Protein Alignment ATL2 and Atl2

DIOPT Version :10

• Sequence 1: NP_001317392.1
• Gene: ATL2 / 64225
• HGNCID: 24047
• Length: 584
• Species: Homo sapiens
• Sequence 2: XP_063117669.1
• Gene: Atl2 / 298757
• RGDID: 1305125
• Length: 584
• Species: Rattus norvegicus
• Alignment Length: 584
• Identity: 564/584 - (96%)
• Similarity: 573/584 - (98%)
• Gaps: 0/584 - (0%)

Human     1 MAEGDEAARGQQPHQGLWRRRRTSDPSAAVNHVSSTTSLGENYEDDDLVNSDEVMKKPCPVQIVL 65
            |||||||||.|||.|||.|||:|||.|..||||||||||||:|||.|||||||||:|||||||||
  Rat     1 MAEGDEAARRQQPQQGLRRRRQTSDSSVGVNHVSSTTSLGEDYEDADLVNSDEVMRKPCPVQIVL 65

Human    66 AHEDDHNFELDEEALEQILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGN 130
            ||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||:
  Rat    66 AHEDDHNFELDEEALERILLQEHIRDLNIVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGS 130

Human   131 NEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALST 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 NEPLTGFTWRGGCERETTGIQVWNEVFVIDRPNGTKVAVLLMDTQGAFDSQSTIKDCATVFALST 195

Human   196 MTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 MTSSVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEGGK 260

Human   261 QFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELR 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 QFLEKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKDIDEDFKRELR 325

Human   326 NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGA 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 NLVPLLLAPENLVEKEISGSKVTCRDLVEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVAGA 390

Human   391 RDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQFRSVKKMGGDEFCRRYQDQLEAEIEET 455
            ||.||:|||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
  Rat   391 RDAYCRSMEQVCGGDKPYIAPSDLERKHLDLKEVALKQFRSVKKMGGDEFCRRYQDQLEAEIEET 455

Human   456 YANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALIFLCTWAY 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||..||||||
  Rat   456 YANFIKHNDGKNIFYAARTPATLFAVMFAMYIISGLTGFIGLNSIAVLCNLVMGLALTSLCTWAY 520

Human   521 VKYSGEFREIGTVIDQIAETLWEQRSPRKVFSKLFEVTRRRMVHRALSSAQRQRLSSNNNKKKN 584
            ||||||||||||:|||:|||||||||||||||||||||||||||.|||||||||||||||||||
  Rat   521 VKYSGEFREIGTMIDQVAETLWEQRSPRKVFSKLFEVTRRRMVHHALSSAQRQRLSSNNNKKKN 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATL2	NP_001317392.1	N-terminal hypervariable region (HVR). /evidence=ECO:0000250|UniProtKB:Q8WXF7	1..60		48/58 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		34/42 (81%)
		GBP	70..341	CDD:460516	268/270 (99%)
		3HB (three-helix bundle) domain. /evidence=ECO:0000250|UniProtKB:Q8WXF7	374..465		87/90 (97%)
		Linker. /evidence=ECO:0000250|UniProtKB:Q8WXF7	466..474		7/7 (100%)
Atl2	XP_063117669.1	None