169/469 - (36%)
• Similarity: 259/469 - (55%)
• Gaps: 19/469 - (4%)

Human     2 GTQKVTPALIFAITVATIGS-----FQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTS 61
            |.|:..|...:::..|.|||     ...||.|||:|:|.::::.:.|:||....:...|:..|..
  Fly    28 GKQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNETLIASYDLNLSDAGLEI 92

Human    62 LWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLV 126
            |||..|:||.|||.|||.......||||||....|..||...|......|:..:|||:|:|||::
  Fly    93 LWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGLLLGLGAISFYACRPLRSVELLLLGRMM 157

Human   127 IGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFT 191
            :||..||.|.|:.|:..|||..:.|.....|..:|:.:|:::||:..|..:||..|.|...|.|.
  Fly   158 VGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIAQVCSLRSVLGGPENWHFGLAFY 222

Human   192 ILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRL----WGTQDVSQDIQEMKDESARMSQE 252
            .|..::..|...:.||||::|.|.:..:|:|::.||.|    .|:..:..:::||:.|||  .:.
  Fly   223 GLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGYTAGSAALKAEMEEMEQESA--CEV 285

Human   253 KQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QEPIYATIGAGVVN 315
            |..:::::.|....|.|:||.......||||||||:||||..||:.||:  |...:|.:|||.:|
  Fly   286 KTSSLMQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSLN 350

Human   316 TIFTVVSLFLVERAGRRTLHMIGLGGMAFCST---LMTVSLLLKDNYNGMSFVCIGAILVFVAFF 377
            ...:::...|:||..||.|.:.   ...||:.   |..:.|...::|:.....|||.|.:::.||
  Fly   351 LFASMLGPVLLERVNRRPLMLF---STFFCAVFLLLFAIMLFFIESYSWFGMGCIGCIFLYIFFF 412

Human   378 EIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITF 442
            :.|.||:|:||.||||....|||||::...:.|..||::|:.||:..:..||.||:.|:...:..
  Fly   413 QFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFPTMQNLWGALVFLPFSVTCLLI 477

Human   443 LAFTFFKVPETRGR 456
            ...|...:||||||
  Fly   478 FGLTKRYLPETRGR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	164/457 (36%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		5/5 (100%)
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	164/452 (36%)
		MFS	95..480	CDD:119392	141/389 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143973
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	0.197	Inparanoid score	I2535
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.800