Protein Alignment PINK1 and Pink1

DIOPT Version :8

• Sequence 1: NP_115785.1
• Gene: PINK1 / 65018
• HGNCID: 14581
• Length: 581
• Species: Homo sapiens
• Sequence 2: NP_001100164.1
• Gene: Pink1 / 298575
• RGDID: 1305769
• Length: 257
• Species: Rattus norvegicus
• Alignment Length: 241
• Identity: 189/242 (78%)
• Similarity: 204/242 (84%)
• Gaps: 1/242 (0%)

Human     1 MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVGLGLPN 65
            |||||||||||||||||||||..|||...|.|:|||.|...||||||..:.|||:||.:||.||:
  Rat     1 MAVRQALGRGLQLGRALLLRFAPKPGPVSGWGKPGPGAAWGRGERPGRVSSPGAQPRPLGLPLPD 65

Human    66 RLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRRAVSACQEIQA 130
            |.|||||||||||||:||||||||.|.|||||||||||||||||||||||||||||.||||||||
  Rat    66 RYRFFRQSVAGLAARIQRQFVVRARGGAGPCGRAVFLAFGLGLGLIEEKQAESRRAASACQEIQA 130

Human   131 IFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQNLEVTKSTGLLPGRG 195
            |||||:|...|||||||.||||||:|||||:|||||:|||||||||||||:||..|..||| |:|
  Rat   131 IFTQKNKQVSDPLDTRRWQGFRLEDYLIGQAIGKGCNAAVYEATMPTLPQHLEKAKHLGLL-GKG 194

Human   196 PGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQEL 241
            |...:.|...|:||||||||.||||||||||||||||||:.|||||
  Rat   195 PDVVSKGADGEQAPGAPAFPFAIKMMWNISAGSSSEAILSKMSQEL 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PINK1	NP_115785.1	STKc_PINK1	162..512	CDD:270920	60/81 (74%)
Pink1	NP_001100164.1	PKc_like	162..>240	CDD:304357	59/79 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG4158
HGNC	1	1.500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H32672
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D124353at32523
OrthoFinder	1	1.000				FOG0007807
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR22972
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.520