DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATL2 and Atl2

DIOPT Version :9

Sequence 1:	NP_001317392.1	Gene:	ATL2 / 64225	HGNCID:	24047	Length:	584	Species:	Homo sapiens
Sequence 2:	NP_001094141.1	Gene:	Atl2 / 298757	RGDID:	1305125	Length:	583	Species:	Rattus norvegicus

Alignment Length:	582	Identity:	531/582 - (91%)
Similarity:	549/582 - (94%)	Gaps:	1/582 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCPVQIVL 65
            |||||||||.|||.|||.|||:|||.|..||||||||||||:|||.|||||||||:|||||||||
  Rat     1 MAEGDEAARRQQPQQGLRRRRQTSDSSVGVNHVSSTTSLGEDYEDADLVNSDEVMRKPCPVQIVL 65

Human    66 AHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGN 130
            ||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||:
  Rat    66 AHEDDHNFELDEEALERILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGS 130

Human   131 NEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALST 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 NEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALST 195

Human   196 MTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 MTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260

Human   261 QFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELR 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 QFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELR 325

Human   326 NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGA 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGA 390

Human   391 RDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEET 455
            ||.||:|||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat   391 RDAYCRSMEQVCGGDKPYIAPSDLERKHLDLKEVALKQFRSVKKMGGDEFCRRYQDQLEAEIEET 455

Human   456 YANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAY 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||..||||||
  Rat   456 YANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALTSLCTWAY 520

Human   521 VKYSGEFREIGTVIDQIAETLWEQRSPRKVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKK 582
            ||||||||||||:|||:||||||| ..:.:...|.|...|:.|..::.:....::|.:...|
  Rat   521 VKYSGEFREIGTMIDQVAETLWEQ-VLKPLGDNLMEENIRQSVTNSIKAGLTDQVSHHARLK 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATL2	NP_001317392.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44		34/42 (81%)
ATL2	NP_001317392.1	GBP	70..341	CDD:280433	268/270 (99%)
Atl2	NP_001094141.1	GBP	70..341	CDD:280433	268/270 (99%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83684161
Domainoid	1	1.000	554	1.000	Domainoid score	I5772
eggNOG	1	0.900	-	-		E1_KOG2037
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56949
Inparanoid	1	1.050	1141	1.000	Inparanoid score	I4438
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG58971
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	1	1.000	-	-		FOG0001595
OrthoInspector	1	1.000	-	-		oto136199
orthoMCL	1	0.900	-	-		OOG6_102856
Panther	1	1.100	-	-	LDO	PTHR10751
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1147
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270